European Pharmaceutical Review

MARCH 14, 2024

To mark World Kidney Day 2024, Dr Marshall Fordyce, CEO of Vera Therapeutics, spoke with EPR about the challenges of treating kidney diseases, specifically IgAN, a condition caused by dysfunctional B cells. Individuals who receive corticosteroids may experience limited efficacy, alongside significant side effects.

Food and Drug Administration 91

Food and Drug Administration Side effects Leads Patients 91

pharmaphorum

AUGUST 19, 2022

Grünenthal has moved its painkiller resiniferatoxin into phase 3 trials in patients with osteoarthritis, hoping to find an option that sidesteps the side effects and addictive potential of opioid drugs. Along with knee osteoarthritis, Grünenthal also plans to test resiniferatoxin in other joints affected by the condition.

Side effects 52

Side effects Recruitment Safety Patients 52

pharmaphorum

JULY 26, 2022

Merck’s exit came after other companies including Pfizer, Eli Lilly and Roche all scrapped CETP development programmes following safety or efficacy issues. BROADWAY and BOOKLYN will generate data in 2024, with PREVAIL set to read to in 2026, and if the results are positive will be followed by filings in the US, Europe, China and Japan.

Side effects 52

Side effects Safety Pharma Patients 52

PM360

SEPTEMBER 21, 2023

A generic here will improve access in OAB to a product with less side effects, which is especially important in the elderly population, Casberg noted. A generic here will improve access in OAB to a product with less side effects, which is especially important in the elderly population, Casberg noted.

Management 105

Management Manufacturing Sales Competition 105

Medico Reach

FEBRUARY 8, 2023

billion during 2020-2024. The Emergence of the Pharmacovigilance Market Medicines and vaccines often have unwanted and severe side effects. Such results call for stringent vigilance on the medicines quality and after-effects, nudging the emergence of the pharmacovigilance market. from 2023 to 2030. from 2023 to 2030.

Pharma 52

Pharma Medicine Marketing Prospecting 52

pharmaphorum

DECEMBER 5, 2022

In terms of safety, the CAR-NK was associated with some infusion-related side effects that were manageable and resolved quickly, and there were no cases of neurotoxicity, graft versus host disease (GvHD) or cytokine release syndrome (CRS) – all side effects associated with CAR-T therapies.

Side effects 87

Side effects Safety Patients Leads 87

Pharmaceutical Technology

FEBRUARY 17, 2023

In January, amidst calls to improve patient safety by optimizing licensed drug formulations, the FDA released a draft guidance that signalled a departure from the most commonly used method of identifying a new therapy’s ideal dosage. For this approach, a “3+3” model is used where a study enrolls three patients into a given dose cohort.

FDA 115

FDA Side effects Pharmacology Patients 115