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Understanding the evidence used in drug product withdrawals

European Pharmaceutical Review

Our research showed that in Europe between 1999 and 2016, 35 products were withdrawn. Initiatives in the UK such as the Clinical Practice Research Datalink (CPRD), The Health Improvement Network (THIN) and OpenSAFELY support UK, European, and international studies. Meta-analyses contributed least frequently (31.4

Medicine 111
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Novel oral chemotherapeutic holds potential for stomach cancer patients

European Pharmaceutical Review

There is an urgent need for more effective chemotherapy treatments with less severe toxicity and side effects. Irinotecan – also known by the brand name Campto/Camptosar ® (Pfizer Ltd.) – has proven to be an effective chemotherapy agent against several types of gastrointestinal cancer. 5): V38-V49.

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Paving the way for anti-Abeta active immunotherapy

European Pharmaceutical Review

Targeting toxic species of Abeta, such as multimers (with aducanumab and lecanemab) or pyroglutamate Abeta3-42 (with donanemab), induced significant removal of Abeta plaque load in the brains of Alzheimer’s patients, leading to the delay in cognitive decline. Treatment with the mAbs delayed cognitive decline by 2.6 months for lecanemab and 5.5

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The case for AI and machine learning in life sciences

Pharmaceutical Technology

Since some drugs and medical products can have severe side effects if used incorrectly, MT engines used to translate such critical information such as dosage instructions, must be checked and edited by human translators. Neural networks learn to “translate” from language A to language B.