Wed.Jul 20, 2022

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Healthcare doesn’t give a damn about patients

World of DTC Marketing

A new analysis released Wednesday by Patients for Affordable Drugs estimates that pharmaceutical companies in the U.S. have raised drug prices 1,186 times so far this year. But they’re not alone. Health insurers in individual marketplaces across 13 states and Washington D.C. will raise rates an average of 10% next year, according to a review of rate filings by the Kaiser Family Foundation.

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Elevating patient care from the home

MedCity News

By adding adherence and connectivity capabilities to home-based solutions, clinicians can maintain open lines of communication with patients, helping patients better care for themselves from the comfort of their homes.

Patients 144
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Trending Sources

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Connecting your Digital Health Strategy from Clinical to Commercial

PharmExec

Thursday, July 21st 2022 at 11am EST, 8am PST, 5pm CEST Join this webinar to hear industry thought leaders discuss how data and experiences serve clinical and commercial needs, explore which platforms and technologies can enable a robust digital health ecosystem, and share recommendations for building a digital health strategy fit for your business.

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There’s a spotlight on nurses’ poor mental health, but little action is actually being taken

MedCity News

The healthcare industry is certainly having a conversation about nurses’ mental health, but actual action to address wellbeing concerns among these burnt out workers is lagging, according to a new report. To effectively address nurses’ mental health struggles, providers must focus on benefits that make nursing a more sustainable career choice, such as offering flexible scheduling and wellness stipends.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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Prescribing shift for Pfizer’s Paxlovid expands access but draws questions

Pharmaceutical Technology

A key factor of Pfizer’s Covid-19 antiviral Paxlovid efficacy has been early intervention, but getting it in time has proven to be a challenge. On 6 July, in an effort to accelerate access, the US Food and Drug Administration (FDA) allowed pharmacists to also begin prescribing the drug to eligible individuals with Covid-19. Previously, only licensed and authorised physicians, advanced practice registered nurses, and physician assistants could prescribe the drug. .

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UK scientists say they have found cancer driver in junk DNA

pharmaphorum

It has suspected for many years that some diseases may be linked to non-coding or ‘junk’ DNA, but the mechanism behind the pathology hasn’t been worked out. Now, scientists in the UK think they have found a culprit implicated in cancer. Junk DNA is a term used to describe the 97% of the genetic sequence in human cells found between the 3% coding for our 20,000 genes, once thought to be inert.

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More Trending

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Meeting the quadruple aim through whole-person care

MedCity News

Covid-19 exposed how unhealthy we are as a nation making the case for whole-person care even stronger. All we need now is to focus on redesigning our health care system to deliver this type of care—and muster the courage to do it.

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The Future of Medical Sales

MaBiCo

The Future of Medical Sales. The profession of medical sales has clearly faced a decline during the last years, making many professionals feeling anxious about the prospect of their careers. Pharmaceutical companies of every size, cut on their medical sales teams to achieve economies and reduce their costs. Many medical reps worry that the best days of their profession are behind and worry that in the long run it’s going to extinct like many other professions of the past.

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MedCity Pivot podcast: Using virtual-first care to improve the patient and clinician experience [Sponsored]

MedCity News

The Covid-19 pandemic has propelled virtual healthcare into our daily lives, although the quality of that experience varies. But one emerging trend from the scaling of telehealth is virtual-first care, as Wheel CEO and founder Michelle Davey explained.

Patients 103
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NA to NAM ratio as a biomarker for cell therapy sterility

European Pharmaceutical Review

Researchers have shown that ratio of nicotinic acid (NA) to nicotinamide (NAM) in cell cultures significantly increases with the presence of live microorganisms within 24 hours, acting as a useful biomarker for the detection of early-stage microbial contamination in cell therapies. Cell therapies are emerging as promising therapeutic modalities across a range of indications, with mesenchymal stromal cells (MSCs) the most clinically studied cell therapy platform worldwide; however, the nutrient r

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Don’t miss the MedCity INVEST PharmaTech virtual conference July 26

MedCity News

The conference highlights the convergence of digital health and drug development. Among the panel discussions are a focus on the state of AI in drug discovery and the future of digital medicines. A startup pitch contest spotlights companies seeking to improve clinical trials. Register for free today!

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Nanoparticle Vaccine for Many SARS-Like Coronaviruses

Medgadget

Researchers at the California Institute of Technology, better known as Caltech, have developed a nanoparticle vaccine that appears to confer broad protection against SARS-like betacoronaviruses. This includes SARS-CoV-2, responsible for the current pandemic, and SARS-CoV, which caused the original SARS pandemic in the early 2000s. The vaccine consists of protein nanoparticles that are studded with spike protein elements of eight different SARS-like betacoronaviruses, including SARS-CoV-2, but th

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4 things health systems must do to thrive amid economic uncertainty

MedCity News

In order for providers to thrive in healthcare’s new landscape, they will have to prioritize agility and new business building, according to a new McKinsey report. This means health systems must prioritize efficiency, be quicker with their decision making, think about capital allocation differently and pursue strategic growth initiatives.

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Dissociating Tissue into Single Cells Using Electric Fields

Medgadget

A team of scientists at Brown University has developed a technique that allows them to rapidly dissociate a tissue sample into individual cells. The approach involves placing a tissue sample, such as a tumor biopsy, between two electrodes. Electric field fluctuations then help to pull the cells in alternating directions, eventually culminating in their dissociation.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Morgan Health’s $30M investment in Centivo to power alternative health plan focused on VBC

MedCity News

Centivo Health is a health plan that only sells to self-funded employers. Morgan Health chose to invest in the company because of its focus on providing low-cost coverage.

