Digital CBT reduced distress in patients with long-term physical health conditions
PharmaTimes
FEBRUARY 19, 2024
Participants who received COMPASS showed a clinically significant improvement after 12 weeks
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With Vtama's success in relieving itching, Dermavant eyes FDA filing in atopic dermatitis
Fierce Pharma
OCTOBER 11, 2023
In the race to develop nonsteroidal topical treatments for autoimmune skin conditions, Dermavant is charging toward the finish line—again. Dermavant has presented evidence that Vtama provides immediate and long-term relief from the severe itch condition pruritus, the most prevalent symptom of atopic dermatitis.
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Are Adults With Diabetes Who Switch to High-Deductible Health Plans at Greater Risk for Complications?
Pharmaceutical Commerce
MARCH 26, 2024
A study of patients with the long-term conditions who are required to switch to high-deductible health plans could potentially be more likely to experience diabetes complications than those who stay in standard insurance plans.
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Capsule formulation: future trends
European Pharmaceutical Review
JULY 10, 2023
Gelatine also poses potential long-term performance challenges” Several major trends have emerged in recent years in the capsule space. For example, there have been capsules created that allow for monitoring of external conditions, such as pH, and that enable external control over drug release.
Lonza to acquire major biologics manufacturing facility
European Pharmaceutical Review
MARCH 20, 2024
Lonza stated that with committed volumes over the medium term, this will be phased out as the facility shifts to accommodate alternative customers. Additionally, under the terms of the deal, approximately 750 Genentech employees at the Vacaville (US) facility will be offered employment by Lonza.
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Could small molecule medicine treat rare liver disease?
European Pharmaceutical Review
JULY 3, 2023
“[The small molecule treatment] could provide an important new therapeutic option for long-term treatment of patients with this debilitating condition” “These are encouraging results that suggest elafibranor could be an effective treatment to prevent progression of PBC in patients who have received UDCA. There are 22.27
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Long-term data indicates “significant” potential of aGvHD microbiome treatment
European Pharmaceutical Review
APRIL 15, 2024
Based on the long-term survival data, at 18 months MaaT013 enabled 42 percent overall survival in all patients and 58 percent in responder patients. MaaT013 shows remarkable efficacy at 18 months, yielding more complete responses in aGvHD patients who have shown resistance to current treatments, as compared to other available therapies.
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Expanding ketamine’s horizons to treat rare neurological disorders
Pharmaceutical Technology
NOVEMBER 29, 2022
Earlier this month, New Jersey-based Silo Pharma announced the start of an IND-enabling study of a topical ketamine formulation for fibromyalgia, a chronic condition that causes pain and fatigue. Depression research spurs efforts for other conditions. Other companies continue exploring ketamine’s potential in different conditions.
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How predictive analytics in healthcare can improve quality of care and lower care costs
Clarify Health
MARCH 12, 2024
From helping to manage chronic conditions more effectively to improving care coordination to setting the foundation for personalized wellness programs, predictive analytics in healthcare can serve as a secret weapon to boost the quality of the services health plans offer while keeping costs under control.
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10 Trends for online health seekers
World of DTC Marketing
OCTOBER 21, 2020
Here is what I learned: 1ne: Since more people are working at home, they have more time to research health conditions and possible treatments. 9ine: Searches for specific medical terms have increased, indicating that people don’t necessarily understand common medical terms. 2020 trend concept.
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UK digital health project aims to tackle dysfunctional breathing
pharmaphorum
DECEMBER 19, 2022
It would provide an alternative to standard breathing exercises for patients with conditions that affect breathing, including long-term respiratory diseases like asthma, chronic obstructive pulmonary disorder (COPD) and cystic fibrosis, which can be resource-intensive as they require patients to be overseen by a healthcare worker.
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Data Support Biktarvy Tablets for Virologic Suppression Among Patients With HIV
Pharmacy Times
OCTOBER 20, 2023
Biktarvy was found both effective and safe for long-term use in HIV, as well as for patients with mental health conditions.
