PM360

MAY 21, 2024

When asked why they didn’t fill a new prescription, the top reasons patients cited were an unwillingness to deal with medication side effects (29%), being unconvinced of their need for the treatment (28%), and not being able to afford the medication (21%).

Patients 52

Patients Prescription Side effects Doctors 52

Pharmaceutical Technology

APRIL 21, 2023

It will pay another $10m in instalments through to September 2024. Blue Water chairman and CEO Joseph Hernandez stated: “With millions of men suffering from BPH and facing adverse side effects associated with current treatments, we are excited to support those patients and make Entadfi readily available for all.

Food and Drug Administration 52

Food and Drug Administration Side effects Distribution Food 52

Pharmaceutical Technology

JUNE 16, 2023

But while available adjunctive options work well, they come at the cost of safety, said Buntinx, and ANT01 could offer these benefits without additional side effects. The company aims to run an interim analysis of the trial by mid-2024 at the very latest.

Food and Drug Administration 52

Food and Drug Administration Side effects Safety Recruitment 52

pharmaphorum

JUNE 23, 2022

It is a challenging proposition, however, as delivery of the therapeutic gene sequences to cells can be difficult and raises the risk of insertion mutations that can lead to side effects, including cancer.

Side effects 80

Side effects Pharma Marketing Patients 80

European Pharmaceutical Review

MARCH 14, 2024

To mark World Kidney Day 2024, Dr Marshall Fordyce, CEO of Vera Therapeutics, spoke with EPR about the challenges of treating kidney diseases, specifically IgAN, a condition caused by dysfunctional B cells. Individuals who receive corticosteroids may experience limited efficacy, alongside significant side effects.

Food and Drug Administration 93

Food and Drug Administration Patients Leads Side effects 93

European Pharmaceutical Review

MARCH 14, 2024

To mark World Kidney Day 2024, Dr Marshall Fordyce, CEO of Vera Therapeutics, spoke with EPR about the challenges of treating kidney diseases, specifically IgAN, a condition caused by dysfunctional B cells. Individuals who receive corticosteroids may experience limited efficacy, alongside significant side effects.

Food and Drug Administration 92

Food and Drug Administration Patients Leads Side effects 92

pharmaphorum

AUGUST 19, 2022

Grünenthal has moved its painkiller resiniferatoxin into phase 3 trials in patients with osteoarthritis, hoping to find an option that sidesteps the side effects and addictive potential of opioid drugs.

Side effects 52

Side effects Recruitment Patients Safety 52

Pharmaceutical Technology

JULY 28, 2022

For example, there are concerns regarding the long wash-out period of LAI products and the management of the side effects that are common with antipsychotic treatment. There are many reasons for lingering resistance around the use of LAI over oral antipsychotics, with individual preferences from both patients and psychiatrists.

Prescription 98

Prescription Side effects Patients Management 98

pharmaphorum

SEPTEMBER 15, 2022

Lying in waits at the moment are well-entrenched therapies like Novartis’ Xiidra (lifitegrast) and AbbVie’s Restasis (cyclosporine), which are not considered to be particularly effective and have side effect issues. Sales were nevertheless solid at $468 million and $1.29 billion respectively last year.

FDA 52

FDA Side effects Prospecting Patients 52

pharmaphorum

OCTOBER 10, 2022

month mPFS with Keytruda plus chemo, with fewer side effects. A key readout for BMS will be a front-line phase 2 study of its combination in NSCLC due to read out in 2024, but its unclear if that could support approval so Immutep could be able to maintain a lead in this type of cancer.

Side effects 56

Side effects Sales Marketing FDA 56

European Pharmaceutical Review

AUGUST 3, 2023

However, the EMA expressed concerns around overall efficacy and, coupled with a concern raised over possible side effects presenting as brain abnormalities suggestive of swelling or bleeding on the brain, led the EMA to the view, following a re-examination process, that it would not recommend the approval of Aduhelm.

Food and Drug Administration 52

Food and Drug Administration Medicine FDA Marketing 52

pharmaphorum

JULY 11, 2022

The company had been eyeing a possible regulatory filing for fitusiran this year, but has now set back the timeline – possibly until 2024 – while it gathers data on the revised dosing schedule, in the hope of maintaining efficacy with fewer clotting side effects.

Engineering 52

Engineering Side effects Competition Sales 52

pharmaphorum

JULY 26, 2022

BROADWAY and BOOKLYN will generate data in 2024, with PREVAIL set to read to in 2026, and if the results are positive will be followed by filings in the US, Europe, China and Japan. So why will obicetrapib avoid the pitfalls of its predecessors?

Side effects 52

Side effects Safety Pharma Patients 52

PM360

SEPTEMBER 21, 2023

A generic here will improve access in OAB to a product with less side effects, which is especially important in the elderly population, Casberg noted. In 2024, ARPA removes the 100% AMP cap. Overactive bladder (OAB) is the final category primped for significant generic competition in 2023, Casberg said.

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Management Manufacturing Sales Competition 105

PM360

APRIL 22, 2024

For example, imagine if a new product in development carries with it transformational efficacy and an uncommon side effect that needs to be carefully managed by a specialty other than the treating specialty.

Education 52

Education Customer Relationship Management Medical science Medical 52

Medico Reach

FEBRUARY 8, 2023

billion during 2020-2024. The Emergence of the Pharmacovigilance Market Medicines and vaccines often have unwanted and severe side effects. Such results call for stringent vigilance on the medicines quality and after-effects, nudging the emergence of the pharmacovigilance market. from 2023 to 2030.

Pharma 52

Pharma Medicine Marketing Prospecting 52

pharmaphorum

DECEMBER 5, 2022

In terms of safety, the CAR-NK was associated with some infusion-related side effects that were manageable and resolved quickly, and there were no cases of neurotoxicity, graft versus host disease (GvHD) or cytokine release syndrome (CRS) – all side effects associated with CAR-T therapies. Those will get underway in 2024.

Side effects 87

Side effects Safety Patients Leads 87

pharmaphorum

SEPTEMBER 14, 2022

For decades, riluzole was the only approved therapy for ALS, with limited efficacy, and it was joined by an intravenous formulation of Radicava in 2017, which according to GlobalData has been hampered by an intense dosing schedule, its route of administration, side effect profile, and high annual cost of therapy.

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Side effects FDA Medical Patients 60

Evolve Your Success

FEBRUARY 13, 2024

At my age, he was like, “You had such a great response to chemo that you have a higher chance of dealing with major issues and potential fatality from radiation side effects in twenty years versus the cancer coming back.” Let’s stick with 2024’s themes. He said he wouldn’t do it. I’m being real.

Patients 64

Patients Sales Medical sales Doctors 64

Pharmaceutical Technology

FEBRUARY 17, 2023

The demand came amid concerns that the drug causes a slew of side effects such as nausea, diarrhea, and liver issues. In 2021, Amgen agreed to conduct a Phase II study (NCT04933695), which is supposed to complete in May 2024, according to Clinicaltrials.gov. However, in some cases, fewer patients could be needed.

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FDA Side effects Pharmacology Patients 115

Pharmaceutical Technology

JUNE 20, 2023

GlobalData forecasts that the market for AI platforms for the entire healthcare industry will reach $4.3bn by 2024, up from $1.5bn in 2019 [i]. Uses include data management, remote surgery, diagnostic and procedural AI assistants, drug discovery, and clinical trial design.

Electronics 52

Electronics Medical Healthcare Healthcare 52