Wed.Sep 07, 2022

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The current pharma business model is unsustainable

World of DTC Marketing

Wall Street wants growth, as do investors, but that may be impossible for pharmaceutical companies. In pharma, growth depends on new products with hefty price tags when over 80% of voters want lower costs for their prescription drugs. Biogen’s failure should be a warning to other pharma companies. They relied so much on a new drug that they tried to market a product with bad science behind it.

Pharma 210
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Conversational AI helps alleviate impact of nurse shortages

MedCity News

One organization piloted a smart speaker system in its spinal injuries unit. Over the course of four weeks, patients interacted with the automated assistant more than 5,000 times. Sixty-three percent of nurses on the unit found the pilot improved their ability to deliver and prioritize patient care.

Patients 132
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Trending Sources

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Bridge Bio will use Brainomix AI in lung fibrosis trial

pharmaphorum

Brainomix has reeled in another pharma partner for its artificial intelligence-powered biomarker software, used to track the performance of therapeutic interventions in clinical trials. South Korea’s Bridge Biotherapeutics has signed up to use the UK medtech firm’s e-ILD software package in a phase 2 trial of BBT-877, its experimental therapy for serious lung disease idiopathic pulmonary fibrosis (IPF).

Patients 113
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The divorce of care from health in healthcare: Reuniting American healthcare

MedCity News

The drive to “fix healthcare” is ingrained in our society. Politicians speak about it regularly, consumers struggle to understand it, and yet the “how” of fixing it is delivered with ambiguity and jargon. With increased urgency to improve healthcare, everyone is now laser focused on this topic. But, over time, the term “healthcare” itself has lost the part about care.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Surface Coating Rapidly Kills Pathogens, Lasts Months

Medgadget

A team at the University of Michigan has developed a coating for frequently touched surfaces that can rapidly kill a wide array of pathogens, including MRSA and SARS-CoV-2. The technology incorporates polyurethane that contains crosslinked compounds from essential oils with wide-spectrum anti-microbial action. The researchers fine-tuned the crosslinking process so that the oils were available to kill microbes but not sufficiently free to evaporate rapidly.

Food 112
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Arpeggio Biosciences rakes in $17M to measure the transcriptome

MedCity News

Arpeggio Biosciences raised $17 million in a Series A funding round led by Builders VC. The startup is focused on measuring the transcriptome — which refers to the full range of mRNA molecules expressed by an organism — to develop better therapeutics.

Biopharma 122

More Trending

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Unraveling the interplay of omicron, reinfections, and long Covid

MedCity News

Although omicron infections are proving milder overall than those caused by last summer’s delta variant, omicron has also proved capable of triggering long-term symptoms and organ damage. But whether omicron causes long covid symptoms as often — and as severe — as previous variants is a matter of heated study.

Biopharma 115
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India grants approval for Bharat Biotech’s intranasal Covid-19 vaccine

Pharmaceutical Technology

Indian company Bharat Biotech International has secured approval from Central Drugs Standard Control Organisation (CDSCO) under Restricted Use in Emergency Situation for its intranasal Covid-19 vaccine, iNCOVACC (BBV154), for usage in people aged 18 years and older. A recombinant replication-deficient adenovirus vectored vaccine, iNCOVACC has a prefusion stabilised spike protein and is claimed to be the first intranasal vaccine globally to obtain primary two-dose schedule approvals.

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CertifyOS raises $14.5M in Series A funds for credentialing automation platform

MedCity News

Provider intelligence platform CertifyOS recently raised $14.5 million in Series A funding, which it will use to strengthen its automation software for clinician credentialing, licensing and enrollment. The startup also announced it has received certification as a CVO from the National Committee for Quality Assurance.

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How to Distribute Content to Doctors (Plus, 7 Tips on Email Marketing to Doctors)

Healthcare Success

Welcome to step four of our “Marketing to Doctors” blog series. This comprehensive playbook is designed to help people in virtually every sector (e.g., healthcare businesses, device and supply companies, SaaS, etc.) market their products and services directly to doctors, physicians, surgeons, and other healthcare professionals. If you haven’t read steps 1-3, I highly recommend doing so.

Doctors 101
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Analyzing CVS Health’s $8B buy: There’s no place like home

MedCity News

CVS Health reportedly beat out other big names, including Amazon and UnitedHealth Group. Signify Health has a network of more than 10,000 clinicians in all 50 states and a nationwide value-based provider network.

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AI Device Monitors Breathing to Diagnose Parkinson’s

Medgadget

Researchers at MIT have developed an AI system that can diagnose Parkinson’s disease and track its progression, simply by monitoring someone’s breathing patterns as they sleep. The device looks like an internet router and can be mounted on the wall in a bedroom. It emits radio waves and then a neural network analyzes the reflected waves to assess breathing patterns.

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The patient privacy factor in clinical trials

MedCity News

In the first quarter of 2022, my personal life converged with my work life concerning […].

Patients 132
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EU regulators release new workplan for accelerating clinical research

European Pharmaceutical Review

The 2022-2026 workplan of the initiative Accelerating Clinical Trials in the EU ( ACT EU ) has been published by the European Commission (EC), Heads of Medicines Agencies (HMA) and European Medicines Agency (EMA). Launched in January, ACT EU aims to transform how clinical trials are initiated, designed and run, building off of the Clinical Trials Regulation (CTR) and Clinical Trials Information System (CTIS) which became applicable in the same month.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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What tirzepatide means for the fight against obesity

MedCity News

For individuals who have tried and failed to find success with diet and exercise alone, we now have one more weapon and one more reason for hope.

