Tue.Jul 05, 2022

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Getting an Rx does not address health problems

World of DTC Marketing

Imagine a medicine that reduced the death rate of breast cancer and risk of recurrent breast cancer by 50% lowered the risks of colon cancer and type 2 diabetes by two-thirds, and those of heart disease, hypertension, and Alzheimer’s’ disease by 40%. On top of that, it can be as effective as antidepressants or cognitive behavioral therapy in countering depression.

Insurance 200
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Healthcare leaders are optimistic about metaverse disruption, report says

MedCity News

The metaverse has significant potential to disrupt traditional healthcare delivery in the long term, according to a recent Accenture report. While it will likely take time for providers to begin building their own digital environments in the metaverse, healthcare leaders said they believe metaverse technologies will have a positive impact on healthcare.

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Trending Sources

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AstraZeneca agrees $1.3bn deal to buy oncology player TeneoTwo

pharmaphorum

AstraZeneca has signed a deal to buy US biotech TeneoTwo in a deal worth up to $1.27 billion that will boost its position therapies for haematological cancers. The big pharma is paying $100 million upfront for the company, and offering up to $805 million in milestone payments if TeneoTwo’s drug candidates meet development objectives, plus up to $360 million if they hit sales targets.

Pharma 124
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CureVac sues BioNTech, claiming Covid-19 vaccine infringes key mRNA patents

MedCity News

Messenger RNA vaccine biotech CureVac is suing BioNTech, alleging that its rival’s Covid-19 vaccine infringes on intellectual property built on more than two decades of research. BioNTech responded that its work is original and the company will defend against the infringement allegations.

Biopharma 112
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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Self-Powered Implant Tracks Spinal Fusion Healing

Medgadget

Engineers at the University of Pittsburgh created a self-powered implant that can track spinal healing while also providing mechanical support. The device can be 3D printed so that it fits a given patient perfectly and the mechanical properties can also be easily tuned to customize for each situation. The spinal fusion cage contains a triboelectric nanogenerator that creates electricity when it is pressurized by the spine.

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Pfizer to reach carbon net-zero by 2040

European Pharmaceutical Review

After more than 20 years of environmental action, Pfizer has committed to further reduce its greenhouse gas (GHG) emissions and aims to achieve the voluntary Net-Zero Standard by 2040 – a full 10 years ahead of the standard’s proposed timeline. To achieve these goals, Pfizer aims to decrease its GHG emissions by 95 percent and its value chain emissions by 90 percent from 2019 levels by 2040.

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Scott Burrows, Insurance and Financial Speaker

Scott Burrows

Are You Prepared to Reinvent Yourself? As an insurance and financial speaker with strong ties to the industry, I have not seen such interesting—and positive—developments in years. For example, according to Statista the sales of electric vehicles are on the verge of explosion.

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How Boston Medical Center’s health equity accelerator is fast-tracking clinical improvements

MedCity News

Boston Medical Center launched a program dedicated to speeding up the timeline between discovering health inequities and implementing action plans to address them. The hospital has already made changes to its clinical guidelines based on the program’s research on preeclampsia complications among Black maternity patients.

Medical 104
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Ensuring successful digital outreach and retention in atopic dermatitis trials

pharmaphorum

Trial organisers face intense competition to find and recruit eligible patients for atopic dermatitis studies. With more than 500 dermatology clinical trials currently underway, it is often heard that there is a ‘’competition for participants’’. Yet evidence from research studies and a survey with 4,000+ atopic dermatitis patients conducted by Clariness shows that this ‘race to recruit’ is actually not the primary reason for the growing discontinuation rate of atopic dermatitis trials.

