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mRNA non-vaccine therapeutics to generate $2 billion by 2028

European Pharmaceutical Review

According to GlobalData’s recent report , a total of five marketed messenger RNA (mRNA) non-vaccine products by 2028 will generate over $2 billion, generated by the approval of pipeline agents. billion during 2028.

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Handling HPAPIs safely – what does it take?

European Pharmaceutical Review

Based on the latest report and data, HPAPI market size is expected to reach $32 billion by 2028. Biotechs working with early-stage NCEs must adopt a conservative approach to prioritise safety for their HPAPIs in discussions with contract development and manufacturing organisations (CDMOs) and other scientific partners.

Safety 91
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Happitech launches smartphone app for cardiac researchers

pharmaphorum

The digital health market is being driven by expansion of digital connectivity, declining cost of sensors and other technology components, and an increase in patient engagement, and is predicted to reach a value of $450 billion by 2028, according to the company.

Safety 84
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High risk, high reward – the future of CAR-T therapy in CLL

Pharmaceutical Technology

According to GlobalData’s analyst consensus forecast, Yescarta is expected to reach peak sales of $1.8bn in 2028, and Kymriah is expected to reach sales of $686m in the same year. Autologous CAR-T agents are now becoming the standard of care for patients in the third line and later settings, providing lucrative returns for these agents.

Safety 111
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More big wins for the AstraZeneca-Daiichi Sankyo collaboration

Pharmaceutical Technology

Enhertu has already achieved regulatory approval as a second-line therapy for metastatic or recurrent HER2-positive breast cancer, as well as HER2-positive gastric or gastroesophageal junction adenocarcinoma, with annual sales for these indications alone expected to exceed $1.3bn by 2028.

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Accelerating AMR vaccine development

European Pharmaceutical Review

While regulatory support, such as breakthrough therapy designations, can help in this regard, there is a critical need to collaborate with regulatory agencies to agree efficient clinical trial designs that maintain appropriate demonstration of safety and efficacy. AMR has the potential to be just as devastating for the world as COVID-19.

Safety 98
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#ASH22: Pirtobrutinib emerges as an option for Richter’s Transformation

Pharmaceutical Technology

In the pirtobrutinib safety cohort, only 2.6% GlobalData’s consensus analyst forecast database projects peak sales for pirtobrutinib to reach $892 million by 2028, and $4.8 Only 75 patients were evaluable for response, of which ten underwent a complete response, and 29 a partial response, resulting in a 52% overall response rate (ORR).

FDA 59