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FDA-Approved At-Home Spirometer: Interview with Charvi Shetty, Co-Founder and CEO at Aluna
Medgadget
OCTOBER 17, 2022
The device is easy to use, requiring the patient to blow into it daily, and the company envisages the technology as similar to the blood-glucose tests used by patients with diabetes to keep track of their condition. Unfortunately, COVID can cause symptoms for patients with chronic lung conditions to worsen severely.
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Injectable peptide rapidly reduces intracranial pressure
European Pharmaceutical Review
MARCH 13, 2023
IIH is a condition that raises pressure in the brain, likely due to a cerebrospinal fluid (CSF) imbalance. Symptoms include chronic headaches and the condition can also lead to pressure on the optic nerve, which can result in blindness. Weight gain is a major risk factor of developing IIH. This was compared to only 1.5
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Wearable EEG Patch Measures Brain Activity
Medgadget
OCTOBER 25, 2022
Researchers at Osaka University in Japan engineered a wearable electroencephalography (EEG) device that can measure brain activity, potentially letting clinicians monitor conditions such as depression or dementia. This latest technology aims to allow for at-home measurements of brain activity.
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Can we be serious about telehealth?
World of DTC Marketing
AUGUST 14, 2022
Experts say at least 25% of all outpatient, preventive, long-term care and well-being services could be provided via telehealth by 2040.” To understand telehealth, we first must understand what patients are using it for and under what conditions HCPs feel comfortable using it as opposed to an office visit.
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Sanofi to sell Japanese manufacturing plant
European Pharmaceutical Review
OCTOBER 17, 2022
The French pharmaceutical company will also enter into a long-term supply agreement with the CDMO. Conditions include type 1 diabetes, cancer, rheumatoid arthritis and Gaucher disease. The goal is for the CDMO to become a strategic partner to introduce new European, North American and Japanese customers to the manufacturing plant.
European Commission authorises one of first ustekinumab biosimilars in Europe
European Pharmaceutical Review
APRIL 26, 2024
Under terms of the deal, Sandoz was given commercialisation rights for Pyzchiva in the US, Canada, the European Economic Area (EEA), Switzerland, and the UK. Samsung Bioepis is responsible for development, registration, intellectual property (IP), manufacturing and supply.
Cell therapy first for chronic heart failure
European Pharmaceutical Review
FEBRUARY 28, 2023
In the simplest terms, the stem cells are injected directly into the heart muscle and shut down inflammation and begin to heal the cells,” he summarised. Based on the findings, Dr Perin explained to EPR that the trial is significant because the condition “currently is not addressed with medications, which treat the symptoms.”
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Moderna joins the Association of the British Pharmaceutical Industry
European Pharmaceutical Review
JANUARY 15, 2023
As the newest member of the ABPI, the membership will help Moderna to build on its wider long-term commitment to expand its footprint and investment in the UK. Moderna is best known for its work during the COVID-19 pandemic and are now developing a range of mRNA-based vaccines for a number of conditions.
JAK inhibitors increase risk of cardiovascular problems and cancer, warns PRAC
European Pharmaceutical Review
NOVEMBER 1, 2022
The committee advises that Cibinqo (abrocitinib), Jyseleca (filgotinib), Olumiant (baricitinib), Rinvoq (upadacitinib) and Xeljanz (tofacitinib), used for chronic inflammatory conditions, should have limited distribution to minimise risk of serious side effects such as cardiovascular diseases, blood clots, cancer and serious infections.
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Omnichannel is irrelevant with the wrong message
World of DTC Marketing
JANUARY 21, 2022
It is evident that HCPs are extremely time constraint and prefer to engage with pharma organizations on their terms regarding channel, content, and type of devices. I maintain a network of thought leaders in several health conditions, and they all have one thing in common: pharma reps and messages are becoming more irrelevant.
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Beyond the pill in an outcomes-based world
pharmaphorum
JULY 12, 2022
With growing numbers of people around the world living with long-term conditions, the pharmaceutical industry has a golden opportunity to use its expertise to truly enhance lives. By helping people to cope with their long-term condition, mental health support can improve engagement with treatment and self-management.