Biopharma 104
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Gilead claims first CAR-T approval for leukaemia in older adults

pharmaphorum

Gilead Sciences’ Kite Pharma unit has carved out a niche for its CD19-targeted CAR-T therapy Tecartus in acute lymphoblastic leukaemia (ALL) in Europe, free of direct competition from arch-rival Novartis. The European Commission has approved Tecartus (brexucabtagene autoleucel) for adults aged 26 and over with relapsed or refractory B-cell precursor ALL, a patient population not covered by the label for Novartis’ CD19 CAR-T Kymriah (tisagenlecleucel), which covers paediatric and youn

Sales 91
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Woman of the Week: Foresite Capital’s Cindy Mesaros

PharmaVoice

The longtime marketing pro details her fascinating career journey and how she’s positioning early stage health companies to thrive.

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Evolving real-time dissolution prediction and product release

European Pharmaceutical Review

Researchers have developed a deterministic permeation model (DPM) that predicts the in vitro release profile of an active pharmaceutical ingredient (API) embedded in hydroxypropyl-methylcellulose (HPMC) matrix tablets. The model, based on Raman spectra, has the potential to process in real-time data yielded by process analytical technology (PAT) sensors, which could allow it to be utilised for real-time release testing (RTRt).

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Ceriz Tablet Uses, Benefits & Side Effects

Teachntest

Advertisement Ceriz Tablet Uses, Benefits & Side Effects PRODUCT INTRODUCTION Ceriz Tablet belongs to the class of drugs known as antihistamines. It is used to treat a range of allergic conditions, including hay fever, conjunctivitis, certain skin reactions, and insect bite and sting reactions. It relieves runny nose, watery eyes, sneezing, and itching.

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10 Leadership Mistakes Every Medical Sales Rep Should Avoid

MedReps

Working as a medical sales rep means you’ll have at least one direct team leader you’ll need to report to on a regular basis. These leaders, although quite knowledgeable about the industry, aren’t infallible. In fact, they often make some common leadership mistakes that can hurt the team’s overall work performance. Are you the team leader of your medical sales team?

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Hiring and Training a Medical Sales Team with Aeroflow Healthcare

Map My Customers

A well-developed hiring and training program is critical when building a high-performing medical sales team. Your company’s success is only as strong as the performance of your sales reps. This is true no matter what type of company you are. But, as Map My Customers ’ Senior Enterprise Account Executive JT Rimbey describes, “hiring the right people can be such a challenge, to ensure not only the right company cultural fit but also a fit for the types of customers and selling

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Brainomix and Bridge Biotherapeutics enter artificial intelligence partnership

PharmaTimes

Link up will utilise Brainomix’s AI software for the assessment of idiopathic pulmonary fibrosis

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

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Accelerating Time-to-Insight Throughout the BioPharma Lifecycle

PharmaTech

Innovation is driven through a strong digital backbone.

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UCB reveals new Bimzelx ‘complete skin clearance’ data

PharmaTimes

Positive data represents a boost for patients with moderate to severe plaque psoriasis

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Health system leaders: Referral optimization needs to be part of your value strategy

Clarify Health

Among health systems predominantly operating within the traditional fee-for-service (FFS) context and those engaging in risk-based contracts, uncovering opportunities to drive higher-value care is a constant refrain. Health systems are increasingly being measured on quality metrics by payers seeking to tailor narrow networks and by consumer preferences driven by Leapfrog and the Centers for Medicare & Medicaid Services (CMS) Star Ratings.

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Roche takes another punt on IL-2 in cancer with Good takeover

pharmaphorum

Despite setbacks for projects trying to harness the power of the cytokine interleukin-2 (IL-2) as a cancer therapy, there are still plenty of players on the field – and Roche has just joined their ranks. The Swiss pharma group has agreed to buy Seattle-based biotech Good Therapeutics and its preclinical-stage PD-1-regulated IL-2 receptor agonist programme for $250 million upfront, with undisclosed milestone payments on offer tied to development, regulatory, and commercial objectives.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Health system leaders: Referral optimization needs to be part of your value strategy

Clarify Health

Among health systems predominantly operating within the traditional fee-for-service (FFS) context and those engaging in risk-based contracts, uncovering opportunities to drive higher-value care is a constant refrain. Health systems are increasingly being measured on quality metrics by payers seeking to tailor narrow networks and by consumer preferences driven by Leapfrog and the Centers for Medicare & Medicaid Services (CMS) Star Ratings.

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The Increasing Trend of Native Advertising in Healthcare

LEVO Health

With the rise of digital media, healthcare marketers are looking for new ways to reach consumers and healthcare providers (HCPs). For the past two years, there has been an upward trend in incorporating native advertising into healthcare marketing strategies. Native advertising can now be seen in nearly every healthcare industry, with pharma, hospitals, health systems, and regional service providers using this tactic to better reach their audiences.

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Fireside Chat with Robert Kaul, Founder, CEO & President of Cloud DX

Impetus Digital

Register for Impetus’ upcoming live webinar on September 21, 9 – 10 AM ET: A Fireside Chat with Robert Kaul, Founder, CEO & President of Cloud DX. About the webinar. Robert Kaul , Founder, CEO & President of Cloud DX , will sit down with Natalie Yeadon , Co-founder & CEO of Impetus Digital , in this live episode of Healthcare Goes Digital.

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COVID-19 health concern decreased in August: Poll

Pharmaceutical Technology

The health concern over COVID-19 in August 2022 decreased averaging at 22.3%, compared to 27.7% recorded in July 2022 , shows the COVID-19 concern index, which is measured by responses to an ongoing poll Verdict launched in March 2020. The poll has been tracking how the concerns over coronavirus have been changing over time. The poll asked how concerned the respondents were about the spread of coronavirus and included five options to choose from - very concerned, slightly concerned, neither conc

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The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.