Thu.Feb 01, 2024

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Who's No. 1? With $25B in sales, Merck's Keytruda looks to be the top-selling drug of 2023

Fierce Pharma

With Merck reporting a whopping $25 billion sales haul for | With Merck reporting a whopping $25 billion sales haul for Keytruda on Thursday, the PD-1 cancer superstar appears to be the world’s top-selling drug in 2023. Keytruda looks set to take over the top spot from Pfizer and BioNTech’s Comirnaty, which ruled the previous two years, scoring sales of $55.9 billion in 2022 and $55.1 billion in 2021.

Sales 285
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Cigna MA Sale to HCSC Could Still Clear Way for Humana Acquisition, Expert Says

MedCity News

Despite Cigna and Humana ditching their pursuits to combine in December, one industry expert believes there’s still a chance after Cigna announced its plan to sell its Medicare Advantage business to Health Care Service Corp.

Sales 118
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Merck still in the market for deals in the $1B to $15B range, CEO says

Fierce Pharma

Even after the acquisitions of Prometheus and Acceleron, Merck is ready to make more deals in the $1 to $15 billion range, according to CEO Rob Davis.

Marketing 291
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Telehealth, Patient Reviews, and Retailization – 2024 Healthcare Digital Marketing Trends

MedCity News

To meet evolving consumer expectations, providers must have a strong digital marketing strategy and user experience online. Here are 5 healthcare marketing trends to pay attention to in 2024.

Retail 110
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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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In Medicare negotiation process, HHS sends 1st price offers as industry blasts lack of transparency

Fierce Pharma

Despite litigation and denouncements from the biopharma industry, Medicare price negotiations under the Inflation Reduction Act are rolling on. | Despite litigation and denouncements from the biopharma industry, Medicare price negotiations under the Inflation Reduction Act are rolling on. And today, the government is sending out its first round of offers on affected drugs.

Biopharma 256
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Takeda Puts Up $300M to Partner on Protagonist Drug for Rare Blood Disease

MedCity News

Protagonist Therapeutics’ rusfertide could have preliminary data next year from its Phase 3 test in polycythemia vera. If the peptide drug wins FDA approval in this rare blood disorder, the partners will share in U.S. commercialization while Takeda is responsible for the drug in the rest of the world.

FDA 105

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Active Listening In Sales: the Missing Element To Selling Success

Integrity Solutions

Is sales still a viable profession today? Is it something needed or that people even want to do? Many who are currently in sales positions or are considering a role in sales are beginning to question what the job really means today and whether it’s one they can be proud of — especially when it feels like their whole purpose can feel like it’s to pressure or coerce buyers into doing something.

Sales 106
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Despite Roche's sharp COVID sales decline, eye drug Vabysmo powers major revenue win, CEO says

Fierce Pharma

As Roche CEO Thomas Schinecker sees it, the Swiss pharma made a “major achievement” in 2023. Despite a sharp decline in COVID-related sales, the company was able to grow overall revenues | As Roche CEO Thomas Schinecker sees it, the Swiss pharma made a “major achievement” in 2023. Despite a sharp decline in COVID-related sales, the company was able to grow overall revenues thanks in large part to the performance of eye disease drug Vabysmo.

Sales 234
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Lundbeck study knocks confidence in alpha-syn as CNS target

pharmaphorum

A phase 2 trial of Lundbeck’s alpha-synuclein-targeting drug Lu AF82422 has failed to reach statistical significance in patients with multiple system atrophy (MSA), although the company says there are encouraging “signals of efficacy” in the data.

Patients 103
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GSK inks another Zantac settlement ahead of trial in California

Fierce Pharma

After GSK spent the latter half of 2023 warding off concerns about the swelling Zantac product liability litigation, the company is back at the settlement table in 2024. | After GSK spent the latter half of 2023 warding off concerns about the swelling Zantac product liability litigation, the company is back at the settlement table in 2024.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Look Beyond GPOs for a New World of Cost Savings

MedCity News

There’s a common belief in the healthcare industry that partnering with Group Purchasing Organizations (GPOs) means that most or all non-clinical purchases are covered by the contract. It almost sounds too good to be true: GPOs have all the answers for all your procurement needs. Finally, a one-stop shop for all your procurement solutions! Unfortunately, this is far from reality.

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Despite Vyvanse’s loss of exclusivity, Takeda treads water thanks to launch momentum

Fierce Pharma

Despite the recent loss of exclusivity on Takeda's ADH | As Vyvanse generics take a chunk out of Takeda's sales, the company is hopeful its roster of new drugs, including its dengue fever vaccine Qdenga, can keep revenues intact.

Sales 214
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Cohere Health Snags $50M to Speed Up Prior Authorization

MedCity News

Prior authorization software startup Cohere Health raised $50 million on Thursday, bringing its total funding to $106 million. The need for software to streamline the prior authorization process is perhaps more evident than ever given CMS’ new rule on the matter.