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Phase III trial shows lanadelumab reduces HAE attacks in children

European Pharmaceutical Review

Hereditary angioedema (HAE) is a genetic disorder, estimated to affect 1 in 50,000 people. It can lead to painful attacks of oedema (swelling) in various parts of the body, including the abdomen, face, feet, genitals, hands and throat. The main objective of the Phase III SPRING study ( NCT04070326 ) was to evaluate the safety and pharmacokinetics of Takhzyro ® (lanadelumab) – a fully human monoclonal antibody that specifically binds and decreases plasma kallikrein – in HAE patients aged two t

Safety 93
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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The post-Covid New Normal: a golden opportunity for the NHS?

pharmaphorum

I recently had the pleasure of attending the PING Conference 2022 , which had the tagline of ‘The Golden Age for Life Sciences Innovation’. In part, this was due to it being held at The Old Palace at Hatfield House, a location steeped in history and formerly the residence of Queen Elizabeth I, with whom ‘a golden age’ is often associated. However, it also reflected the optimistic tone of the event, organised by VWV , which aimed to present some rays of light for the future as we (hopefully) emer

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Optimising Bacillus spores for sporicidal efficacy assessments

European Pharmaceutical Review

Bacterial spores are a significant concern for aseptic pharmaceutical manufacturers due to their ubiquitous nature and intrinsic resistance to environmental stressors such as heat, as well as chemical and radiation inactivating strategies. As much as 10 percent of microbes in a pharmaceutical cleanroom are spore-forming bacteria, with strains such as Bacillus species, able to cause human disease.

Media 89
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Astellas teams up with UK biotech Mogrify on hearing loss project

pharmaphorum

Cell therapy specialist Mogrify has struck a deal with Japanese drugmaker Astellas to look at ways to deploy regenerative medicine to treat hearing loss caused by factors such as chronic exposure to loud noises. The two partners will take an in vivo approach to the problem of so-called sensorineural hearing loss (SNHL) looking at ways to replace sound-detecting hair cells in the inner ear (cochlea) that become damaged in this type of deafness.

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Sanofi launches Impact® brand of medicines for low-income countries

European Pharmaceutical Review

The Impact ® brand includes 30 Sanofi medicines and covers a wide range of therapeutic areas, including diabetes, cardiovascular disease, tuberculosis, malaria and cancer. Medicines include insulin, glibenclamide and oxaliplatin, the company said. Sanofi has also established an Impact fund to support startup companies and other innovators that can deliver scalable solutions for sustainable healthcare in underserved regions. .

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Dave Ross of Seqirus talks 'milestone' influenza vax vote

PharmaVoice

In a unanimous decision, a CDC committee calls for a preferential flu vaccine recommendation for people aged 65 and older for the first time.

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Novel oral chemotherapeutic holds potential for stomach cancer patients

European Pharmaceutical Review

Stomach cancer, also known as gastric cancer, is the fifth most common type of cancer worldwide – and the third most common cause of death from cancer. 1 Approximately half of all cases occur in eastern Asia, but thanks to more advanced screening programmes in countries like Japan, survival rates in these regions are improving compared with western countries.

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Microfluidic Chip Models Inflammatory Intestinal Disease

Medgadget

Researchers at Harvard’s Wyss Institute have modeled Environmental Enteric Dysfunction (EED), a childhood inflammatory intestinal disease, on a microfluidic chip and gained new insights into the genetic changes underlying the condition. This is the first in vitro model of the disease, and highlights the power of organ on a chip systems to provide insights into complex disease states.

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Talent Acquisition Strategies for Medical Sales Recruiters

MedReps

If you have medical sales opening to fill, you should know the most effective talent acquisition strategies. Maybe at one time, the process was as simple as placing an ad and sorting through a handful of candidates. However, today, the best salespeople have options, and hiring managers must employ different strategies to find the best ones. For our discussion, we’ve assumed that your role is to hire and manage sales representatives.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Pharma companies take a fresh approach to inclusion in new DTC ads

PharmaVoice

AstraZeneca and Amgen are emphasizing diversity and authenticity in campaigns for lupus and severe asthma therapies.

