World of DTC Marketing

JUNE 23, 2021

I always thought if there were questions about efficacy or treatment, we should be overly cautious and inform our customers (patients). Not to mention the $56,000 annual price tag. When I didn’t understand something, I went to the medical people on the team to gain insights.

FDA 218

FDA Side effects Physicians Patients 218

pharmaphorum

AUGUST 25, 2022

J&J’s first-mover advantage is likely to translate into a market-leading position unless newer drugs can show a significant advantage in safety or efficacy, according to GlobalData, which says the new drug will probably encroach on some of the CAR-T therapies’ territory.

FDA 95

FDA Marketing Safety Patients 95

pharmaphorum

AUGUST 21, 2022

There’s no word yet on its pricing, but for comparison Spravato was launched with an annual price tag of around $32,400, which the Institute for Clinical and Economic Review (ICER) concluded was around 25% to 52% too high to be cost effective.

FDA 91

FDA Marketing Pharma Sales 91

Pharmaceutical Technology

MAY 1, 2023

CTH-004 is developed by genetically altering patient T cells for inserting a chimeric antigen receptor (CAR) to target a marker (TAG-72) on ovarian cancer cells and delete genes which are involved in T cell function suppression. Shunxi will also hold an option to negotiate rights to other CAR-T products, which include the licenced IP.

Manufacturing 52

Manufacturing Patients Leads Pharmaceutical 52

pharmaphorum

DECEMBER 12, 2022

She told ASH that current therapies for ITP have limitations, including tolerability issues, lacklustre efficacy and a short duration of effect, as well as having a limited impact on quality of life.

Side effects 52

Side effects Sales Competition Patients 52

Pharmaceutical Technology

FEBRUARY 10, 2023

This is not the first treatment to come with a high price tag. Access to oncology medicines varies across countries, and their cost against safety/efficacy is generally perceived as being low, such as in the US. million, according to GlobalData’s Price Intelligence (POLI), making it the most expensive drug in the world.

Marketing 105

Marketing Medicine Leads Safety 105

pharmaphorum

DECEMBER 23, 2022

But along with strong efficacy come some considerable risks and costs: cytokine release syndrome (CRS), where a patient’s immune system becomes dangerously over-stimulated, and neurotoxicity are potential side effects that need to be managed.

Side effects 52

Side effects Patients Medical Medicine 52

European Pharmaceutical Review

NOVEMBER 10, 2022

With the new modalities used to treat disease and address previously undruggable targets, advanced drug delivery systems are critical to ensure targeted delivery, and to maximise safety and efficacy. Target engagement (efficacy) – cellular uptake and cytoplasmic/nuclear delivery of cargo is a major bottleneck for clinical translation.

Medicine 97

Medicine Distribution Engineering Electronics 97

pharmaphorum

JANUARY 31, 2023

Another factor that impacts trust in pharmaceutical companies is the discrepancy between the efficacy of medications in controlled clinical trials and their effectiveness in real-world use. Given the high price tags placed on many medications, it’s easy to understand why patients often feel that they are being taken advantage of.

Patients 52

Patients Pharma Side effects Education 52

European Pharmaceutical Review

AUGUST 24, 2022

tag ® , inspired by the unique features of microtubule biology and perfectly suited for DAR 2 and DAR 4 ADCs. Selective Generation of Efficacious Antibody–Drug Conjugates. Antibody-drug conjugates: challenges, solutions and future potential… Pushing the boundaries of ADC design. Tubulis’ second technology platform is called Tub?tag

Engineering 84

Engineering Side effects Marketing Patients 84

Pharmaceutical Technology

APRIL 13, 2023

Although the findings in the report are only preliminary, they shed light at the considerations behind the high price tags of gene therapies. Sickle cell disease is an inherited blood disorder that is caused by mutations in the HBB gene, which codes for the oxygen-carrying protein haemoglobin in red blood cells.

Healthcare 59

Healthcare Healthcare Pharmaceutical FDA 59

Pharmaceutical Technology

JULY 14, 2022

The commercial investment required to research and develop an innovative drug, prove its safety and efficacy, and bring it to market is staggering. These countries will have a smaller patient pool due to population size and will likely carry a price tag that is significantly below that of higher GDP countries.”.

Medicine 59

Medicine Marketing Specialization Pharma 59

European Pharmaceutical Review

JULY 11, 2022

We are delighted to be working with CEPI to further this nanoparticle technology with the goal of producing efficacious, low-cost, infrastructure-independent vaccine that will be accessible to low- and middle-income countries.” . How the novel coronavirus vaccine works. The innovative protein ?“glue”

Manufacturing 94

Manufacturing Engineering Leads Medicine 94

European Pharmaceutical Review

DECEMBER 27, 2023

Currently CAR T-cell therapy is approved for three indications: acute lymphoblastic leukaemia (ALL), non-hodgkin lymphoma (NHL), and multiple myeloma (MM) – and the strongest correlation between CAR T-cell efficacy and persistence has been demonstrated in ALL. This is in addition to its considerable price tag.

Manufacturing 85

Manufacturing Food and Drug Administration Patients Pharma 85

Pharmaceutical Technology

NOVEMBER 30, 2022

In what’s being called a “medical bypass”, new anti-obesity drugs are almost matching efficacy rates in weight loss that have previously only been seen with weight loss surgeries. Mounjaro is the first weight loss drug to show efficacy rates comparable to surgical procedures like sleeve gastrectomies. compared to a 5.1%

Medical 105

Medical Manufacturing Insurance Side effects 105

Pharmaceutical Technology

NOVEMBER 30, 2022

In what’s being called a “medical bypass”, new anti-obesity drugs are almost matching efficacy rates in weight loss that have previously only been seen with weight loss surgeries. Mounjaro is the first weight loss drug to show efficacy rates comparable to surgical procedures like sleeve gastrectomies. compared to a 5.1%

Medical 98

Medical Manufacturing Insurance Side effects 98

PM360

APRIL 7, 2023

Importance of Data Collection Many manufacturers fail to allocate sufficient time to obtain the safety and efficacy data needed to define critical endpoints. The accumulation of the right data—including safety, efficacy, and outcomes—are vital to negotiations with payers as opposed to what regulators are looking for.

Manufacturing 52

Manufacturing Marketing Patients Safety 52

PM360

APRIL 22, 2024

Greater reliance on data to enhance stakeholder engagement efficacy will drive the need for pharmaceutical organizations to propel data-driven techniques across Medical Affairs functions such as Medical Communications, Medical Information, Medical Education, etc.

Medical 52

Medical Healthcare Healthcare Education 52

Pharmaceutical Technology

APRIL 5, 2023

But access to these treatments continues to remain limited due to high price tags and variable availability across regions. Currently, all approved CAR-T therapies are autologous, where T cells taken from patients are modified and then re-infused.

Food and Drug Administration 59

Food and Drug Administration Engineering Patients Education 59