2025

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Novavax Sees Sanofi Vaccine Pact as Model for Future Deals, Some Going Beyond Infectious Disease

MedCity News

Novavax’s partnership with Sanofi allows the pharma giant to explore potential combinations of assets from both companies, and it’s a blueprint for the kinds of alliances the vaccine developer is pursuing. Rather than commercializing vaccines, Novavax aims to turn its research into business development deals, R&D executive Ruxandra Draghia-Akli said.

Pharma 336
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A New Era in Pharma DTC Marketing: Trust Over TV Spots

World of DTC Marketing

For decades, the image of pharmaceutical direct-to-consumer (DTC) marketing has been defined by glossy TV commercials: smiling patients, soft music, lengthy lists of side effects spoken at a rapid pace, and vague promises of a better life. But that era is quickly becoming obsolete. We’re entering a new era of pharma DTC marketing—one grounded not in big ad budgets and prime-time placement, but in trust, transparency, and easy-to-understand health information.

Marketing 252
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Fierce Pharma - Untitled Article

Fierce Pharma

Chinese regulators have approved four new drugs developed by local biopharma companies, including a first-of-its-kind molecule in blood cancer.

Biopharma 253
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Pricing watchdog will take on the rising cost of drugs at launch

PharmaVoice

ICER’s upcoming report could shed light on how the launch price of newly approved drugs affects overall cost and access from a patient perspective.

Patients 226
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State of AI in Sales & Marketing 2025

AI adoption is reshaping sales and marketing. But is it delivering real results? We surveyed 1,000+ GTM professionals to find out. The data is clear: AI users report 47% higher productivity and an average of 12 hours saved per week. But leaders say mainstream AI tools still fall short on accuracy and business impact. Download the full report today to see how AI is being used — and where go-to-market professionals think there are gaps and opportunities.

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Why CVS, Express Scripts Are Suing Over the Arkansas PBM Law

MedCity News

Arkansas became the first state to pass a law banning pharmacy benefit managers from owning pharmacies, aiming to curb their market power and reduce drug costs. But major PBMs like CVS and Express Scripts are suing, claiming the law is unconstitutional. The post Why CVS, Express Scripts Are Suing Over the Arkansas PBM Law appeared first on MedCity News.

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Vertex Pharma’s Type 1 Diabetes Cell Therapy Shows Potential to Achieve Insulin Independence

MedCity News

In Phase 1/2 results for 12 patients at least one year after receiving the cell therapy, zimislecel, Vertex Pharmaceuticals reported all participants achieved blood glucose in the target range and 10 of the 12 were free of exogenous insulin as of the data cutoff. Vertex expects to complete enrollment in the pivotal portion of the study this summer, paving the way for potential regulatory submissions next year.

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Safety Risk Sinks Cargo Therapeutics’ Cancer Cell Therapy Prospect, Leading to 50% Staff Cut

MedCity News

Phase 2 data for Cargo Therapeutics CD22-targeting cell therapy show low durability and cases of a severe immune response, some that were classified as grade 4 or 5 serious adverse events. Cargo is discontinuing the study and shifting focus to a different cell therapy on track to begin Phase 1 testing in mid-2025. The post Safety Risk Sinks Cargo Therapeutics Cancer Cell Therapy Prospect, Leading to 50% Staff Cut appeared first on MedCity News.

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Healthcare Leaders Support FTC’s Second Report on PBMs, While PBMs Criticize Findings

MedCity News

On Tuesday, the Federal Trade Commission released its second interim staff report on prescription drug middlemen. The report examines the impact of PBMs (specifically CVS Caremark, Express Scripts and Optum Rx) on specialty generic drugs, highlighting substantial price markups by PBMs on medications for cancer, HIV and other conditions. The post Healthcare Leaders Support FTC’s Second Report on PBMs, While PBMs Criticize Findings appeared first on MedCity News.

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Open Source Healthcare – The Cure for Stagnant Medical Innovation

MedCity News

We are living in a moment when many realize that collaboration yields better, faster and more affordable advances. Open source also enables the potential for bigger profits and revenue. Whats in reach: a small amount of money paid for treatments across millions of people, rather than expensive lifesaving treatments only for the few who can afford them.

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The Future of Training: How Virtual Reality Can Protect Clinicians from Healthcare-associated Infections

MedCity News

VR allows learners to actually see the virtual germs responsible for causing infections and spreading disease, which could otherwise only be seen under a microscope. The technology also heightens users’ senses, drawing their attention to things they would be unable to see in traditional learning environments. The post The Future of Training: How Virtual Reality Can Protect Clinicians from Healthcare-associated Infections appeared first on MedCity News.

