Sat.Nov 25, 2023 - Fri.Dec 01, 2023

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Pfizer site in Connecticut in line for layoffs amid $3.5B cost-cutting campaign

Fierce Pharma

With layoffs hitting employees on both sides of the Atlantic, Pfizer’s $3.5 billion cost-cutting spree has kicked it into high gear this month. | The company's Groton, Connecticut, research site is the latest to fall victim to job cuts as part of Pfizer's massive $3.5 billion cost-cutting mission, following layoffs across the U.S. and the U.K.

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AWS, Hoppr Launch Model to Accelerate Generative AI Tools in Medical Imaging

MedCity News

At RSNA 2023, AI startup Hoppr announced that it teamed up with AWS to launch a new foundation model. The product, named Grace, is a B2B model designed to help application developers build better AI solutions for the medical imaging field — and to build them more quickly.

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Doctor Marketing: How to Integrate Doctors Into Your Marketing Programs

Healthcare Success

Doctors are central to the success of virtually every multi-location healthcare practice and health system we work with. Moreover, today’s doctor partners have strong opinions about marketing and growing their locations within the larger business. Some of the hospitals and multilocation practices that engage our agency have doctors, executives, investors, and other stakeholders aligned around their brand strategy and marketing plan.

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Don’t Get Distracted By AI, Instead Focus on Intellectual Property

PharmExec

Artificial intelligence is making it quicker to get drug candidates to the clinic, but it isn’t addressing the fundamental need to marry the right candidate and the right target to the right disease.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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FDA investigates 'serious risk' of secondary cancer following CAR-T treatment

Fierce Pharma

In a blow to CAR-T therapies, the FDA is investigating a “serious risk” of patients developing new cancers after treatment with these highly efficacious oncology drugs. | In a blow to CAR-T therapies, the FDA is investigating a “serious risk” of patients developing new cancers after treatment with these highly efficacious oncology drugs.

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Nvidia Launches Cloud-Based APIs to Accelerate AI Deployment in Medical Imaging

MedCity News

At RSNA 2023, Nvidia launched new set of cloud-based APIs designed to speed up the creation and deployment of specialized AI models in the medical imaging field. The new offering is a cloud-native extension to Nvidia’s Monai framework, which is its open-source framework for medical imaging AI.

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More Trending

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FDA Investigating Risk of Secondary Cancers in Patients Administered CAR T-Cell Therapy

PharmExec

The FDA will investigate all currently approved CAR T-cell treatments, as well as BCMA-directed and CD19-directed genetically modified autologous CAR T-cell therapies, for the risk of secondary T-cell malignancies.

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Pfizer takes Poland to court over alleged missed COVID-19 vaccine payments

Fierce Pharma

As the pandemic eased earlier this year, officials in Poland became vocal critics of the financial obligations laid down by Pfizer’s large vaccine supply pact with the European Union. | As the pandemic eased earlier this year, officials in Poland became vocal critics of the financial obligations laid down by Pfizer’s large vaccine supply pact with the European Union.

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Why Generative AI Threatens Hospital Cybersecurity — and How Digital Identity Can Be One of Its Greatest Defenses

MedCity News

While more generative AI tools are becoming available in healthcare for diagnostics and patient communication, it is important for clinicians and healthcare staff to be aware of the security, privacy, and compliance risks when entering protected health information (PHI) into a tool like ChatGPT.

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Itsy Bitsy Teenie Weenie Yellow Polka Dot Bikini: How Male Bias in the Lab Has Consequences for Female Outcomes

PM360

No one wants to deal with a hormonal mouse. When I was a graduate research assistant, I studied the impact of enriching a human’s environment on cognition. My research was conducted on mice, but not every type of mouse. In fact, a large portion of the mouse population was purposefully left out of the study. The reason was simple: female hormones could potentially affect our data.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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FDA Priority Review Granted to Keytruda/Padcev Combo for Locally Advanced, Metastatic Urothelial Carcinoma

Pharmaceutical Commerce

In clinical trials, Keytruda plus Padcev lowered the risk of disease progression or death by 55% compared with chemotherapy in adult patients with locally advanced or metastatic urothelial carcinoma.

