pharmaphorum

DECEMBER 23, 2022

There’s been huge progress in treatments for blood cancer in recent years – but drawbacks of expensive CAR-T cell and injected antibody therapies have led drug developers to look at novel oral therapies as patient-friendly alternatives. Results suggest durable epigenetic re-wiring and provide rationale for intermittent clinical dosing.

Side effects 52

Side effects Patients Medical Medicine 52

Pharmaceutical Technology

NOVEMBER 9, 2022

On November 2, the Institute for Clinical and Economic Review (ICER) released its updated evidence aimed at measuring the clinical effectiveness and cost of the two haemophilia gene therapies. CSL Behring has a commercialisation and license agreement to develop EtranaDez. million price tag. million ($1.8

Safety 111

Safety Pharmaceutical Patients Medicine 111

Pharmaceutical Technology

DECEMBER 15, 2022

Prior to the development of Camzyos and aficamten, obstructive HCM has not been the target of clinical trial development, so these two therapeutics would benefit a neglected patient population. of sales in 2021 and 2031 respectively. The second highest contributing market is APAC, generating 33.2%

Marketing 52

Marketing Sales Healthcare Healthcare 52

pharmaphorum

JANUARY 9, 2023

Zolgensma meanwhile is now approved in 45 countries, with over 2,500 patients treated globally across clinical trials, managed access programs, and in the commercial setting. ” Zolgensma is one of the most expensive therapies available, with a price tag of around $2.1

Side effects 115

Side effects Patients Management Marketing 115

PM360

APRIL 22, 2024

From defining the target product profile to shaping clinical endpoints and devising asset strategies to crafting scientific narratives, the value of Medical Affairs permeates every aspect of product development. Today, teams are indispensable strategic partners, deeply involved in crafting the very foundation of a product’s journey.

Medical 52

Medical Healthcare Healthcare Education 52

Pharmaceutical Technology

JUNE 29, 2022

This year has already been eventful when it comes to the development of therapies for rare diseases. Most, if not all, of these therapies used the FDA’s Orphan Drug Designation to aid their development plans. Additionally, pricing and access for rare disease therapies continue to be scrutinized closely.

Food and Drug Administration 98

Food and Drug Administration FDA Marketing Pharmaceutical 98

European Pharmaceutical Review

AUGUST 24, 2022

In total, there are 14 approved ADCs on the global market, all for oncology indications, and over 140 ADCs currently in clinical development. Early ADC developments centred on using cytotoxins with the highest potency together with limited linker designs. cancer agent or disease-relevant toxin. necks inhibiting these first?generation

Engineering 82

Engineering Side effects Marketing Patients 82

Pharmaceutical Technology

MAY 2, 2023

Although a subset of patients derives long-term benefits from IO therapies, a high percentage of patients still fail to respond or develop resistance to IO therapy. IO therapies come with a hefty price tag, with ICI therapies in the US typically exceeding $100,000, while cell therapies can exceed $400,000.

Physicians 52

Physicians Marketing Patients Manufacturing 52

pharmaphorum

AUGUST 21, 2022

NMDA antagonist dextromethorphan is an ingredient found in cough syrups, while bupropion is an established antidepressant that was originally developed by GSK and sold as Wellbutrin. In this product, bupropion is designed to increase levels of dextromethorphan in the blood and extend its half-life.

FDA 93

FDA Marketing Pharma Sales 93

Pharmaceutical Technology

JANUARY 17, 2023

Despite its high price tag, bimagrumab’s unique features set it apart from currently marketed therapies. The post Versanis’ bimagrumab, first-in-class obesity therapy, enters Phase IIb of development appeared first on Pharmaceutical Technology.

Marketing 52

Marketing Patients Safety Pharmaceutical 52

PM360

NOVEMBER 12, 2023

This emotional intelligence can revolutionize marketing strategies and product development, enabling companies to tailor their offerings more effectively and empathetically.” One life science corporation leveraged real-world data to conduct a study based on a hypothesis that people were getting lung scans (e.g.,

Marketing 59

Marketing Media Patients Healthcare 59

Pharmaceutical Technology

APRIL 13, 2023

Two gene therapies up for approval this year for sickle cell disease could be cost effective in some cases at a $2 million price point, based on a draft evidence report published by the Institute for Clinical and Economic Review (ICER).

Healthcare 59

Healthcare Healthcare Pharmaceutical FDA 59

pharmaphorum

JULY 25, 2022

The drug in a number of clinical trials alone or in combination with other therapies, including a phase 3 study (MajesTEC-3) alongside Darzalex in patients who have received between one and three prior lines of therapy including a proteasome inhibitor and lenalidomide.

