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Research predicts 2029 small molecule oncology market leaders

European Pharmaceutical Review

Strong demand for small molecules as treatment for non-small cell lung cancer (NSCLC) in the eight major markets means that the small molecule treatment market for the disease is expected to reach over $15 billion by 2029. billion and a market share of 17 percent by 2029, GlobalData predicted. percent by 2029.

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What sets the Drugs to Watch in 2024 apart

Clarivate

These new treatments hold tremendous promise to advance patient care and fuel the next generation of medical breakthroughs. Clarivate data indicates a 90% probability that datopotamab deruxtecan will win marketing authorization in the United States, and projects 2029 sales of $2.7 billion in 2029 for CASGEVY alone.

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EGFR inhibitor could provide major advance in lung cancer

European Pharmaceutical Review

Small molecule treatment TAGRISSO ® (osimertinib) demonstrated a “statistically significant and highly clinically meaningful improvement” in progression-free survival (PFS) for Stage III lung cancer patients, AstraZeneca has confirmed. This was established from positive high-level results seen in the LAURA Phase III trial.

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Novo Nordisk blockbuster Ozempic boasts 23% sales surge in 2023

Pharmaceutical Technology

In 2022, US sales of Ozempic contributed to 65% of global sales; this is expected to continue, with the US market forecast to continue capturing the majority of sales, generating $71bn between 2023–2029. It is forecast that Ozempic will sustain its sales growth over the next five years, with an expected annual sales figure of $17bn in 2029.

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US legislation to benefit small molecule drug innovation

European Pharmaceutical Review

As a “vital class of treatments” for patients worldwide, King considered that the new legislation would “fix a section of the US Inflation Reduction Act (IRA) and make certain that we are not disincentivising the development of small molecule drugs that are often more accessible for patients”.

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Novo Nordisk plans multi-billion Denmark manufacturing expansion

European Pharmaceutical Review

The construction projects will be finalised from the end of 2025 through to 2029. This important investment will ensure the continuous development of our late-phase pipeline into deliveries of important medicines for treatments to patients worldwide”, Wulff declared in the original annoucement.

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Could obicetrapib facilitate sufficient LDL-cholesterol levels?

European Pharmaceutical Review

Clinical benefits seen in the obicetrapib Phase II ROSE2 trial In the Phase II ROSE2 trial, patients received a combination therapy of 10mg of obicetrapib or placebo for 12 weeks. LDL-C levels were observed to lower in 88 percent of patients to less than 55mg/dL. At 12 weeks, LDL-C was reduced by 43.5 percent and 40.2