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Amgen expands pact with Amazon to usher drug manufacturing into the AI era

Fierce Pharma

Seeking to identify ways to improve the discovery and production of medicines, Amgen is expanding its partnership with tech giant Amazon. | Amgen is growing its decade-old collaboration with Amazon Web Services—a widely used cloud platform—to create generative artificial intelligence that the companies aim to use to increase the manufacturing throughput of pharmaceuticals.

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Expert: The Rumored Humana/Cigna Combination Makes Sense

MedCity News

With Cigna mostly focused on the commercial market and Humana mostly focused on the Medicare Advantage market, the rumored combination rumors check out, according to one industry expert.

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Strategies for Combination Therapy in Oncology: Part Two – Working with the “Status Quo”

PM360

This is the second article in a three-part series examining the commercial dynamics surrounding combination therapy in oncology across the U.S. and Europe. In this article, we investigate strategies that manufacturers could consider to optimize pricing and access opportunities for their combinations in today’s environment. (You can find part one here.

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How to Stay Competitive in the Evolving State of Martech

Marketing technology is essential for B2B marketers to stay competitive in a rapidly changing digital landscape — and with 53% of marketers experiencing legacy technology issues and limitations, they’re researching innovations to expand and refine their technology stacks. To help practitioners keep up with the rapidly evolving martech landscape, this special report will discuss: How practitioners are integrating technologies and systems to encourage information-sharing between departments and pr

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AbbVie agrees $10 billion oncology acquisition

European Pharmaceutical Review

AbbVie has agreed to acquire ImmunoGen and its first-in-class antibody-drug conjugate (ADC) ELAHERE ® (mirvetuximab soravtansine-gynx), for a total of approximately $10.1 billion. The antibody-drug conjugate is the first to be approved for platinum-resistant ovarian cancer (PROC) and show meaningful survival benefit for this form of the disease. As a folate receptor alpha (FRα) with a maytansinoid payload DM4, a potent tubulin inhibitor, the biologic medicine offers expansion opportunities in e

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AbbVie pays $10B to acquire ImmunoGen, doubling down on red-hot ADC cancer field

Fierce Pharma

The sizzling antibody-drug conjugate (ADC) field is at the center of another major life sciences deal. | The sizzling antibody-drug conjugate field is at the center of another major life sciences deal. Hoping to redeem itself following the epic Rova-T failure, AbbVie is shelling out $10.1 billion in cash to acquire ImmunoGen, maker of the ovarian cancer treatment Elahere.

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Practice Risk Assessment: Do You Know What Your Patients Are Taking?

MedCity News

By revisiting practice workflows to implement more strategic habits of communication and documentation, clinicians can promote positive outcomes and mitigate practice liability risks at a time when patients maybe accessing care from myriad sources, some online.

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Revolutionizing Pharmacovigilance with Proactive Signal Detection

PM360

Up to now, drug safety teams have relied primarily on reactive reporting systems for pharmacovigilance (PV) or real-world drug safety monitoring. The signals, generally delivered through individual case safety reports (ICSRs), require significant time and effort to uncover, potentially delaying detection and negatively impacting patient safety. Most traditional signal detection methods focus on disproportionality, meanwhile calling attention to higher-than-expected correlations between the suspe

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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AbbVie agrees $10.1bn deal to buy ImmunoGen

pharmaphorum

AbbVie has moved to shore up its pipeline following the loss of patent protection for its top-selling drug with a $10.1 billion deal to buy ImmunoGen and its marketed ovarian cancer drug.

Marketing 101
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Gilead cuts 7% of staff at Kite Pharma unit as 'refreshed business strategy' introduced

Fierce Pharma

Gilead Sciences' Kite Pharma cell therapy unit is undergoing a business review that will result in layoffs to about 7% of the organization’s workforce. | Gilead’s Kite Pharma cell therapy unit is undergoing a business review that will result in layoffs to about 7% of the organization’s workforce. In a letter sent to staff this week that was obtained by Fierce Biotech, Kite Pharma Executive Vice President Cindy Perettie previewed a “refreshed business strategy” that would better align the un

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PCORI Pours $80.5M Into Research On Maternal Health Inequities

MedCity News

The Patient-Centered Outcomes Research Institute announced that it is funding four studies focused on reducing maternal health inequities. The studies all leverage partnerships with community organizations.

