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Research predicts 2029 small molecule oncology market leaders

European Pharmaceutical Review

Strong demand for small molecules as treatment for non-small cell lung cancer (NSCLC) in the eight major markets means that the small molecule treatment market for the disease is expected to reach over $15 billion by 2029. Roche is expected to secure second position in the market, due to projected sales of over $2.5 percent by 2029.

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Novo Nordisk blockbuster Ozempic boasts 23% sales surge in 2023

Pharmaceutical Technology

Novo Nordisk’s leading drug Ozempic (semaglutide) is forecast to demonstrate a sales growth of 23% in 2023. Ozempic’s forecast 2023 sales of $12.5bn consolidate its position as the dominant market leader, with projected sales in 2023 54% greater than closest competitor Trulicity (dulaglutide) by Eli Lilly, which anticipates sales of $8bn.

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What sets the Drugs to Watch in 2024 apart

Clarivate

These new treatments hold tremendous promise to advance patient care and fuel the next generation of medical breakthroughs. Clarivate data indicates a 90% probability that datopotamab deruxtecan will win marketing authorization in the United States, and projects 2029 sales of $2.7 billion in 2029 for CASGEVY alone.

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NICE recommends AbbVie’s/J&J’s Imbruvica for combo use in untreated CLL

Pharmaceutical Technology

There, the data shows that patients on this regimen live longer lives along with having a greater period of time before disease progression, than with other treatments. CLL is regarded as the most common type of leukaemia in England where 3,157 patients were diagnosed with the disease in 2017, based on the institute’s announcement.

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Could obicetrapib facilitate sufficient LDL-cholesterol levels?

European Pharmaceutical Review

Clinical benefits seen in the obicetrapib Phase II ROSE2 trial In the Phase II ROSE2 trial, patients received a combination therapy of 10mg of obicetrapib or placebo for 12 weeks. LDL-C levels were observed to lower in 88 percent of patients to less than 55mg/dL. At 12 weeks, LDL-C was reduced by 43.5 percent and 40.2

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Regeneron, CytomX announce bispecific therapeutics for cancer collab

pharmaphorum

Dr John Lin, senior vice president of immune-oncology and head of bispecifics at Regeneron , said: “The collaboration will enable Regeneron and CytomX to combine our collective oncology expertise with two premier platforms […] to develop novel immunotherapies and research their potential to transform patient lives.”.

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Seeking Ofev successor, Boehringer takes PDE4B drug into phase 3

pharmaphorum

The first patient has already been enrolled into its FIBRONEER phase 3 programme for BI 1015550, which already has a breakthrough designation from the FDA after a positive phase 2 trial showed improved lung function in patients with IPF over a 12-week period. There are more than 200 lung disorders that can lead to pulmonary fibrosis.