Sat.Jul 20, 2024 - Fri.Jul 26, 2024

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Ipsen builds again, licensing Day One glioma drug

pharmaphorum

Ipsen has signed yet another portfolio-expanding deal – its fifth of the year so far – claiming rights outside the US to a drug for common brain cancer glioma from Day One Biopharmaceuticals.

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Enhertu stalls as AstraZeneca, Daiichi navigate 'harder yards' for ADC star

Fierce Pharma

Among AstraZeneca’s growth drivers with $5 billion or more in peak sales potential, the company is counting on Daiichi Sankyo-partnered Enhertu to chart new territory. | Among AstraZeneca's growth drivers with $5 billion or more in peak sales potential, the company is counting on Daiichi Sankyo-partnered Enhertu to chart new territory. And stalling sales underscore the challenges facing the HER2 drug.

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Revolutionising Drug Discovery: AI Advances with Insilico Medicine's PandaOmics.

Pharma IQ

Discover how AI is transforming drug discovery and the future of AI in pharmaceutical research.

Medicine 130
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NCPA, Providers File Lawsuit Against UHG Over Change Healthcare Cyberattack

MedCity News

The National Community Pharmacists Association and providers argued that Change Healthcare didn’t take the needed precautions against the cyberattack that happened earlier this year. The post NCPA, Providers File Lawsuit Against UHG Over Change Healthcare Cyberattack appeared first on MedCity News.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Agilent builds its CDMO arm with $925m Biovectra buy

pharmaphorum

Agilent has boosted its contract development and manufacturing organisation (CDMO) capacity with a $925 million deal to buy Biovectra, a Canadian provider of fill-and-finish services and active pharmaceutical ingredients (APIs).It's a statement of intent from Agilent, whose primary business is lab instrumentation and equipment, suggesting that it intends to grow the outsourcing side of its business, which is currently focused on the production of oligonucleotide and peptide medicines.

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Sinking prices for generic meds a major factor in US shortage crisis: report

Fierce Pharma

As lawmakers and industry groups seek to get a handle on U.S. | As lawmakers and industry groups seek to get a handle on U.S. drug shortages, a new white paper from German market analytics firm QYOBO supports the thesis that disproportionately low prices for generic medicines can make it difficult for drugmakers to keep supplies afloat.

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Fueled With $100M, Autobahn Therapeutics Gears Up for Depression Drug Clinical Trials

MedCity News

Autobahn Therapeutics’ platform technology enables small molecules to selectively hit targets in the brain. In addition to a lead program ready for Phase 2 testing in two types of depression, the startup has a preclinical molecule with potential applications in neuroinflammatory disorders such as multiple sclerosis. The post Fueled With $100M, Autobahn Therapeutics Gears Up for Depression Drug Clinical Trials appeared first on MedCity News.

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PBMs under the cosh at House hearing on drug pricing

pharmaphorum

The top three pharmacy benefit managers in the US felt the heat at a hearing of the House Oversight Committee, as lawmakers grilled executives over their business practices and accused them of monopolising the supply chain.

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With capacity upgrades ready to roll, Sanofi stands firm on blockbuster sales goal for RSV drug in 2024

Fierce Pharma

While manufacturing and supply hitches have troubled the rollout of Sanofi’s key respiratory syncytial virus (RSV) drug, the near-term expected approval of a pair of new filling lines is giving the | While manufacturing and supply hitches have troubled the rollout of Sanofi’s key respiratory syncytial virus drug, the near-term expected approval of a pair of new filling lines is giving the French pharma assurance that its AstraZeneca-partnered antibody Beyfortus can breach the billion-dollar thre

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How NVIDIA grew with the healthcare market instead of pushing into it

Pharmaceutical Technology

As the use of AI soared across healthcare, NVIDIA fit the bill in providing the necessary technology – and its stock tells the same story.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Healthcare’s Failure of AI Imagination

MedCity News

The dynamics of care delivery have already begun to shift, whether healthcare likes it or not. And it’s an opportunity to collaborate alongside healthcare consumers to shape what will be. The post Healthcare’s Failure of AI Imagination appeared first on MedCity News.

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Can Pfizer, Sangamo energise haemophilia A gene therapy?

pharmaphorum

There has been a gene therapy on the market for people with the bleeding disorder haemophilia A since 2022, but take-up has been very slow. Pfizer and Sangamo are hoping for a faster trajectory with their experimental treatment.The partners' one-shot giroctocogene fitelparvovec therapy has cleared a phase 3 trial, showing it was better than regular prophylaxis injections with Factor VIII (FVIII) replacement therapies at reducing bleeding episodes, and could now be heading for regulatory review.

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FDA blasts Indian CDMO Brassica for 'routine' data falsification, poor hygiene and more

Fierce Pharma

From flubbing data to performing aseptic processing with torn and stained gowns, Brassica Pharma’s recent warning letter from the FDA reads like a textbook example of what not to do when the U.S. | From flubbing data to performing aseptic processing with torn and stained gowns, Brassica Pharma’s recent warning letter from the FDA reads like a textbook example of what not to do when the U.S. regulator comes knocking at your facility.

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Study suggests targeting amyloid beta production could be promising in AD

PharmaTimes

The neurodegenerative disease is currently the most common cause of dementia

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How to Stay Competitive in the Evolving State of Martech

Marketing technology is essential for B2B marketers to stay competitive in a rapidly changing digital landscape — and with 53% of marketers experiencing legacy technology issues and limitations, they’re researching innovations to expand and refine their technology stacks. To help practitioners keep up with the rapidly evolving martech landscape, this special report will discuss: How practitioners are integrating technologies and systems to encourage information-sharing between departments and pr

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Earning Trust in Neurotech

MedCity News

By prioritizing user-centric design, responsible data practices, and evidence-based solutions neurotech companies can not only drive user adoption but also foster long-term brand loyalty. The post Earning Trust in Neurotech appeared first on MedCity News.

