Tue.May 23, 2023

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Amid high-profile injectable launch, Novo Nordisk scores with its pill version of obesity drug Wegovy

Fierce Pharma

Amid high-profile injectable launch, Novo Nordisk scores with its pill version of obesity drug Wegovy kdunleavy Tue, 05/23/2023 - 10:34

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Webinar: HCP customer experience in pharma

Dominic Tyer

On Wednesday 24 May I’ll be discussing recent DT Consulting research on how to best engage HCPs over digital and non-digital channels and what content experiences best connect with them

Pharma 130
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Trending Sources

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The clock's ticking on Stelara: Amgen, J&J ink patent settlement

Fierce Pharma

The clock's ticking on Stelara: Amgen, J&J ink patent settlement esagonowsky Tue, 05/23/2023 - 17:08

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Health Tech Startups Show Stakeholders How Digital Solutions Can Offer ROI

MedCity News

A panel during the MedCity News INVEST conference discussed what digital health technologies need to do to demonstrate return on investment for payers, providers, and other stakeholders.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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ASCO: Bristol Myers' $4B plan for Reblozyl takes shape in blood cancer anemia—with one caveat

Fierce Pharma

ASCO: Bristol Myers' $4B plan for Reblozyl takes shape in blood cancer anemia—with one caveat aliu Tue, 05/23/2023 - 17:18

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European biotechs choosing Switzerland as base, research shows

European Pharmaceutical Review

New research by IQVIA and recently published in the 2023 Swiss Biotech Report shows that 20 percent of European biotech companies are now headquartered in Switzerland. Sixty three out of a total of 265 companies settling in Switzerland were biotechs. This makes it the second most important sector after ICT, the research found. 2022 statistics by the Swiss federal government confirm that the trend to base here is continuing.

Biopharma 112

More Trending

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MedCity INVEST Ask the Investor Spotlight: Yaniv Sneor of Mid Atlantic Bio Angels

MedCity News

Yaniv Sneor, the co-founder of Mid Atlantic Bio Angels and part of the Ask the Investor sessions at MedCity INVEST this week, explained what his firm looks for in life science startups.

Biopharma 106
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Avrobio to sell cystinosis gene therapy to Novartis for $87.5m

Pharmaceutical Technology

Avrobio has announced a deal to sell its investigational haematopoietic stem cell (HSC) gene therapy programme , designed to treat cystinosis, to Novartis in an all-cash deal valued at $87.5m. Novartis will receive an exclusive licence for intellectual property related to the gene therapy platform of Avrobio for use in cystinosis and for other assets.

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Small, Rural Communities Have Become Abortion Access Battlegrounds

MedCity News

The quest to enact local bans has become particularly acute in small towns, like West Wendover, Nevada, and Hobbs, New Mexico, which are situated by borders between states that have restricted abortion and states where laws preserve access.

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US FDA approves Blueprint Medicines’ indolent systemic mastocytosis therapy

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has granted approval for Blueprint Medicines’ Ayvakit (avapritinib) as the first and only treatment for indolent systemic mastocytosis (ISM) in adult patients. The precision therapy has been designed for potently and selectively inhibiting KIT D816V, which is the main underlying driver of the disease. It received FDA approval to treat ISM, advanced SM, including SM with an associated haematological neoplasm (SM-AHN) and mast cell leukemia (MCL), and aggr

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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How Can the Healthcare Industry Make It Easier for Patients To Make Healthier Food Choices?

MedCity News

It shouldn’t be so hard for Americans to access healthy foods, said Dr. Elizabeth Klodas, founder of healthy food company Step One Foods, during a Tuesday panel at the MedCity INVEST conference in Chicago. There should be incentives for food companies and better nutrition education for Americans.

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The Power of Healthcare Data Analytics

LEVO Health

In the dynamic world of healthcare marketing, understanding your audience and optimizing your strategies are key to staying ahead of the competition. Practices can use healthcare data analytics to gain insights that can transform their marketing efforts in the digital age. Data analytics is the process of collecting and analyzing data to make informed decisions.

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How CommonSpirit’s CIO Ensures That New Technology Investments Are Worth It

MedCity News

During MedCity News’ INVEST conference, CommonSpirit Health CIO Daniel Barchi laid out two critical actions that hospitals can take to help ensure their new technology investments will be worth their time and money. The first is to prioritize scalability, and the second is to involve frontline clinical staff early on in the process.

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Croda Pharma and BSI partner for vaccine adjuvant QS-21 production

Pharmaceutical Technology

Croda Pharma has entered a strategic collaboration deal with Botanical Solution Inc (BSI) to expedite the production of sustainable pharmaceutical-grade vaccine adjuvant QS-21. QS-21 is a potent component of adjuvant systems used in vaccines for diseases such as RSV, malaria and shingles, as well as in new vaccines and immunotherapy treatments such as cancer.

Pharma 96
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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Cell Culture Chamber Mimics Mechanical States of Disease

Medgadget

Researchers at the University of Göttingen in Germany have developed a cell culture chamber that lets them culture tissue samples, mimic the mechanical conditions that tissues experience in various disease states, and closely monitor tissue reactions. The technology could be particularly useful for pre-clinical drug testing, allowing researchers to test the effects of various drug candidates on tissues without the need to use experimental animals.

