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Novel oral chemotherapeutic holds potential for stomach cancer patients

European Pharmaceutical Review

The availability of oral chemotherapy treatments would provide stomach cancer patients with the option of more efficacious drugs with improved tolerability in a more convenient dosage format” The poor clinical outcomes of stomach cancer make it a key target for drug development. New hope for stomach cancer patients.

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Understanding the evidence used in drug product withdrawals

European Pharmaceutical Review

Our research showed that in Europe between 1999 and 2016, 35 products were withdrawn. They also include many of the common “exclusions” in RCTs, such as pregnant women, children, the elderly and patients on multiple medications. Meta-analyses contributed least frequently (31.4 As of October 2023, 62.93

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How can evidence-based medicine (EBM) methodology support drug withdrawals?

European Pharmaceutical Review

Monitoring and studying the side effects of licensed medicines is an essential part of drug development to ensure public safety. This is usually on a much larger scale than is possible in clinical trials and can uncover less common side effects. Supporting regulators. Study focus. almitrine – a respiratory stimulant.

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Paving the way for anti-Abeta active immunotherapy

European Pharmaceutical Review

Targeting toxic species of Abeta, such as multimers (with aducanumab and lecanemab) or pyroglutamate Abeta3-42 (with donanemab), induced significant removal of Abeta plaque load in the brains of Alzheimer’s patients, leading to the delay in cognitive decline. Treatment with the mAbs delayed cognitive decline by 2.6 months for lecanemab and 5.5

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The case for AI and machine learning in life sciences

Pharmaceutical Technology

Thematic Research [ii] shows that adoption of EMR systems is very high, especially in the US, and CDS systems are leveraging AI technology and available EMRs to provide clinical insight to both physicians and patients. Neural networks learn to “translate” from language A to language B.