Medicine 52

Medicine FDA Recruitment Patients 52

pharmaphorum

JANUARY 31, 2023

Another factor that impacts trust in pharmaceutical companies is the discrepancy between the efficacy of medications in controlled clinical trials and their effectiveness in real-world use. Given the high price tags placed on many medications, it’s easy to understand why patients often feel that they are being taken advantage of.

Patients 52

Patients Pharma Side effects Education 52

Pharmaceutical Technology

APRIL 5, 2023

But access to these treatments continues to remain limited due to high price tags and variable availability across regions. This includes the first potential approval of a CRISPR-based gene therapy called exa-cel , which is developed by CRISPR Therapeutics and Vertex Pharmaceuticals.

Food and Drug Administration 59

Food and Drug Administration Engineering Patients Education 59

Healthcare Success

JULY 25, 2022

While market disruptors such as Telehealth and other retail clinics provide communities with more care options, they also drive higher staffing demands on an already small pool of candidates. He cautioned, "as we're developing more ways to connect with people, you can spread your efforts really thin."

Healthcare 100

Healthcare Healthcare Marketing Doctors 100

Healthcare Success

JULY 11, 2022

The development and subsequent launch of Google Analytics 4 (GA4) in October 2020 was spurred by a 2018 ruling of Europe’s General Data Protection Regulation (GDPR) , the strictest data privacy and security law in the world. Your marketing team can use these insights to develop more effective communication strategies.

Healthcare 95

Healthcare Healthcare Patients Marketing 95

Healthcare Success

MARCH 28, 2023

These specialists include Account managers SEO strategists and analysts Content strategists and top-tier copywriters Technical SEO experts Developers Social media specialists Building and maintaining fantastic SEO results requires true expertise and ongoing management. For illustrative purposes, let’s pretend you need heart surgery.

Competition 59

Competition Engineering Consulting Specialization 59

Pharmaceutical Technology

MARCH 22, 2023

The pharmaceutical industry began using radio frequency identification (RFID) tags in the early 2000s. Pfizer was the first to use the tech, adding RFID tags to track a Viagra (sildenafil) shipment circa 2006. As computing has developed in the past decade, so has the potential to store and use information in the cloud.

Food and Drug Administration 105

Food and Drug Administration Electronics Pharma FDA 105

Rep-Lite

MARCH 21, 2024

Medical sales representatives are healthcare professionals who promote medical equipment, pharmaceuticals, or services to hospitals, clinics, and physicians. Rep-Lite was created to provide top sales, clinical, and service talent to medical companies. There are rungs and each comes with both a price tag and an incentive.

Medical sales 52

Medical sales Medical sales reps Medical Sales 52

pharmaphorum

NOVEMBER 16, 2022

The advancements made in drug development over the last decade have seen the arrival of a number of treatments that offer one-time cures and more effective therapies for conditions in smaller patient populations. However, with a price tag of €1.58 How to navigate the new climate. At more than $2.1 million.

Medicine 127

Medicine Marketing Healthcare Healthcare 127

Copyright Clearance Center

NOVEMBER 7, 2023

. – CCC , a pioneer in voluntary collective licensing, advancing copyright, accelerating knowledge, and powering innovation, announces Clinical Trial Registries, a new data connector for customers of the cloud-based software solution RightFind Navigate. clinical trials through the connector to ClinicalTrials.gov.

Management 115

Management 115

Pharmaceutical Technology

JUNE 21, 2023

The high price tag may be hard to defend , but with lifetime treatment costs for haemophilia B reaching as high as $23m for some, the single-dose treatment could prove far more cost-effective. Despite this, the Institute for Clinical and Economic Review (ICER) claimed that a fairer price would be in the region of $2.9m.

Patients 98

Patients Food and Drug Administration Engineering Sales 98

European Pharmaceutical Review

MAY 11, 2023

In this Q&A, Dr Sitra Tauscher-Wisniewski, Vice President of Clinical Development & Analytics of Novartis Gene Therapies elaborated on the key findings and discussed the importance of collaboration in fast-tracking access to gene therapies such as Zolgensma. 1 This is assuming a $1M price tag for all gene therapies.

Food and Drug Administration 70

Food and Drug Administration Government Healthcare Healthcare 70

PM360

APRIL 7, 2023

It’s never too early in the research and development (R&D) process to identify and measure a product’s projected clinical outcomes in order to meet the needs and expectations of payers and healthcare professionals (HCPs) who are the final arbiters of a product’s commercial success. million for the new hemophilia gene therapy.

