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Evaluation of Procipient ®(Dimethyl Sulfoxide USP, PhEur ) in Topical Dosage Form Formulations

PharmaTech

Procipient ® (Dimethyl Sulfoxide USP, PhEur ) is the only compendial DMSO specifically for pharmaceutical use. Procipient is supported with the proper documentation required by pharmaceutical regulatory authorities.

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Aragen to Invest in New Formulation Manufacturing Facility in Hyderabad, India

PharmaTech

Aragen’s new 12,000 ft² facility will include various dosage form capabilities, including oral solids, liquids, topicals, and films.

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QA of prostaglandin analogues for glaucoma treatment

European Pharmaceutical Review

The paper suggested low bioavailability after topical ophthalmic administration is evidence of the need for more effective molecules, as well as formulations that target sites more precisely. Developments need to be made to enable lower dosages and toxicity, limit adverse effects and find better treatment efficacy of ocular drugs, it stated.

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Roquette opens pharmaceutical innovation facility in Pennsylvania, US

Pharmaceutical Technology

The facility complements the company’s current pharma innovation centres in France and Singapore, and intends to improve the patient experience with modern oral dosage forms. Situated at the hub of the country’s northeastern pharmaceutical corridor, the new facility is staffed by research, application and formulation specialists.

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First-in-class plaque psoriasis oral therapy approved in EU

European Pharmaceutical Review

Dosage for Otezla was 30mg twice daily. Nearly one-quarter of people with psoriasis have moderate to severe forms of the condition. Current therapies include topicals, orals and biologics. In both studies, Sotyktu was given as 6mg once daily compared to placebo.

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Enhancing bioavailability in ocular drug delivery

European Pharmaceutical Review

Currently, effective topical administration is challenging as the industry aims to prolong drug residence time and guarantee appropriate ocular permeation. How to enhance ocular drug bioavailability One approach to enhance drug bioavailability after topical administration is increasing corneal permeability.

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Healthcare Watch December 2023

PM360

A standard dose of the medicine causes acute kidney damage in 20% of patients and 50% of those who receive higher dosages used to treat life-threatening infections on a broad spectrum. The downside to this potent drug is it can be quite toxic and poses risks to the human body even in small doses.