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Implanted Magnets for Prosthetic Control
Medgadget
NOVEMBER 11, 2022
Importantly, they can assist in very accurately measuring muscle length as the turkeys traversed an obstacle course (yes, really), reflecting real-world conditions outside the lab. However, this approach does not account for muscle activity, in terms of velocity of movement and muscle length during contraction.
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Intratumoral Bacteria as an Injectable Anti-Cancer Treatment
Medgadget
MAY 19, 2023
This often leaves their associated blood vessels in an unreliable and leaky state, and the center of solid tumors often demonstrates poor blood supply and low-oxygen conditions. Recently, researchers have focused on the role of bacteria in fighting cancer. These researchers have now identified a consortium of bacteria that can achieve this.
Engineering 87
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SEO vs. SEM for Healthcare: The Difference Explained
Healthcare Success
MARCH 6, 2024
Achieve long- and short-term goals. We’ll explain how SEM amplifies your web presence quickly and discuss how SEO supports long-term online visibility. Complex medical terms Healthcare organizations must balance complex medical terms and concepts with accurate, accessible, and easy-to-understand content for consumers.
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Content Marketing as a Sales Driver: Unlocking Your Business Potential in the Pharmaceutical Industry
Pharma Marketing Network
JULY 19, 2023
Content Marketing as a Sales Driver: Unlocking Your Business Potential in the Pharmaceutical Industry Content marketing is a long-term strategy that can help businesses of all sizes generate leads, increase brand awareness, and drive sales. Be consistent: Content marketing is a long-term strategy.
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Rare Disease Day 2024: Advocating for Awareness and Support
PM360
FEBRUARY 12, 2024
About 4% of the population are affected, with an estimated thirty million currently living with these conditions. The industry term “orphan diseases” is derived from these neglected conditions whose treatments are often not considered profitable enough due to the limited patient population.
Navigating the World of Medical Device Equipment Sales: Tips for Success
Rep-Lite
APRIL 4, 2024
Clinical Knowledge: Possessing a basic understanding of relevant medical conditions and procedures related to your devices will enhance your interactions with healthcare providers. Building Trusting Relationships Focus on Long-Term Partnerships: Selling medical devices is not about quick transactions.
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Our healthcare has failed us
World of DTC Marketing
SEPTEMBER 17, 2020
Concerns about the impact of obesity have taken on new dimensions this year as having obesity is one of the underlying health conditions associated with the most serious consequences of COVID infection, including hospitalization and death. So what’s being done?
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GSK to exclusively license novel oral antifungal
European Pharmaceutical Review
MARCH 30, 2023
AMR surveillance must improve, says WHO report… Terms of the exclusive licence agreement Under the agreement, GSK will make an upfront payment to SCYNEXIS of $90 million, plus additional potential milestone-based payments totalling $503 million.
Belt Monitors Heart Failure Patients
Medgadget
DECEMBER 21, 2022
The condition can be debilitating and life altering, and is progressive. Many heart failure patients must undergo repeat hospital admission as their condition deteriorates. Finding a way to monitor such patients while they are at home could yield dividends in terms of early intervention and better patient outcomes.
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The Benefits of a Sales Pilot for Pharmaceutical Products
MaBiCo
FEBRUARY 20, 2023
The Benefits of a Sales Pilot for Pharmaceutical Products A sales pilot is a short-term experiment that tests a product’s sales performance or a new sales approach. Moreover, thanks to sales pilots, companies can adapt quickly to changing market conditions, can spot new opportunities and stay ahead of competition.
Roche to gain rights to novel antibody for IBD
European Pharmaceutical Review
OCTOBER 23, 2023
Roche will also pay a near-term milestone payment of $150 million. The recent Phase IIb for RVT-3101 delivered the first long-term, robust dataset demonstrating improved clinical remission in the maintenance treatment phase,” stated Dr Levi Garraway, Roche’s Chief Medical Officer and Head of Global Product Development.
