article thumbnail

Biogen: This train wreck was due

World of DTC Marketing

When George Scangos resigned in 2016, he must have known that the future was bleak. The MS community, which is very active on social media, complained about the side effects of Biogen’s drug while praising new competitors’ drugs. The company was riding high on their MS drugs, but the competition was on the way.

Training 231
article thumbnail

Understanding the evidence used in drug product withdrawals

European Pharmaceutical Review

Our research showed that in Europe between 1999 and 2016, 35 products were withdrawn. Initiatives in the UK such as the Clinical Practice Research Datalink (CPRD), The Health Improvement Network (THIN) and OpenSAFELY support UK, European, and international studies. Meta-analyses contributed least frequently (31.4 2018; 8(1).

Safety 111
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Novel oral chemotherapeutic holds potential for stomach cancer patients

European Pharmaceutical Review

There is an urgent need for more effective chemotherapy treatments with less severe toxicity and side effects. Irinotecan – also known by the brand name Campto/Camptosar ® (Pfizer Ltd.) – has proven to be an effective chemotherapy agent against several types of gastrointestinal cancer. 5): V38-V49.

article thumbnail

How can evidence-based medicine (EBM) methodology support drug withdrawals?

European Pharmaceutical Review

Monitoring and studying the side effects of licensed medicines is an essential part of drug development to ensure public safety. This is usually on a much larger scale than is possible in clinical trials and can uncover less common side effects. Supporting regulators. Study focus. almitrine – a respiratory stimulant.

article thumbnail

Paving the way for anti-Abeta active immunotherapy

European Pharmaceutical Review

While new positive clinical data with anti-Abeta mAbs signal tremendous advancement and proof‑of-concept for the whole field, it is believed that the observed effects could still be improved and optimised in terms of greater clinical benefits, lower side effects and enhanced treatment convenience.

article thumbnail

The case for AI and machine learning in life sciences

Pharmaceutical Technology

Since some drugs and medical products can have severe side effects if used incorrectly, MT engines used to translate such critical information such as dosage instructions, must be checked and edited by human translators. Neural networks learn to “translate” from language A to language B.