pharmaphorum

OCTOBER 3, 2022

Amylyx Pharmaceuticals’ Relyvrio – a new treatment for amyotrophic lateral sclerosis (ALS) approved by the FDA on Thursday, after review of the data from its phase 2 trial – was the next day set at a list price of $158,000 per year in the US, sparking outcry. ALS affects over 30,000 people in the US.

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Pharmaceutical Technology

JANUARY 17, 2023

On January 12, Versanis Bio announced that enrollment had begun for its Phase IIb trial, BELIEVE (NCT05616013), which aims to study bimagrumab’s (BYM-338) efficacy and safety in the US, among other locations. In addition to facilitating loss of fat, the Phase II trial also showed that a lean mass gain of 4.5% was observed in the study.

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World of DTC Marketing

SEPTEMBER 9, 2021

New technologies are being developed that allow for virtual clinical trials and other cost-lowering development costs. A study put a price tag on American’s bad eating habits: $50 billion a year in health care costs, attributable to cardiometabolic diseases such as heart disease, stroke, and type 2 diabetes.

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PM360

OCTOBER 13, 2023

Another capability made possible by fine-tuning is the enhancement of content tagging. Content tagging has always been a labor-intensive task. Auto-tagging ensures that the right content efficiently reaches the right customers. Fine-tuning models can target domains and generate prompts to tag the content into relevant topics.

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pharmaphorum

JANUARY 9, 2023

Zolgensma meanwhile is now approved in 45 countries, with over 2,500 patients treated globally across clinical trials, managed access programs, and in the commercial setting. ” Zolgensma is one of the most expensive therapies available, with a price tag of around $2.1

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Pharmaceutical Technology

MAY 1, 2023

CTH-004 is developed by genetically altering patient T cells for inserting a chimeric antigen receptor (CAR) to target a marker (TAG-72) on ovarian cancer cells and delete genes which are involved in T cell function suppression. Additionally, both the companies will share CTH-004 pre-clinical and clinical data in future.

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Pharmaceutical Technology

DECEMBER 15, 2022

Prior to the development of Camzyos and aficamten, obstructive HCM has not been the target of clinical trial development, so these two therapeutics would benefit a neglected patient population. of sales in 2021 and 2031 respectively. The second highest contributing market is APAC, generating 33.2%

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Pharmaceutical Technology

JUNE 29, 2022

The US Food and Drug Administration (FDA) put a high-profile bluebird bio trial for sickle cell disease on partial clinical hold, and advisory panels deliberated over decisions involving gene therapies for amyotrophic lateral sclerosis (ALS), cerebral adrenoleukodystrophy (CALD), and beta-thalassemia.

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World of DTC Marketing

JUNE 23, 2021

Source: STAT News Our healthcare system can’t continue to support drugs that don’t have good clinical outcomes behind them. Not to mention the $56,000 annual price tag. One agency FDA adviser, resigning from his committee post in protest, called it “probably the worst drug approval decision in recent U.S.

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pharmaphorum

JANUARY 31, 2023

Another factor that impacts trust in pharmaceutical companies is the discrepancy between the efficacy of medications in controlled clinical trials and their effectiveness in real-world use. Given the high price tags placed on many medications, it’s easy to understand why patients often feel that they are being taken advantage of.

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Pharmaceutical Technology

MAY 2, 2023

IO therapies come with a hefty price tag, with ICI therapies in the US typically exceeding $100,000, while cell therapies can exceed $400,000. There is currently a rich and diverse IO pipeline that aims to address these unmet needs, with 703 IO products currently in clinical trials. Cost-related unmet needs also scored highly.

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PM360

APRIL 22, 2024

From defining the target product profile to shaping clinical endpoints and devising asset strategies to crafting scientific narratives, the value of Medical Affairs permeates every aspect of product development. Today, teams are indispensable strategic partners, deeply involved in crafting the very foundation of a product’s journey.

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pharmaphorum

DECEMBER 23, 2022

Here, Richard Staines reports on phase I/II data unveiled at the American Society of Hematology conference that supports further clinical development of inobrodib in multiple myeloma and other blood cancers. Results suggest durable epigenetic re-wiring and provide rationale for intermittent clinical dosing.

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pharmaphorum

AUGUST 21, 2022

There’s no word yet on its pricing, but for comparison Spravato was launched with an annual price tag of around $32,400, which the Institute for Clinical and Economic Review (ICER) concluded was around 25% to 52% too high to be cost effective.

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PM360

APRIL 7, 2023

It’s never too early in the research and development (R&D) process to identify and measure a product’s projected clinical outcomes in order to meet the needs and expectations of payers and healthcare professionals (HCPs) who are the final arbiters of a product’s commercial success. million for the new hemophilia gene therapy.

