Pharmaceutical Technology

MAY 19, 2023

DMTs for MS have a high price tag, particularly in the US. According to GlobalData’s recent Multiple Sclerosis: Seven-Market Drug Forecast and Market Analysis to 2030 – Update report, which identified 19 DMTs marketed for MS in the US, the average annual cost of therapy increased by 9% between 2020 and 2022.

Prospecting 98

Prospecting Marketing Patients Leads 98

Pharmaceutical Technology

JUNE 29, 2022

This year has already been eventful when it comes to the development of therapies for rare diseases. Most, if not all, of these therapies used the FDA’s Orphan Drug Designation to aid their development plans. So far this year, 176 drugs have already received this designation.

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Food and Drug Administration FDA Marketing Pharmaceutical 98

Pharmaceutical Technology

DECEMBER 15, 2022

In an expanded version of the sales forecast from GlobalData’s June 2022 publication, Cardiomyopathies: Global Drug Forecast and Market Analysis , the global cardiomyopathies market is expected to grow from $3.07bn last year to $9.63bn in 2031. of sales in 2021 and 2031 respectively. of global cardiomyopathies sales in 2021 and 31.2%

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Pharmaceutical Technology

JULY 14, 2022

The commercial investment required to research and develop an innovative drug, prove its safety and efficacy, and bring it to market is staggering. Most famously, the US passed its Orphan Drug Act in 1983, providing innovators with financial motivation to develop orphan drugs and meet the needs of these forgotten patients.

Medicine 59

Medicine Marketing Specialization Pharma 59

European Pharmaceutical Review

AUGUST 24, 2022

ANTIBODY-DRUG conjugates (ADCs) are therapeutic molecules designed as highly targeted medicines with the promise of changing the way we treat cancer and other diseases. In total, there are 14 approved ADCs on the global market, all for oncology indications, and over 140 ADCs currently in clinical development.

Engineering 81

Engineering Side effects Marketing Patients 81

pharmaphorum

AUGUST 25, 2022

Johnson & Johnson has its first worldwide regulatory approval – in the EU – for Tecvayli, one of two much-anticipated bispecific antibodies the drugmaker has developed for patients with multiple myeloma. Tecvayli previously scored a priority medicines (PRiME) designation from the EMA and a breakthrough-therapy tag from the FDA.

FDA 92

FDA Marketing Safety Patients 92

pharmaphorum

AUGUST 21, 2022

NMDA antagonist dextromethorphan is an ingredient found in cough syrups, while bupropion is an established antidepressant that was originally developed by GSK and sold as Wellbutrin. However, it has a broader label as unlike J&J’s drug it is indicated for use in previously-untreated MDD. Photo by Sydney Sims on Unsplash.

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FDA Marketing Pharma Sales 87

European Pharmaceutical Review

MARCH 1, 2023

In a recent study, Massachusetts Institute of Technology (MIT) researchers developed a new purification method to cut the costs of manufacturing protein drugs. Producing biologics by isolating proteins Biologics like antibodies and other protein-based drugs are produced by living cells such as yeast in large bioreactors.

Manufacturing 92

Manufacturing Engineering Leads Pharmaceutical 92

pharmaphorum

JANUARY 9, 2023

” Zolgensma is one of the most expensive therapies available, with a price tag of around $2.1 ” NHS England said the temporary change in eligibility – which ties in with NICE guidance – has been implemented as there are two other disease-modifying drugs available on the NHS for the treatment of SMA.

Side effects 113

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PM360

OCTOBER 13, 2023

Another capability made possible by fine-tuning is the enhancement of content tagging. Content tagging has always been a labor-intensive task. Auto-tagging ensures that the right content efficiently reaches the right customers. Fine-tuning models can target domains and generate prompts to tag the content into relevant topics.

Marketing 64

Marketing Specialization Healthcare Healthcare 64

pharmaphorum

DECEMBER 23, 2022

There’s been huge progress in treatments for blood cancer in recent years – but drawbacks of expensive CAR-T cell and injected antibody therapies have led drug developers to look at novel oral therapies as patient-friendly alternatives. Results suggest durable epigenetic re-wiring and provide rationale for intermittent clinical dosing.

Side effects 52

Side effects Patients Medical Medicine 52

PM360

APRIL 22, 2024

From defining the target product profile to shaping clinical endpoints and devising asset strategies to crafting scientific narratives, the value of Medical Affairs permeates every aspect of product development. An honest understanding of Medical Affairs situations and needs will be essential to ensure data-driven decision-making.