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NICE says Boehringer stroke drug 'could save millions'

pharmaphorum

NICE clears NHS use of Boehringer's clot-busting drug Metalyse for acute ischaemic stroke, saying it could 'save millions'

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Agilent Technologies lays out $925M to acquire Canadian specialty CDMO Biovectra

Fierce Pharma

After changing hands several times throughout the 2010s, Canadian specialty contract development and manufacturing organization (CDMO) Biovectra has agreed to fly the Agilent flag. | Agilent has revealed that it’s signed a definitive agreement to acquire Biovectra for $925 million through a mix of cash and debt financing. The deal is expected to close this year.

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Investing in Small Business Sales Training

Integrity Solutions

In an increasingly complex and competitive business world, small businesses often face unique challenges that can hinder their growth and success. One of the most critical areas where small businesses can gain a competitive edge is by investing in their teams’ development, particularly through sales training. Small business sales training is not just about learning how to sell more products or services; it’s about transforming the mindset of your sales team, enhancing the value they

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Neuro Drug Passed Up by Biogen Posts Positive Data for Ionis, Setting Stage for Phase 3 Test

MedCity News

Ionis Pharmaceuticals is looking ahead to a Phase 3 study for an antisense medicine it is developing to treat Angelman syndrome, a rare neurodevelopmental disorder with no FDA-approved therapies. Its main competition is an Ultragenyx Pharmaceutical drug set to begin pivotal testing later this year. The post Neuro Drug Passed Up by Biogen Posts Positive Data for Ionis, Setting Stage for Phase 3 Test appeared first on MedCity News.

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Linus Health grows in dementia with Together acquisition

pharmaphorum

Digital dementia detection specialist Linus Health has expanded its patient care focus with the acquisition of Together Senior Health.

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BeiGene CEO eyes biologics deals for new US innovation center in New Jersey

Fierce Pharma

HOPEWELL, NEW JERSEY—A new 42-acre campus in New Jersey gives BeiGene CEO John Oyler hope that the company can strike new partnerships in biologics. | A new 42-acre campus in New Jersey gives BeiGene CEO John Oyler hope that the company can strike new partnerships in biologics.

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AC Immune wins FDA fast track for Alzheimer’s vaccine candidate

Pharmaceutical Technology

JNJ-2056 is being investigated in the Phase IIb ReTain study which enrols participants who are yet to show Alzheimer’s symptoms.

FDA 95
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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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We Know Routine Screening Saves Lives – Why Is It Overlooked in Mental Health?

MedCity News

To make mental health screening a routine part of primary care, we need innovative solutions. Emerging technologies, particularly artificial intelligence (AI), are paving the way. The post We Know Routine Screening Saves Lives – Why Is It Overlooked in Mental Health? appeared first on MedCity News.

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Grünenthal buys Valinor and constipation drug for $250m

pharmaphorum

Pain medicine specialist Grünenthal has agreed to buy Valinor Pharma for $250m, getting control of Movantik for opioid-induced constipation

Medicine 105
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Amid Eylea clash, Roche's Vabysmo keeps climbing despite a slowdown in its momentum

Fierce Pharma

While Roche touted sales and market share increases for eye disease drug Vabysmo on Thursday, there is evidence of a slowdown of its momentum as it battles Regeneron and Bayer’s powerhouse Eylea fr | While Roche touted sales and market share increases for eye disease drug Vabysmo on Thursday, there is evidence of a slowdown of its momentum as it battles Regeneron and Bayer’s powerhouse Eylea.

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Johnson & Johnson submits sNDA for SPRAVATO to treat depression

Pharmaceutical Technology

Johnson & Johnson is seeking approval for SPRAVATO for treatment-resistant depression with the submission of an sNDA to the US FDA.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Patients Want Personalized Digital Experiences. Could a Modular Back End Help?

MedCity News

To personalize the patient journey, hospitals need a digital back end capable of delivering tailored experiences. Here’s how a composable digital experience platform (DXP) works and how it can help you offer multiple layers of personalization to meet your patient’s needs. The post Patients Want Personalized Digital Experiences. Could a Modular Back End Help?

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Study finds wearables deliver key insights in heart disease

pharmaphorum

Consumer wearables have shown a benefit when used to monitor treatment responses in patients with atrial fibrillation and heart failure.

Patients 108
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J&J's Texas two-step bankruptcy maneuver shut down again by appeals court

Fierce Pharma

Johnson & Johnson’s latest attempt to get a handle on its talc litigation using the controversial Texas two-step bankruptcy strategy has once again fallen flat after a federal appeals court rul | The ruling from the Third Circuit Court of Appeals came the night before claimants in the talc litigation were set to vote on a sweeping $6.48 billion settlement proposal from J&J.

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Sales Training Strategies: Overcome Challenges and Drive Success

Quantified

Executive Summary Mastering sales training strategies is crucial for overcoming challenges and driving success. Traditional sales kickoffs often fail to engage and prepare teams effectively. Modernizing events with interactive elements like AI role-playing scenarios, live product demos, and gamified training boosts engagement and retention.AI-driven personalized coaching addresses seller blind spots through targeted training and real-time feedback, leading to continuous improvement and higher su

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ABM Evolution: How Top Marketers Are Using Account-Based Strategies

In times of economic uncertainty, account-based strategies are essential. According to several business analysts and practitioners, ABM is a necessity for creating more predictable revenue. Research shows that nearly three-quarters of marketers (74%) already have the resources needed to build successful ABM programs.