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pharmaphorum

JULY 25, 2022

It showed an overall response rate with Tecvayli of 63%, including 39% complete responses which is a remarkable result given that the patient recruited into the trial were very ill and heavily pre-treated. Tecvayli previously scored a priority medicines (PRiME) designation from the EMA and a breakthrough-therapy tag from the FDA.

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European Pharmaceutical Review

AUGUST 24, 2022

In total, there are 14 approved ADCs on the global market, all for oncology indications, and over 140 ADCs currently in clinical development. tag ® , inspired by the unique features of microtubule biology and perfectly suited for DAR 2 and DAR 4 ADCs. An ADC combines the specificity of an antibody and the potent power of an anti?cancer

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pharmaphorum

NOVEMBER 24, 2022

Johnson & Johnson’s Spravato therapy for treatment-resistant depression (TRD) hasn’t made the impact the company hoped for in the market, and it is looking to new clinical results to accelerate its take-up. The post J&J builds case for antidepressant Spravato with head-to-head trial appeared first on.

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pharmaphorum

AUGUST 18, 2022

” In clinical trials of the gene therapy, 89% of 41 patients remained free of the need for blood transfusions after a median of 42 months’ follow-up. million price tag attached to the therapy when it was first made available in Europe, and is also well above the proposed $2.1 million, which compares to the $1.7

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Pharmaceutical Technology

APRIL 5, 2023

But access to these treatments continues to remain limited due to high price tags and variable availability across regions. And my estimate is that between 25,000 and 30,000 patients have been treated with those therapies globally, which does not include patients treated in clinical trials.

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PM360

SEPTEMBER 7, 2023

Then onto Tuan Vu, MD, Professor of Neurology, Director, Neuromuscular Division, EMG Laboratories, and ALS Clinic, Department of Neurology University of South Florida, who discussed the global clinical trial. We also put big pull tags on the little pouches that held the items.

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Pharmaceutical Technology

JUNE 21, 2023

The high price tag may be hard to defend , but with lifetime treatment costs for haemophilia B reaching as high as $23m for some, the single-dose treatment could prove far more cost-effective. Despite this, the Institute for Clinical and Economic Review (ICER) claimed that a fairer price would be in the region of $2.9m.

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pharmaphorum

OCTOBER 4, 2022

During the first stage of the initiative, more than 2,000 research papers were published, 49 clinical trials were carried out, and more than 30 patents were filed through the support of the US National Cancer Institute (NCI). These datasets are critical as a means to identify how molecular information affects clinical outcomes.”

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Map My Customers

AUGUST 2, 2022

Surgical Equipment Sales - This type of rep will be selling specialized surgery equipment that often comes with a high price tag. If you are a pharmaceutical sales rep, do your research on the background of the medications, stay up-to-date on the newest clinical trials, etc.

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European Pharmaceutical Review

JULY 11, 2022

Funding of up to $30 million will support vaccine design, its development through Phase I trials and regulatory activities. . These coronavirus RBDs are attached to a nanoparticle by protein tags, enabling the structure to display fragments from multiple viruses on a single nanoparticle. . The innovative protein ?“glue”

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Evolve Your Success

DECEMBER 27, 2022

They are inspecting and ensuring that all of these instruments that we use, whether we’re talking about using it in the OR, labor and delivery, wound care clinic, or anywhere where you might need an instrument that is clean or sterile, they are the ones making sure that instrument is exactly like it needs to be. Let’s go back to you then.

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European Pharmaceutical Review

DECEMBER 27, 2023

2,3 Clinical implementation of CAR T-cell technology requires a reproducible T-cell manufacturing platform, which necessitates effective gene-transfer tools and T-cell culture conditions. 6-8 Clinical recommendations also change. This is in addition to its considerable price tag.

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Pharmaceutical Technology

NOVEMBER 30, 2022

“Bariatric surgeries show 30% weight loss in the first year and 25% weight loss in the long term,” says Papamargaritis, while that the clinical data for Mounjaro shows that the drug leads to a 16–22.5% One highly anticipated study is Mounjaro’s SURMOUNT-MMO Phase III clinical trial. billion in 2022 alone to expand capacity.

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Pharmaceutical Technology

NOVEMBER 30, 2022

“Bariatric surgeries show 30% weight loss in the first year and 25% weight loss in the long term,” says Papamargaritis, while that the clinical data for Mounjaro shows that the drug leads to a 16–22.5% One highly anticipated study is Mounjaro’s SURMOUNT-MMO Phase III clinical trial. billion in 2022 alone to expand capacity.

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Pharma Marketing Network

JUNE 8, 2020

I mean, you know, there has obviously been a lot of breakthrough biologics and different therapeutics like around cancers and things like that, that have high price tags because maybe they don’t have as big a market as you know, something’s wrong, you know blood pressure medication. So yeah, there is plenty to talk about there.

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