Fri.Oct 06, 2023

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'Extremely concerning' chemo shortage persists despite FDA's efforts, national cancer group reports

Fierce Pharma

While the White House recently touted the FDA’s efforts to mitigate the ongoin | The National Comprehensive Cancer Network found that 72% of centers are still experiencing a carboplatin shortage, while 59% remain low on cisplatin. The survey follows a June report which found that nearly all centers had short supply of the chemotherapies.

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How Are Digital Health Investors Shifting Their Focus In 2023?

MedCity News

The digital health sector’s quarterly investment trends seem to be stabilizing in 2023, according to a new report from Rock Health. The report noted investors are shifting their focus away from pandemic-era categories like telehealth and pharmaceutical R&D catalysts — instead, they’re interested in startups creating products for disease treatment, the improvement of nonclinical workflows and the enablement of value-based care.

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After short FTC fight, Amgen wraps up $27.8B Horizon buyout

Fierce Pharma

Amgen has completed its $27.8 billion acquisition of Horizon Therapeutics after fending off a legal challenge by the U.S. antitrust watchdog. | Amgen has completed its $27.8 billion acquisition of Horizon Therapeutics after fending off a legal challenge by the U.S. antitrust watchdog.

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Supporting Aging Populations and Their Caregivers

MedCity News

The world is slowly aging, and by 2060, around 94.7 million older adults will be in the U.S. Without the proper care tactics in place, healthcare providers risk losing people at an earlier age and burning out family caregivers.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Novo Nordisk's weight-loss drugs pose small risk of severe stomach complications: study

Fierce Pharma

People who use Novo Nordisk’s popular weight-loss drugs are taking on a small risk of developing severe stomach problems, according to research conducted by the University of British Columbia and < | People who use Novo Nordisk’s popular weight-loss drugs are taking on a small risk of developing severe stomach problems, according to research conducted by the University of British Columbia.

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Hospitals Turn to Backup Power When Extreme Weather Hits Propane Generators Offer Clean Solution

MedCity News

Propane can provide reassurance during this time of strain on the electric grid. It can keep hospitals and other critical facilities powered so that patients receive the care they need, and allow emergency responders to do their jobs effectively.

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Liquid Biopsy Startup Precede Sets Out to Make Precision Medicine More Precise

MedCity News

Precede Biosciences’ liquid biopsy platform yields insight into the genes and pathways in diseased tissue. Based on Dana-Farber Cancer Institute research, the startup aims to support biopharma drug R&D as it also develops the technology for clinical care applications.

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Moderna reveals optimistic data for influenza-COVID-19 vaccine

European Pharmaceutical Review

Positive interim results from Moderna’s Phase I/II trial of mRNA-1083 , an investigational vaccine designed to immunise against both influenza and COVID-19, have been released. There are several benefits of the combination vaccine as a preventative measure against these respiratory conditions, according to the pharmaceutical company. For example: higher patient compliance, easier administration and greater convenience.

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Ounce Raises $5.2M for Housing and Care Coordination Platform

MedCity News

Ounce’s $5.2 million in seed funding was co-led by Meridian Street Capital and Flare Capital and included participation from Chelsea Clinton’s Metrodora Ventures, Wilshire Lane Capital, Hilton CEO Chris Nassetta and Unite Us Co-founder Taylor Justice.

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LogiPharma USA 2023: Tracy Nasarenko Discusses the GS1 US Addendum Guidance and XML Examples for GS1 US DSCSA Implementation Guideline R1.3

Pharmaceutical Commerce

Sr. Director of Community Engagement for Pharmaceuticals at GS1 US explains what the implementation guidelines are meant to accomplish.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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India joins mission to harmonise pharmacopoeial standards

European Pharmaceutical Review

The Indian Pharmacopoeia Commission (IPC) is now a member the Pharmacopoeial Discussion Group (PDG). As the Indian pharmaceutical industry is “a major manufacturer of the world’s medicines,” Jaap Venema, PhD, Executive Vice President and Chief Science Officer for USP declared, inclusion of the IPC in the discussion group is a “milestone” in expanding recognition of harmonised pharmacopoeial standards, Cathie Vielle, Secretary to the European Pharmacopoeia Commission added.

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LogiPharma USA 2023: Impactful Roundtable Discussions

Pharmaceutical Commerce

Conference hosts roundtable chats, with topics ranging from data-driven decision making to cold chain logistics.

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Ocular launches ocular implant trial to combat macular degeneration

Pharmaceutical Technology

Ocular Therapeutix has confirmed the launch of a trial of an intravitreal eye implant intended to combat macular degeneration.