Training 305
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The Intersection of AI and Sales: Personalization Without Compromise

Speaker: Jesse Hunter and Brynn Chadwick

Today’s buyers expect more than generic outreach–they want relevant, personalized interactions that address their specific needs. For sales teams managing hundreds or thousands of prospects, however, delivering this level of personalization without automation is nearly impossible. The key is integrating AI in a way that enhances customer engagement rather than making it feel robotic.

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Novo Nordisk Adds Obesity and Diabetes to AI Drug Research Pact With Flagship’s Valo Health

MedCity News

Novo Nordisk and Valo Health have collaborated on the development of cardiovascular disease drugs since 2023. Expanding the alliance to cardiometabolic diseases nearly doubles the number of programs covered under the agreement. The post Novo Nordisk Adds Obesity and Diabetes to AI Drug Research Pact With Flagships Valo Health appeared first on MedCity News.

Biopharma 317
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AI Developers Need Real-World Data — and Atropos Health Is Stepping Up to Help

MedCity News

Many healthcare AI developers lack access to real-world data. To address this, Atropos Health is allowing AI developers to train and deploy their models using its real-world evidence network. The federated healthcare data network consists of more than 300 million patient records gathered from EHRs, claims data and patient registries. The post AI Developers Need Real-World Data and Atropos Health Is Stepping Up to Help appeared first on MedCity News.

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Galapagos Keeps Focus on Cancer Cell Therapy, Spins Out Rest of Biz Into NewCo Backed by €2.4B

MedCity News

Galapagos said the planned business separation will leave the legacy company free to focus on developing cell therapies for cancer. An accompanying corporate restructuring will shave Galapagoss headcount by 40%. The post Galapagos Keeps Focus on Cancer Cell Therapy, Spins Out Rest of Biz Into NewCo Backed by 2.4B appeared first on MedCity News.

Biopharma 296
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How Smarter Metrics Can Unlock AI’s Potential in Healthcare

MedCity News

Healthcare doesn’t reward shortcuts. It rewards outcomes. AI will play a critical role in shaping those outcomes — but only if leaders measure what truly matters. The best AI implementations elevate expertise, improve quality and create space for innovation. The post How Smarter Metrics Can Unlock AI’s Potential in Healthcare appeared first on MedCity News.

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AI Strategies for Sales Managers: How to Cut Down on Tedious Admin Work

What if you could help your sellers stop wasting 72% of their day on non-selling activities and focus on bringing in revenue? Incorporating AI in your enablement workflows can help you cut down on busy work, get projects done faster, and let your team (and you!) focus on making a bigger impact. We put together this guide to show you how to use AI to cut time and costs for projects, including collateral creation, development of training videos, and automating tedious processes.

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Merck Is Embracing AI, But ‘We Always Have a Human in the Loop,’ Exec Says

MedCity News

Mercks implementation of artificial intelligence in drug research includes analyzing years of existing Merck clinical data to help identify which drugs and drug combinations to pursue. But Merck executive Matt Studney said AI is tool to help, not replace humans. The post Merck Is Embracing AI, But We Always Have a Human in the Loop, Exec Says appeared first on MedCity News.

Biopharma 273
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Broadening Biomarker Validation for Alzheimer’s Disease Diagnosis Globally

MedCity News

Demonstrating the clinical utility and cost-effectiveness of innovative blood-based biomarker tests can help pave the way for making timely AD diagnosis and proactive care the norm. The post Broadening Biomarker Validation for Alzheimer’s Disease Diagnosis Globally appeared first on MedCity News.

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AI in Clinical Settings: Balancing Innovation, Patient Care, and Personalized Medicine

MedCity News

AI addresses the disconnect between recommended guidelines and action by increasing engagement with personalized, actionable education and updates at appropriate times, The post AI in Clinical Settings: Balancing Innovation, Patient Care, and Personalized Medicine appeared first on MedCity News.

Medicine 308
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How Health Insurers Are Embracing Technology to Serve Real People

MedCity News

The time to innovate is now. By embracing transformative solutions, insurers and employers can not only address systemic challenges but also create a future where healthcare is equitable and sustainable. The post How Health Insurers Are Embracing Technology to Serve Real People appeared first on MedCity News.

Insurance 297
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Medtech Startup Quibim Corrals $50M to Advance AI Analysis in Medical Imaging

MedCity News

Quibims technology applies artificial intelligence analysis to medical images to detect biomarkers. Hospitals and biopharma companies are among the startups customers, using its technology to analyze images to detect disease and guide clinical trial enrollment. The post Medtech Startup Quibim Corrals $50M to Advance AI Analysis in Medical Imaging appeared first on MedCity News.