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Vertex signs licence deal with CRISPR Therapeutics for diabetes therapies
Pharmaceutical Technology
MARCH 28, 2023
Under the terms of the deal, the company will receive non-exclusive rights to CRISPR/Cas9, a gene-editing technology of CRISPR Therapeutics, for the development of potentially curative T1D cell therapies. The gene-editing technology allows for precise, directed changes to genomic DNA. The system comprises the Cas9 enzyme and a guide RNA.
Astellas Pharma agrees to buy Iveric bio for about $5.9bn
Pharmaceutical Technology
MAY 1, 2023
Under the deal terms, the company, through Astellas US Holding’s wholly owned subsidiary Berry Merger Sub, will acquire all the outstanding Iveric Bio shares for $40.00 Astellas Pharma has entered into a definitive agreement to buy US-based biopharmaceutical company Iveric bio, in a deal valued at nearly $5.9bn. in cash for each share.
Dupixent nears EU approval for rare skin disease prurigo nodularis
pharmaphorum
NOVEMBER 14, 2022
At the moment, treatment typically involves oral or topical corticosteroids, antihistamines, and some antidepressant drugs, but responses are often inadequate, vary widely between patients, and come with the burden of safety risks if used long-term. Sales of Dupixent rocketed 45% to around $2.4
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EMA accepts Sandoz’s marketing applications for biosimilar denosumab
Pharmaceutical Technology
MAY 26, 2023
The MAAs include all indications covered by the Xgeva (denosumab) and Prolia (denosumab) reference medicines to treat conditions such as osteoporosis in postmenopausal women. Other conditions include the prevention of skeletal-related complications in cancer that has spread to the bones, as well as treatment-induced bone loss.
Three different ways AI will shape the future of the pharma industry
Impetus Digital
MARCH 15, 2024
Risk prediction can also be particularly important when understanding how different drugs might interact with each other – a vital component for many people with long-term health conditions. We’re all prone to coughs and colds, sickness bugs, and even more serious health concerns such as cancer.
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Refillable Device for Drug Delivery Past the Blood-Brain Barrier: Interview with Mike Maglin, CEO at CraniUS
Medgadget
SEPTEMBER 29, 2023
The implant can be easily refilled from outside, allowing for long-term, minimally invasive drug treatment. Conn Hastings, Medgadget: Please give us an overview of the blood-brain barrier, and how it affects treatment for a variety of brain-based conditions. It is also wireless and can even be charged wirelessly.
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Lilly will acquire Akouos to accelerate hearing loss therapies
European Pharmaceutical Review
OCTOBER 19, 2022
Eli Lilly is set to acquire Akouos, Inc, a precision genetic medicine company developing first-in-class adeno-associated viral gene therapies for treating inner ear conditions like sensorineural hearing loss. . Under the terms of the deal, Lilly will acquire all outstanding shares of Akouos for $12.50
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New Study Demonstrates Consistent Positive Long-Term Adherence and Efficacy of Nerivio® for Treatment of Migraine
Legacy MEDSearch
OCTOBER 25, 2023
Theranica , a neuromodulation therapeutics company, announced the publication of a comprehensive clinical study in Advances in Therapy examining the long-term utilization, clinical efficacy, and safety of Nerivio ® , a Remote Electrical Neuromodulation (REN) device for the treatment of migraine. Are you hiring?
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Smartphone Photos to Detect Anemia
Medgadget
MARCH 9, 2023
The technology could be particularly useful in identifying anemia in children in remote areas, as the condition can significantly affect their development. An affordable and reliable technique to screen for anemia using a smartphone could drive long-term improvements in quality of life for a large amount of people.”
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Gilead’s $658.5m immunotherapy collaboration
European Pharmaceutical Review
JANUARY 4, 2023
We are excited to collaborate with EVOQ [in our aim to address] the needs of people living with these conditions.”. Under the terms of the agreement, the sum EVOQ could potentially gain will come from upfront, option exercise and milestone payments across all programmes, as well as tiered royalties on product sales.
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