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Genentech’s Chief Marketing Officer Talks Marketing’s New Role and Data-Driven Content

PM360

I recently sat down with Erica Taylor, PhD, Vice President and Chief Marketing Officer at Genentech, to talk about the future of biopharma marketing and creating more meaningful content. In Erica’s role, she sets the vision, strategic enterprise leadership, and direction for the marketing function at Genentech, covering the company’s full commercial portfolio.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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How to succeed in biotech: A serial entrepreneur’s tips for surviving tough times

PharmaVoice

John Mulligan, founder of biotechs like Good Therapeutics and Bonum Therapeutics, discusses how biotechs can thrive when the market is against them.

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Novo Nordisk keeps GLP-1 expansion spree rolling with $2.3B manufacturing upgrade in France

Fierce Pharma

After plotting $6 billion in production upgrades earlier this month, Novo Nordisk’s CEO Lars Fruergaard Jørgensen suggested the expansion outlay was just the start. | After plotting $6 billion in production upgrades earlier this month, Novo Nordisk’s CEO Lars Fruergaard Jørgensen suggested the expansion outlay was just the start. Now, some three weeks later, he’s putting his company’s money where his mouth is.

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Philips Launches New Cloud-Based PACS & Unveils Mobile MRI System

MedCity News

Two of Philips’ most notable RSNA announcements were that its new cloud-based PACS is available and that its helium-free mobile MRI system will soon be deployed. More than 80 sites across the U.S. and Latin America have already migrated to Philips’ new PACS, and its mobile MRI system will be traveling to various cities next year.

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The Promise of Generative AI in Mitigating Bias in Continuing Medical Education

PM360

Continuing medical education (CME) is a top priority for healthcare providers in order to maintain their medical licensure, broaden and update their clinical knowledge, hone their skills, feed their curiosity, and ensure patients receive the best care and outcomes. Education companies that develop content have a list of considerations to meet when creating learning materials.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Acquisition deal to back European biosimilars market

European Pharmaceutical Review

Biocon Biologics Ltd has successfully completed integration of Viatris’ biosimilar business in 31 European countries. Following the acquisition of substantially all global biosimilar business of Viatris in November 2022, and the related integration of over 70 emerging market countries in July 2023 and North America in September 2023, now that Viatris’ biosimilars operations have fully transitioned to Biocon Biologics Ltd in Europe, the company declared that this “represents another significant m

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Pharma's Q3 growth rankings: GLP-1 drugs from Eli Lilly, Novo Nordisk were once again the big story

Fierce Pharma

Eli Lilly’s fortunes have turned quickly. | It was the second straight quarter where the overwhelming success of blood sugar regulating treatments were the dominant story in the biopharma industry. Eli Lilly and Novo Nordisk delivered the highest revenue gains, at 38% and 29%, respectively.

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FDA Probes New Cases of Cancer That May Stem From Cancer Cell Therapies

MedCity News

CAR T-therapies for cancer are now under tighter FDA scrutiny as the agency opens an inquiry regarding reports that some patients who received these cell therapies went on to develop new cases of cancer. The FDA said benefits of these therapies still outweigh their risks, but it is evaluating the need for regulatory action.

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Early Involvement, Better Outcomes: Bridging the Gap Between Clinical and Marketing Teams

PM360

I started my Insights career at a medical devices division of one of the world’s largest pharmaceutical companies. A significant shake-up at the company marked the start of my tenure: a newly appointed CEO with a consumer-packaged goods (CPG) background introduced a new Chief Marketing Officer (also from CPG) and an influx of global marketers from renowned companies such as P&G, Kraft, and Coca-Cola.

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ABM Evolution: How Top Marketers Are Using Account-Based Strategies

In times of economic uncertainty, account-based strategies are essential. According to several business analysts and practitioners, ABM is a necessity for creating more predictable revenue. Research shows that nearly three-quarters of marketers (74%) already have the resources needed to build successful ABM programs.