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4 Ways to Bring Greater Precision to Oncology Omnichannel Experiences

Fierce Pharma

Cultivating Connections: Continuity in Patient Engagement | 4 Ways to Bring Greater Precision to Oncology Omnichannel Experiences

Patients 164
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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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CCC President & CEO Tracey Armstrong Wins 2024 BIG Innovation Award

Copyright Clearance Center

February 1, 20 24 – Danvers, Mass. – CCC , a leader in advancing copyright, accelerating knowledge, and powering innovation, announces that its President and CEO, Tracey Armstrong , was named a winner of the 2024 BIG Innovation Award recognizing organizations, products, and people bringing new ideas to life in innovative ways and presented by Business Intelligence Group.

Leads 98
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Turning information into outcomes with MedThink Communications

Fierce Pharma

“We have a vision, which is to close the gap between scientific knowledge and clinical practice.” | Experienced healthcare communications expert and MD of MedThink Communications John Kane discusses the importance of physician knowledge of the patient’s psychosocial status on treatment plans and outcomes.

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Coordination of Benefits: An Overlooked Pillar of Medicaid Programs

MedCity News

Coordination of benefits is a critical pillar of the Medicaid program as it ensures the efficient use of resources, prevents overutilization, promotes equity in resource distribution, mitigates fraud and abuse, contributes to program longevity and ultimately enhances healthcare access for beneficiaries.

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Fierce Pharma Asia—Takeda's $300M deal; Lonza's plant closure; US bill targets certain Chinese firms

Fierce Pharma

Takeda paid $300 million upfront to license a blood disorder candidate. Lonza will close a biologics plant in China. A U.S. draft bill targets several Chinese biotech companies. And more. | Takeda paid $300 million upfront to license a blood disorder candidate. Lonza will close a biologics plant in China. A U.S. draft bill targets several Chinese biotech companies.

Pharma 130
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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KOL Engagement Trends Webinar

Impetus Digital

Register for one of Impetus’ upcoming webinars between February 26-28: Top-5 Trends in Virtual KOL Engagement About the webinar We’re taking a look at the top trends from 2023 and share our predictions for the new year. Our expert speakers will share their unique industry insights and the “best of the best” virtual collaboration and insight-gathering programs from 2023.

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Protecting Commercial AI Rights is Harder than You Think — EU Edition

Copyright Clearance Center

Legislation often lags technological advances. The EU's Digital Single Market Copyright Directive leaves many open questions regarding AI text- and data-mining.

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Personalized Medicine Is Revolutionizing the Role of Pharma Companies in the Healthcare Landscape

MedCity News

The more pharma companies do to become service providers in the personalized medicine era, the more they’ll succeed and the more lives they’ll help to save.

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Keytruda remains Merck & Co’s biggest 2023 success story as patent expiry looms

Pharmaceutical Technology

Merck & Co (MSD) has reported a 1% revenue increase from 2022, and may face setbacks in the next few years from top-selling drugs.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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BCMA CAR T therapy facilitates potential autoimmune breakthrough

European Pharmaceutical Review

Positive results from the first global study for chimeric antigen receptor (CAR)-antologous T cell (BCMA CAR T) injection (Equecabtagene Autoleucel) in immune-mediated necrotising myopathy (IMNM), suggest that the cell therapy could provide a new therapeutic option for antibody-mediated autoimmune disorders. the cell therapy could provide a new therapeutic option for antibody-mediated autoimmune disorders” IMNM is an autoimmune-mediated skeletal muscle disorder belonging to an idiopathic i

Safety 85
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Almirall, Microsoft team up on digital dermatology drive

pharmaphorum

Almirall has formed a three-year alliance with Microsoft designed to accelerate the discovery and development of personalised dermatology therapies.

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Novartis reports 62% rise in FY 2023 net income

Pharmaceutical Technology

Novartis has announced net income soaring by 62% to $8.6bn for the full year 2023 (FY 2023) from the previous year’s $6.04bn.

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Cancer treatment could identify patients most likely to respond to cancer drugs

PharmaTimes

Tumours with high mtDNA mutations more likely to respond to Opdivo

Patients 113
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Takeda grabs late-stage haematology drug from Protagonist

pharmaphorum

Takeda licenses late-stage polycythemia vera drug candidate rusfertide from Protagonist Therapeutics, adding to its rare blood disorder pipeline.

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Millions of people to view digital prescriptions via the NHS app

PharmaTimes

Prescriptions ordered via the app are expected to save around 1.

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Navigating the Challenges of Biopharma Product Launches: A Blueprint for Success

PM360

Embarking on the journey from product development to market success in the biopharma industry is no small feat. The landscape is highly competitive with new prescription medications launching worldwide each year. However, this journey is fraught with challenges as revealed by an in-depth analysis. According to a McKinsey report , a startling 40% of biopharma products fail to meet their sales forecasts within the initial two years, prompting a critical reassessment of strategies for product launc

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DELFI Diagnostics Launches Assay That May Improve Monitoring of Cancer Treatment Response

PharmExec

DELFI-Tumor Fraction assay was developed to improve noninvasive assessment of tumor burden and monitoring of treatment efficacy and resistance in patients with advanced cancers.

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.