Pharma 98
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What Gets Measured Gets Done: The Proven Sales Plan from Jasper Engines

Map My Customers

Managing a large sales team can often lead to challenges within an organization. Having a defined sales process can lead the team through those challenges and bring continued success. Much like many businesses in the early part of 2020, Jasper Engines was faced with the unknown of what the year would bring, and how they would adjust their organization to the changes going on around us in our everyday lives.

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A Harvard Dean’s Blueprint for Fortune 500 C-Suites to Magnify Their Growth Opportunities

Pharmaceutical Commerce

Dr. Frank Doyle, Dean of the Paulson School of Engineering and Applied Sciences at Harvard University, outlines his recommendations for Fortune 500 c-suites as they strive to attract, develop, and retain the best talent for their upcoming 2023 strategic plans.

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AlzeCure’s Alzheimer’s candidate shows promise

PharmaTimes

Treatment abstract focuses on results from a multiple ascending dose study in healthy volunteers

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

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How to Market to Doctors, Physicians, and Other Health Care Professionals

Healthcare Success

Marketing to doctors, physicians, surgeons, and other health care professionals can be extremely challenging, complicated, and expensive. What’s more, most doctors work in a hospital or multilocation medical practice, making it even more challenging to identify key decision-makers. Not only are doctors and decision-makers difficult to reach—and even more difficult to persuade—you have to contend with a ton of competition.

Doctors 61
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Sanofi unveils global health brand for medicines supply

Pharmaceutical Technology

Sanofi has unveiled the global health brand, Impact, to make available standard of care treatments for non-profit supply to at-risk populations in low-income countries. Through the Impact brand, which comprises insulin, glibenclamide and oxaliplatin among others, the company will supply its 30 medicines in 40 lower-income countries in the world. The therapies cover a broad range of treatment areas, including diabetes, cardiovascular disease, tuberculosis, malaria and cancer and are regarded esse

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Bloom’s smart CRP test gets green light

PharmaTimes

C-Reactive protein test gets go-ahead for professional use across Europe

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AstraZeneca signs agreement to acquire TeneoTwo

Pharmaceutical Technology

AstraZeneca has signed an agreement for the acquisition of all outstanding equity of TeneoTwo as well as its CD19/CD3 T-cell engager, TNB-486, in a deal worth up to $1.27bn to bolster the haematological cancer pipeline. As per the deal, AstraZeneca will make an upfront payment of $100m on the closing of the transaction. Furthermore, equity holders of TeneoTwo are entitled to get up to $805m in research and development (R&D)-based milestone payments as well as up to $360m as commercial-relate

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Marketing to Doctors and Physicians

Healthcare Success

How to create marketing and lead generation systems that get results. By Stewart Gandolf, MBA. (Editor’s Note: I wrote the first version of this blog post back in 2006 when we launched Healthcare Success. While I intentionally wrote it with a quick, playful tone, more than sixteen years later, it remains one of our most popular posts. I recently updated it here for your reading pleasure!).

Doctors 57
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Lab Digitalization: From Source to Scientist

PharmaTech

Integrating digital technologies into lab environments can ease workflow and enhance data capture for researchers.

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What are the Benefits of Having an EHR?

Referral MD

Photo by Wesley Tingey on Unsplash With the rise of digital transformation, new technologies are revolutionizing the healthcare industry. Practitioners all over the world have now switched to computerized records. Compared to other industries, this change in the medical field took a considerable amount of time. After implementing the 2009 Health Information Technology for Economic and Clinical Health (HITECH) Act, US clinics were provided sufficient funds to adapt to newer electronic practices

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From Hardware To Medical Sales Rep To Nurse Tech Guru With Duston Harper

Evolve Your Success

Put yourself out there. That’s the key to achieving your goals and succeeding in your preferred industry. You can always work on a routine to help you develop the right mindset for continuous growth. Tune into this episode as Samuel Gbadebo as he sits down for a conversation with Nurse Tech Guru Duston Harper about making nurses’ lives easier and safer by helping hospital administration solve problems.

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The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.