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Cancer Research UK partnership aims to back 10 new startups

pharmaphorum

Cancer Research UK has expanded an alliance with investment group Deep Science Ventures with a commitment to support the formation up to 10 new oncology startups. London-based DSV has been working since 2019 with the charity’s Cancer Research Horizons unit, an incubator organisation which was set up to nurture new discoveries in academia and help to bring them to patients.

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How can evidence-based medicine (EBM) methodology support drug withdrawals?

European Pharmaceutical Review

Withdrawing drugs over safety concerns requires careful analysis of the health benefits and risks by regulators. 1 But while data on adverse reactions is rightly used to help with these decisions, there is currently no additional modelling on the positive impact regulatory action could have on public health. Our research paper, which is being submitted for publication this summer, aims to create an evidence-based medicine (EBM) methodology that can assess this positive impact, to further help re

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Woman of the Week: Vaxxinity's Mei Mei Hu

PharmaVoice

Mei Mei Hu is looking to lead a third biologic ‘revolution’ by developing vaccines for chronic diseases.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Aardex and Biocorp recruited by Trials@Home for phase 4 diabetes study

PharmaTimes

The decentralised clinical trial centre will combine Biocorp pen injector with Aardex’s software

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By the numbers: The rising danger of superbugs

PharmaVoice

A look at how the COVID-19 pandemic exacerbated one of the world’s greatest public health concerns.

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TSB and CR Pharma partner for Covid-19 antibody therapy in China

Pharmaceutical Technology

TSB Therapeutics, a joint venture (JV) majority-owned by Brii Biosciences (Brii Bio), has entered a collaboration with China Resources Pharmaceutical Commercial Group (CR Pharma) for the commercialisation of an antibody therapy, amubarvimab/romlusevimab combination, for Covid-19 in China. . Brii Bio developed the combination therapy in partnership with Tsinghua University and the 3rd People’s Hospital of Shenzhen.

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Healthcare as a B2B Market

Scott’s Directories

The healthcare industry has exponentially advanced in recent years. Competition among market names is one factor that resulted in the rapid growth of the healthcare industry. But more than the competition, the advanced technology has resulted in an overnight shift. The data that is derived from such technology, such as the Ontario physician directory , is used by many marketers to improve their marketing strategies and consequently increase B2B sales.

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

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Allowing You to do More with Less: The TRS100 Transmission Raman System

PharmaTech

Thursday, ????July 21st, 2022 at 11am EDT|8am PDT|4pm BST|5pm CEST Learn about the use of molecular spectroscopy techniques – transmission Raman spectroscopy (TRS) and laser direct infrared (LDIR) – for solid-state analysis in pharmaceutical formulation development.

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CAMP4 raises $100m to take lead RNA drugs into clinic

pharmaphorum

Armed with a $100 million second-round financing, CAMP4 Therapeutics is preparing to start the first clinical trial of a drug targeting regulatory RNA (regRNA) molecules that can be used to fine-tune the expression of genes. The Cambridge, Massachusetts biotech has discovered that areas of the non-coding parts of the human genome – referred to by its chief executive Josh Mandel-Brehm (pictured above) as the “dark side” of the genome – actually produce regRNAs that control the express

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The Challenges of Safety Risk Detection: The Automation Solution

Pharmaceutical Commerce

If there’s anything we learned from the pandemic, it’s the critical need to analyze patient outcome data in real time to stay informed on the safety and efficacy of treatments in the real world.

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Out Of Office Medical Sales

Medical Sales Authority

Lets be honest. Vacation is my favorite time of the year. Sunny skies and beaches. I always love and look forward to my time away from work. But a nice rejuvenating vacation takes some preparation and work. I am going to share the out of office medical sales tips I have learned over the years. What Is A Good Out Of Office Automatic Reply? Fist off, you need to set an informative and automatic out of the office email.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Court won’t raise Seagen damages award in Enhertu patent dispute

pharmaphorum

A Texas court has confirmed the $41.8 million damages awarded to Seagen in its patent dispute with Daiichi Sankyo over beast cancer drug Enhertu, but declined to raise the sum despite concluding that the infringement was ‘wilful’ Seagen won a lawsuit in April which claimed that Enhertu (trastuzumab deruxtecan) infringes a patient it holds (No. 10,808,039) covering antibody-drug conjugates that include auristatin compounds coupled to an antibody via a linker molecule.

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Internet of things hiring levels in the pharmaceutical industry rose to a year-high in June 2022

Pharmaceutical Technology

The proportion of pharmaceutical companies hiring for internet of things related positions rose in June 2022 compared with the equivalent month last year, with 19.8% of the companies included in our analysis recruiting for at least one such position. This latest figure was higher than the 15.8% of companies who were hiring for internet of things related jobs a year ago and an increase compared to the figure of 19% in May 2022.

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The big squeeze?

pharmaphorum

With NHS England highlighting savings of £1.2 billion on medicines in three years coming from both deals on generics and new innovative treatments, Leela Barham takes stock of what we know about the impact on spending. As industry raises concerns about the multiple ways spend is managed – unsaid but pointing to a big squeeze on drug spending – she argues that industry will need to put together a strong evidence-based case to achieve change.

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How to Promote a Culture of Belonging in Pharmacy

Pharmacy Times

Companies that incorporate Diversity, Equity, and Inclusion (DEI) into their everyday operations will be instrumental in shaping a new standard in their workforce and ultimately in society.

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The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.