Manufacturing 52

Manufacturing Marketing Patients Safety 52

European Pharmaceutical Review

NOVEMBER 10, 2022

The biological characterisation of complex medicines is fundamental to translate these novel therapeutics and associated drug delivery technologies into the clinic; to understand the interplay with biological systems and to evaluate new formulations?. Three reasons complex medicines fail at the late stages of development.

Medicine 96

Medicine Distribution Engineering Electronics 96

European Pharmaceutical Review

JULY 11, 2022

The novel coronavirus vaccine has been developed at Caltech and The University of Oxfor d. Funding of up to $30 million will support vaccine design, its development through Phase I trials and regulatory activities. . The pre-clinical research published in Science demonstrates that the mosaic?8 8” nanoparticles. . The mosaic?8

Manufacturing 93

Manufacturing Engineering Leads Medicine 93

Map My Customers

AUGUST 2, 2022

Surgical Equipment Sales - This type of rep will be selling specialized surgery equipment that often comes with a high price tag. It identifies the changes in the medical field and enables you to develop and maintain a solid game plan for success. So, make the effort to try and capitalize on this opportunity when it is available.

Medical sales reps 79

Medical sales reps Medical sales Sales Medical 79

PM360

SEPTEMBER 7, 2023

Then onto Tuan Vu, MD, Professor of Neurology, Director, Neuromuscular Division, EMG Laboratories, and ALS Clinic, Department of Neurology University of South Florida, who discussed the global clinical trial. We also put big pull tags on the little pouches that held the items.

Patients 105

Patients Pharma Education Doctors 105

Pharmaceutical Technology

JANUARY 27, 2023

Sanofi’s eligibility requirements follow a similar model to Pfizer’s previous programs, with refunds being dependent on lack of clinical outcome in patients. With these therapies, there is the possibility of there being no clinical benefit and an emergence of adverse events. Do we know how to identify the right patients?”

Patients 52

Patients Pharmaceutical Manufacturing Healthcare Provider 52

pharmaphorum

OCTOBER 4, 2022

Central to the initiative is the aim to gather data from willing participants that can provide greater insights into cancer development and treatment over time. The objective is to gather patient biospecimens longitudinally to understand how patients react to treatments and how cancer develops over time.

Electronics 97

Electronics Patients Management Insurance 97

pharmaphorum

SEPTEMBER 30, 2022

While some narrative text is still required, auto-population of clinical data into tables eliminates the need for substantial quality control actions. Building documents from components also reduces review cycle time frames. Fillable metadata is next added to the templates. Donald Palmer, Senior Director, Regulatory Affairs, IQVIA.

Management 52

Management Pharmaceutical Marketing Electronics 52

Medico Reach

AUGUST 30, 2022

However, developing a profitable marketing strategy is even more challenging. Carilion Clinic’s YESMAMM Campaign. Carilion Clinic developed the YESMAMM marketing initiative in the Roanoke Valley of Virginia. Anyone could post a query using the tag YESMAMM, and they would get an immediate response.

Healthcare 52

Healthcare Healthcare Marketing Medical 52

Evolve Your Success

JULY 19, 2022

You have to develop this skill already nowadays. It’s for you to develop that ability to copyright, persuade, and think through, “What am I going to put in this to get it opened and for somebody to take action on it? From now, you have to start developing the discipline of self-education. It depends on your goals.

Medical sales 52

Medical sales Media Sales Education 52

Evolve Your Success

JUNE 13, 2023

You think about a dermatologist or a PA diagnosed a melanoma in their private practice or their clinic. They just want the name tag. That develops over time compared to somebody who’s getting in. I was the guy that put his name tag, “I want to prove that I belong.” I’m riding bikes with her and playing tag.

Sales 52

Sales Medical sales Medical Doctors 52

European Pharmaceutical Review

DECEMBER 27, 2023

2,3 Clinical implementation of CAR T-cell technology requires a reproducible T-cell manufacturing platform, which necessitates effective gene-transfer tools and T-cell culture conditions. 6-8 Clinical recommendations also change. This is in addition to its considerable price tag.

Manufacturing 83

Manufacturing Food and Drug Administration Patients Pharma 83

Evolve Your Success

DECEMBER 27, 2022

She helped develop that brand in January 2021. I’m non-clinical at this point. The surgeon’s busy covering the case, and you’re telling me that you even created an avenue to invite representatives that had taken the time to develop a relationship with you to sell to you. This led her to be in First Case Podcast.

Medical sales 52

Medical sales Medical sales reps Sales Medical 52