Medical 52

Medical Healthcare Healthcare Education 52

Pharmaceutical Technology

FEBRUARY 22, 2023

The legal dispute is centered around rival cholesterol-lowering drugs produced by the two companies, which were approved in the summer of 2015. Developed by Sanofi and Regeneron, Praluent was approved by the FDA in July 2015. Both drugs are monoclonal antibodies that inhibit the protein PCSK9.

Pharma 104

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pharmaphorum

JULY 25, 2022

The new drug is one of two bispecifics for multiple myeloma in the late-stage pipeline of J&J’s Janssen division stemming from its longstanding and fertile collaboration with Danish biotech Genmab, along with talquetamab which binds to CD3 and GPRC5D. In the MagnetisMM-3 trial, elranatamab was associated with an ORR of 60.6%

Medicine 52

Medicine FDA Recruitment Patients 52

pharmaphorum

NOVEMBER 27, 2022

Incidents such as the hormone replacement therapy drug shortage in early 2022 have shown the damaging impact supply chain issues can have on people who depend on these drugs. Mix ups in hand-offs are another large disruptor, especially when drugs have specific shipping requirements. Automation can be such a solution.

Pharma 100

Pharma Safety Pharmaceutical Manufacturing 100

Pharmaceutical Technology

MAY 15, 2023

Innovation S-curve for the pharmaceutical industry Peptide nano-particle conjugates is a key innovation area in the pharmaceutical industry By tagging peptides with nanoparticles, peptide nano-particle conjugates allow enhanced control over their biological behaviour, overcoming intrinsic limitations of the individual materials.

Pharmaceutical 52

Pharmaceutical Leads Biopharma Medicine 52

Pharmaceutical Technology

APRIL 5, 2023

More than a decade after the first patient was treated with a CAR-T therapy, six therapies relying on the same principles have been approved by the US Food and Drug Administration (FDA) and marketed to thousands of patients. More broadly however, several advancements are on the horizon for cell and gene therapies in 2023.

Food and Drug Administration 59

Food and Drug Administration Engineering Patients Education 59

LEVO Health

JANUARY 31, 2023

This can include optimizing the website’s content, meta tags, and images for search engines. New treatments, drugs, and technologies are constantly being developed. SEO is the practice of optimizing a website to rank higher in search engine results for relevant keywords and phrases.

Healthcare 96

Healthcare Healthcare Marketing Engineering 96

pharmaphorum

JANUARY 31, 2023

When patients do not take their medications according to the prescribed instructions, the drugs will not work as effectively as they did under the controlled conditions of a clinical trial. Given the high price tags placed on many medications, it’s easy to understand why patients often feel that they are being taken advantage of.

Patients 52

Patients Pharma Side effects Education 52

Pharmaceutical Technology

MARCH 22, 2023

The pharmaceutical industry began using radio frequency identification (RFID) tags in the early 2000s. Pfizer was the first to use the tech, adding RFID tags to track a Viagra (sildenafil) shipment circa 2006. As computing has developed in the past decade, so has the potential to store and use information in the cloud.

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Food and Drug Administration Electronics Pharma FDA 105

pharmaphorum

NOVEMBER 16, 2022

The advancements made in drug development over the last decade have seen the arrival of a number of treatments that offer one-time cures and more effective therapies for conditions in smaller patient populations. However, with a price tag of €1.58 How to navigate the new climate. At more than $2.1

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Medicine Marketing Healthcare Healthcare 123

Pharmaceutical Technology

JUNE 21, 2023

The high price tag may be hard to defend , but with lifetime treatment costs for haemophilia B reaching as high as $23m for some, the single-dose treatment could prove far more cost-effective. Already a big player in haemophilia treatments, CSL licensed exclusive global rights to Hemgenix from gene therapy developers uniQure back in 2021.

Patients 98

Patients Food and Drug Administration Engineering Sales 98

pharmaphorum

NOVEMBER 28, 2022

Substra is the software that powered the MELLODDY platform, a collaboration in which Amgen, Astellas, AstraZeneca, Bayer, Boehringer Ingelheim, GSK, Janssen, Merck, Novartis, and Servier all agreed to share drug discovery data — but not with each other directly, nor with Owkin. Open source is undoubtedly the future of AI research.”.

Training 72

Training Medical Pharma Healthcare 72

European Pharmaceutical Review

NOVEMBER 10, 2022

Complex medicines offer diverse therapeutic modalities, including RNA therapeutics and antibody-drug conjugates (ADCs). Advanced light microscopy techniques can be used to better understand complex medicines and establish new approaches for discovery and development. What constitutes a complex medicine? Figure 1 ).

Medicine 95

Medicine Distribution Engineering Electronics 95

Copyright Clearance Center

NOVEMBER 7, 2023

Researchers need easier ways to access the latest clinical evidence and identify trends within the data for a multitude of use cases across the drug development lifecycle,” said Tracey Armstrong, President and CEO, CCC. The new connector expands users’ access to this data from around the world.