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AstraZeneca reveals new research to improve drug discovery

PharmaTimes

The study used data from 50,000 people in the UK Biobank - News - PharmaTimes

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Q&A With Daniel Lofaso, CEO of Digital Elevator

PharmExec

Lofaso discusses strategies that biotech companies can take once its time to make the big push.

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UK launches its first national PET imaging platform for drug discovery

PharmaTimes

NPIP will transform medical research and provide better outcomes for patients - News - PharmaTimes

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Azzur Group Appoints James Kalinovich as Chief Financial Officer

PharmExec

Kalinovich previously worked at Wabtec as a corporate vice president.

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UK launches total-body PET drive to support drug discovery

pharmaphorum

UK launches total-body PET drive to support drug discovery Phil.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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UK Poised to Lead Global Delivery of Next-Gen mRNA Medicines

PharmaTech

The BioIndustry Association reports that with a strong foundation in research and development in mRNA the United Kingdom will be a major player in this rapidly growing industry.

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Beyond the List: Innovative Strategies for Engaging Canadian Pharmacists in B2B Ventures

Scott’s Directories

The Canadian healthcare sector, particularly the pharmacy industry, is massive and growing. With thousands of medical professionals, including general practitioners and specialists, the industry offers a rich ground for B2B ventures. Therefore, sales and marketing teams, data research groups, and pharmaceutical companies seeking to engage with this sector need more than just a list of pharmacies in Canada ; they require strategic approaches to connect and communicate with these professionals eff

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Programmatic Advertising: A Pharma Marketer’s Guide to Precision

Pharma Marketing Network

Programmatic advertising is a modern form of digital media buying that has become increasingly popular with pharma marketers. It allows for precise targeting of potential customers, and is a great way to reach the right people with the right message. This article will provide an overview of programmatic advertising, its advantages for pharma marketers, strategies for precision, and challenges to consider.

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CTMC Partners with ScaleReady for Combatting Manufacturing Barriers

PharmaTech

The agreement will enable CTMC to strategically scale the recently completed good manufacturing practice facility to drive high-throughput manufacturing utilizing the automated, closed system capabilities of the Fresenius Kabi Lovo and Cue cell processing systems.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Arkansas Children’s Looks Beyond the Diagnosis in Launch of Art Gallery Celebrating Children with Rare Diseases

PM360

Children with rare diseases know a lot about some pretty grown-up topics. Many can tell you how doctors treat their life-altering symptoms while in pre-school. Others can recall lengthy therapy names before their first spelling test. Some can share statistics that prove just how unique they truly are while their peers are still learning to count. Arkansas Children’s , a leader in primary and specialty care, is teaming up with nonprofit Beyond the Diagnosis to make sure the beauty of chil

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What is a Sales Compensation Budget Risk Analysis and Why is it Important?

The Marketing Advantage

October 6, 2023 One of the most challenging aspects of utilizing a sales compensation plan that does not have a fixed budget is that, too often, the plan ends up paying more or less than expected. While less effective sales compensation plans such as forced rank provide the ability to know the total that will be paid out in advance, more effective and equitable sales compensation plans such as goal and commission do not, which can result in such designs not being utilized or payouts under such d

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Cadence Announces the Acquisition of ARC Group Worldwide’s Florida Location

Legacy MEDSearch

Cadence, Inc., a leading provider of design, development, and contract manufacturing services to the medical device, drug delivery, and diagnostics markets, announced today that it has acquired the Florida location of ARC Group Worldwide ( arcw.com ), a precision manufacturer specializing in Metal Injection Molding (MIM) and cleanroom plastic injection molding.

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Topical Ketamine: A Promising New Avenue for PTSD Treatment

Pharmacy Times

Ketamine topical cream may alleviate symptoms of PTSD without causing the adverse effects and abuse potential often associated with other forms of ketamine administration.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Orchard will help Kyowa Kirin grow in gene therapy

pharmaphorum

Orchard will help Kyowa Kirin grow in gene therapy Phil.

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Biologics emerge as dominating molecule type in solid tumour indication

Pharmaceutical Technology

Biologics are poised to overtake innovative small molecules in terms of sales revenue by 2027, with forecast sales of $120bn.

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Boehringer moves obesity therapy into phase 3

pharmaphorum

Boehringer moves obesity therapy into phase 3 Phil.

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FDA panel says Amgen’s Phase III lung cancer KRAS drug data is unreliable

Pharmaceutical Technology

The panel identified several issues with the trial including study organisation and loss of follow-up data from patients who withdrew consent.

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.