Ethics 95
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The power of genetics — how research into gene sequencing could revolutionize biopharma

PharmaVoice

Ancient DNA from a deer tooth. A new way to connect genes with disease. Biological super-computing. These genetic advances could play a part in our biopharma future.

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Machine learning can predict outcomes for inkjet printed pharmaceuticals

European Pharmaceutical Review

Using inkjet printing, optimised machine learning (ML) models predicted the printability of drug formulations with an accuracy of 97.22 percent, a paper published in International Journal of Pharmaceutics: X has shown. Inkjet printing makes formulation and printing parameter optimisation time-consuming. This is especially true for additive manufacturing and the production of unique dosage forms and personalised medicines.

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Automated Computer Assistant for Kidney Transplant Rejection Diagnostics: Interview with Study Authors

Medgadget

A recent study in Nature Medicine , entitled “ An automated histological classification system for precision diagnostics of kidney allografts ,” has showcased the efforts of a group of researchers who have developed an automated system that can diagnose kidney transplant rejection. A variety of disparate factors can affect the chances that a transplant will be rejected.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Iraqi Publisher Wins IPA’s Prix Voltaire, Slain Ukrainian Author Honored

Copyright Clearance Center

The post Iraqi Publisher Wins IPA’s Prix Voltaire, Slain Ukrainian Author Honored appeared first on Copyright Clearance Center.

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TriNet Pharma Highlights the Rise of the Medical Science Liaison and Honors Legacy of Its Founder [Sponsored]

MedCity News

As pharmaceutical reps are used less and less, the role of the MSL has become more prominent as a conduit between life sciences companies and external stakeholders for drug development.

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6 Cost-Effective Tools For Your Medical Sales Job Hunt

MedReps

Preparing to apply for medical sales jobs requires more than just an updated resume and a detailed cover letter. You also need a number of different tools in order to successfully interview for jobs and stay organized so you don’t miss out on submitting an assessment on time. Thankfully, many of these tools are inexpensive or even free, making them even better for assisting you with your job hunt.

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From Inside-Out to Outside-In: Rethinking Patient Engagement

MedCity News

We live in a world in which the patient is empowered like never before.

Patients 123
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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Soft Robotic Electrode Enables Minimally Invasive Placement

Medgadget

Researchers at Ecole Polytechnique Fédérale de Lausanne (EPFL) in Switzerland have developed a soft robotic electrode, that can be advanced through a small hole in the skull and then opened into a series of spiral arms, to provide electrocorticography measurements from a relatively large area of the brain surface. The technology could prove very useful for brain surgeons who wish to map regions of the brain that may be triggering epileptic seizures and then target these lesions surgically.

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Positive data for AnaMar’s fibrosis therapy

PharmaTimes

Receptor antagonist AM1476 developed as an anti-fibrotic treatment for lung and skin disorders

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ReNAgade Therapeutics enters RNA therapy arena with $300m

Pharmaceutical Technology

ReNAgade Therapeutics has burst onto the RNA technology scene by announcing a $300m financing round. As per the company, the round, led by MPM BioImpact and F2 Ventures, is the largest Series A funding round of 2023. Founded by MPM BioImpact, ReNAgade’s portfolio includes novel lipid nanoparticles (LNPs). With its delivery system, Cambridge, Massachusetts-based biotech says it aims to “address major limitations in RNA therapeutics by enabling the delivery of RNA medicines to previously inaccessi

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Scarlet Therapeutics gains funding for blood cell platform

PharmaTimes

Vital financing will allow the company to build a pipeline of novel therapies targeting serious conditions

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Scott Burrows, Texas Motivational Speaker

Scott Burrows

How Can We Not Feel Pride in Texas? “Optimism isn’t just a state of mind, it’s a practice. But seizing an opportunity to improve things can rarely be done alone. Texans work together every day to help their neighbors, respond to disaster, and build brighter futures.

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Myeloid Therapeutics Gets $73 Million to Advance mRNA-based Pipeline

PharmaTech

With $73 million in financing from investment firms, Myeloid Therapeutics plans to accelerate its lead clinical candidate into Phase I/II development for treating solid tumors.

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Virtual Reality Training For Medical Device Sales Reps With David Howe

Evolve Your Success

Virtual reality is not just a game-changer for medical sales, but a life-changer for all of us. It’s a tool that allows us to practice, learn, and grow in ways we never thought possible. And the potential for its impact on our world is limitless. In this episode, Samuel Adeyinka interviews David Howe to explore the world of virtual reality training for medical device sales reps.

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Who’s innovating where? Environmental sustainability related patent filings activity decreased by 23% in the pharmaceutical industry in Q1 2023

Pharmaceutical Technology

The global pharmaceutical industry experienced a 23% decline in the number of environmental sustainability-related patent applications in Q1 2023 compared with the previous quarter. The total number of environmental sustainability-related grants dropped by 24% in Q1 2023, according to GlobalData’s Patent Analytics. With an increasing focus on ESG, Pharmaceutical companies are under pressure to incorporate sustainability with suppliers playing a crucial role in the process.

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.