Medical 298
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Americans’ Trust in the Healthcare System Is Plummeting. How Can It Be Repaired?

MedCity News

Trust in the U.S. healthcare system is eroding, but experts say rebuilding it is possible. They say this will require both payers and providers to prioritize empathy, transparency and personalized communication. The post Americans Trust in the Healthcare System Is Plummeting. How Can It Be Repaired? appeared first on MedCity News.

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Metsera’s IPO Raises $275M to Show How Its Obesity Drugs Can Top Current GLP-1s

MedCity News

Investors showed appetite for Metseras IPO, as shares of the clinical-stage metabolic medicines biotech popped 47% in their Nasdaq debut. Maze Therapeutics and Beta Bionics also priced IPOs; the three companies raised $636 million combined. The post Metseras IPO Raises $275M to Show How Its Obesity Drugs Can Top Current GLP-1s appeared first on MedCity News.

Medicine 297
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How Technology and Value-Based Models Will Reshape Healthcare by 2035

MedCity News

The decade ahead will test our healthcare system like never before. But within these challenges lies an opportunity to create a more accessible, effective, and sustainable healthcare system if we dare to innovate and adapt to the changing landscape. The post How Technology and Value-Based Models Will Reshape Healthcare by 2035 appeared first on MedCity News.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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How the Health Sector Can Change Vaccine Messaging Amid Rising Anti-Vaccine Sentiment

MedCity News

Robert F. Kennedy Jr.s rise to become secretary of the Department of Health and Human Services has some concerned that anti-vaccine policies are coming. If the nations top public health agency pulls support of vaccination, other healthcare stakeholders will need to step up to fill the vaccine messaging void. The post How the Health Sector Can Change Vaccine Messaging Amid Rising Anti-Vaccine Sentiment appeared first on MedCity News.

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Inside Healthcare’s Hottest New AI Category: Agentic AI

MedCity News

Healthcare organizations are starting to implement AI agents autonomous, task-specific systems designed to perform functions with little or no human intervention. While initial adoption is focused mainly on non-clinical areas like scheduling and prior authorizations, experts predict that AI agents could eventually play a role in clinical decision-making, provided they meet rigorous safety and reliability standards.

Safety 300
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Precision Medicine: Becoming More Real With AI?

MedCity News

With technology advancements specifically in the field of AI, there is a clear line of sight in making it mainstream. Here are some of the ways AI is helping to accelerate the adoption of PM. The post Precision Medicine: Becoming More Real With AI? appeared first on MedCity News.

Medicine 345
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Metabolic Meds Startup Verdiva Launches With $411M and a Weekly Oral GLP-1 Drug

MedCity News

Verdiva Bios once-a-week oral GLP-1 drug is ready for Phase 2 testing. The drug, made with a proprietary technology that enables oral dosing, was licensed from Sciwind Biosciences. The post Metabolic Meds Startup Verdiva Launches With $411M and a Weekly Oral GLP-1 Drug appeared first on MedCity News.

Biopharma 278
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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What AI Can Do for Pharmacist Burnout

MedCity News

AI offers a number of immediate opportunities for pharmacies to change their operation through intelligent automation, freeing up pharmacists to provide their patient population with higher-value services like patient counseling and medication management. The post What AI Can Do for Pharmacist Burnout appeared first on MedCity News.

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Where Does AgeTech Investment Stand?: VCs Weigh Promise Against Payout

MedCity News

At Medicarians 2025, MedCity News Editor-in-Chief Arundhati Parmar explored the state of AgeTech venture capital with three investors. The panelists agreed that despite growing clear opportunities, the AgeTech market currently lacks the dedicated funding, proven business models and major success stories needed for it to take off. The post Where Does AgeTech Investment Stand?

Marketing 269
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Biopharma in 2025: Outlook for Obesity Meds, Drug Prices, Regulation & More

MedCity News

Metabolic medicines dominated life sciences headlines in 2024, a trend expected to continue into the new year. Other things to look for include more widespread adoption of artificial intelligence technologies and the IPO markets return to normal levels. The post Biopharma in 2025: Outlook for Obesity Meds, Drug Prices, Regulation & More appeared first on MedCity News.

Biopharma 311
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Biocompatible Nanoparticles: Tiny Antennae with Huge Potential for Brain-Computer Interfaces

MedCity News

To bridge the gap between invasive and non-invasive technologies, nanoscale materials, such as biocompatible nanoparticles, provide a promising alternative, allowing us to design materials at the scale of cellular systems and structures. The post Biocompatible Nanoparticles: Tiny Antennae with Huge Potential for Brain-Computer Interfaces appeared first on MedCity News.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.