Management 115

Management 115

European Pharmaceutical Review

MAY 11, 2023

In this Q&A, Dr Sitra Tauscher-Wisniewski, Vice President of Clinical Development & Analytics of Novartis Gene Therapies elaborated on the key findings and discussed the importance of collaboration in fast-tracking access to gene therapies such as Zolgensma. 1 This is assuming a $1M price tag for all gene therapies.

Food and Drug Administration 69

Food and Drug Administration Government Healthcare Healthcare 69

PM360

APRIL 7, 2023

It’s never too early in the research and development (R&D) process to identify and measure a product’s projected clinical outcomes in order to meet the needs and expectations of payers and healthcare professionals (HCPs) who are the final arbiters of a product’s commercial success. million for the new hemophilia gene therapy.

Manufacturing 52

Manufacturing Marketing Patients Safety 52

Map My Customers

AUGUST 2, 2022

Surgical Equipment Sales - This type of rep will be selling specialized surgery equipment that often comes with a high price tag. It identifies the changes in the medical field and enables you to develop and maintain a solid game plan for success.

Medical sales reps 79

Medical sales reps Medical sales Sales Medical 79

pharmaphorum

AUGUST 26, 2022

The US biotech claimed conditional marketing approval from the European Commission for Roctavian (valoctocogene roxaparvovec) as a treatment for adults with severe haemophilia A, who don’t have a history of developing the antibodies that inhibit the activity of blood-clotting protein Factor VIII. million spread over five years.

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FDA Marketing Competition Patients 110

Pharmaceutical Technology

JANUARY 27, 2023

On January 18, Sanofi launched a new warranty program for its rare blood disorder drug Cablivi (caplacizumab), which tackles value-based agreements in a slightly different way. Cablivi stops platelets from clumping together, which prevents small clots, and can be used along with other drugs that suppress the immune system.

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Patients Pharmaceutical Manufacturing Healthcare Provider 52

pharmaphorum

SEPTEMBER 30, 2022

The process starts adding fields to regulatory submission templates that will incorporate re-used information, then building templates with standardized structures and including structured data tags and sources. Fillable metadata is next added to the templates. Donald Palmer, Senior Director, Regulatory Affairs, IQVIA.

Management 52

Management Pharmaceutical Marketing Electronics 52

European Pharmaceutical Review

DECEMBER 27, 2023

Chimeric antigen receptor (CAR) T cells are the first example of a “living drug”. Being a cellular therapy that involves cell manipulation and molecular transfection – and above all, being a living drug – makes CAR T-cell therapy a somewhat challenging immunotherapy to manufacture in‑house.

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Manufacturing Food and Drug Administration Patients Pharma 82

Evolve Your Success

DECEMBER 27, 2022

She helped develop that brand in January 2021. The surgeon’s busy covering the case, and you’re telling me that you even created an avenue to invite representatives that had taken the time to develop a relationship with you to sell to you. You can’t put a price tag on that relationship, especially when you’re like, “I need help.

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Medical sales Medical sales reps Sales Medical 52

Pharmaceutical Technology

NOVEMBER 30, 2022

In what’s being called a “medical bypass”, new anti-obesity drugs are almost matching efficacy rates in weight loss that have previously only been seen with weight loss surgeries. The drug was approved to treat type 2 diabetes mellitus in May. The drug was approved to treat type 2 diabetes mellitus in May. million in Q3.

Medical 105

Medical Manufacturing Insurance Side effects 105

Pharmaceutical Technology

NOVEMBER 30, 2022

In what’s being called a “medical bypass”, new anti-obesity drugs are almost matching efficacy rates in weight loss that have previously only been seen with weight loss surgeries. The drug was approved to treat type 2 diabetes mellitus in May. The drug was approved to treat type 2 diabetes mellitus in May. million in Q3.

Medical 98

Medical Manufacturing Insurance Side effects 98

World of DTC Marketing

JUNE 16, 2021

This includes about one in five who report that they have not filled a prescription or took an over-the counter drug instead, and about one in ten who say they have cut pills in half or skipped a dose. The public sees profits made by pharmaceutical companies as the largest factor contributing to the price of prescription drugs.

Prescription 180

Prescription Government Insurance Pharma 180

Pharma Marketing Network

JUNE 8, 2020

Even there, that’s impacted by some distortions around pbms and how hospitals radically markup those drugs, but that’s probably the one exception. Then long-term, where I think ultimately right and left will meet is an idea that I’m developing around what I call community-owned health plans. Dave (HR): Which part?

Healthcare 40

Healthcare Healthcare Marketing Pharma 40