European Pharmaceutical Review

JANUARY 11, 2024

The current medications (opioid and non-opioid) often force the patients to make an unfortunate choice between efficacy and debilitating side effects, leading to a cycling through multiple different therapies and suboptimal treatment response. The present unmet needs within chronic pain are not met with opioid therapies. Pain and Therapy.

Medicine 87

Medicine Pharmacology Management Side effects 87

European Pharmaceutical Review

JANUARY 19, 2024

An important advance in treating breast cancer The pharmaceutical company shared that its oral small molecule poly (ADP-ribose) polymerase (PARP) inhibitor is indicated in adults who have had an anthracycline or a taxane, or both, if suitable, and endocrine therapy in patients with hormone receptor (HR)-positive breast cancer, if suitable.

Pharmacology 92

Pharmacology Patients Pharmaceutical Medicine 92

European Pharmaceutical Review

FEBRUARY 27, 2024

Leading the MHRA – a five year journey Professor Graham Cooke, interim chair of the MHRA board, remarked that Dame June’s “leadership of the MHRA over the last five years, particularly during the COVID-19 pandemic, has been exceptional.” The post MHRA Chief Executive to step down appeared first on European Pharmaceutical Review.

Pharmacology 104

Pharmacology Safety Medicine Education 104

Contrarian Sales Techniques

DECEMBER 5, 2023

Did you know that a well-trained pharmaceutical sales rep can be the driving force behind a healthcare provider's decision-making process? In the complex world of pharmaceuticals, it’s not just what you sell, but how you sell it. In this post, we’re diving deep into the realm of pharmaceutical sales training. That’s right.

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Pharmaceutical Sales Training Sales Pharmaceutical 52

European Pharmaceutical Review

MAY 9, 2023

NK cell functionality was restored in participants following gold-standard pharmacological obesity GLP-1 analogue treatment, according to a study published in Obesity. appeared first on European Pharmaceutical Review. This may contribute to the benefits reported with these medications in people with obesity, the data showed.

Pharmacology 112

Pharmacology Leads Medical Pharmaceutical 112

European Pharmaceutical Review

JULY 13, 2023

This could lead to significant research waste. 7,8,9 This work will ultimately form the basis of our understanding of which combination of these compounds may make the best pharmaceutical agent to take forward into clinical trials for these disease areas. Expert Review of Clinical Pharmacology. British journal of pharmacology.

Medical 93

Medical Food and Drug Administration Pharmacology Medicine 93

European Pharmaceutical Review

MARCH 9, 2023

Highly potent active pharmaceutical ingredients (HPAPIs) are used in formulations for high potent drugs, owing to their ability to target precise disease cells including cancer cells. ” Highly potent APIs are pharmacologically and biologically active compounds at low doses. appeared first on European Pharmaceutical Review.

Safety 97

Safety Pharmacology Training Manufacturing 97

Pharmaceutical Technology

NOVEMBER 17, 2022

This delay in diagnosis ultimately leads to disease progression and associated complications, such as chronic pelvic pain and infertility, which greatly affects the patients’ quality of life. The post NICE to update endometriosis guidelines to improve diagnosis and surgical management appeared first on Pharmaceutical Technology.

Management 102

Management Pharmacology Side effects Patients 102

Pharmaceutical Technology

OCTOBER 20, 2022

We are well positioned to build a leading mechanistic-based oncology company that brings promising science to cancer patients with drug-resistant tumours.”. Allosteric modulation of eIF4E provides various advantages to prior methods and targets several drivers of pharmacology at the same time.

Pharmacology 52

Pharmacology Leads Pharmaceutical Patients 52

Pharmaceutical Technology

FEBRUARY 16, 2023

Merck will be responsible for leading the preclinical pharmacology and biology trials. The post Aqilion and Merck partner to develop TAK1 protein inhibitors appeared first on Pharmaceutical Technology. Aqilion will handle the design and synthesis of the new small molecule TAK1 inhibitors.

Pharmacology 59

Pharmacology Sales Leads Medical 59

Pharmaceutical Technology

NOVEMBER 4, 2022

Reaction will also obtain lab facilities, equipment, staff, cell lines and expertise in toxicology, pharmacology, pathology and bio analytics from vivoPharm. This will further extend Reaction's industry-leading drug discovery service suite for customers in the biopharmaceutical sector.

Pharmacology 52

Pharmacology Leads Pharmaceutical 52

Rep-Lite

FEBRUARY 28, 2024

These certifications delve into specific areas of the healthcare industry, such as pharmaceuticals, medical devices, biotechnology, or healthcare regulations. Sales professionals gain a deeper understanding of complex topics like pharmacology, anatomy, physiology, disease pathology, and the latest advancements in medical technology.

Medical sales 52

Medical sales Medical Sales Ethics 52

European Pharmaceutical Review

AUGUST 23, 2022

PTSD is a potentially chronic condition that disrupts lives and can lead to or exacerbate existing health issues such as depression, anxiety, eating disorders, and suicidal thoughts. Many people have PTSD, but there [are] few effective pharmacologic treatments and limited drug development for PTSD,” commented Gradus.

Food and Drug Administration 78

Food and Drug Administration Pharmacology Prospecting Medical 78

European Pharmaceutical Review

MARCH 11, 2024

Reducing HIV treatment burden and stigma Decades of pharmaceutical advances and an array of treatment and prevention options mean that many people living with HIV can expect to live longer and fuller lives. Future innovation will be defined by ultra-long-acting options, self‑administration and, hopefully, concrete steps toward a cure.

Medicine 96

Medicine Pharmacology Healthcare Healthcare 96

pharmaphorum

DECEMBER 20, 2022

The condition is largely associated with obesity and an unhealthy diet and lifestyle, and is on the rise in industrialised nations, leading to estimates it could present a market opportunity worth tens of billions of dollars worldwide.

Pharmacology 52

Pharmacology Pharma Marketing Biopharma 52

European Pharmaceutical Review

MAY 2, 2023

Cancer remains a global threat with around 10 million people dying from the disease each year worldwide, making it the second leading cause of death. Central to this is embracing the power of strategic collaborations , through partnering with other pharmaceutical companies and academia. 1,2 In the EU, an estimated 2.7 2016;15(7):447.

Patients 104

Patients Medicine Marketing Medical 104

European Pharmaceutical Review

FEBRUARY 14, 2024

The development of drug products containing live anaerobic bacterial strains as the active pharmaceutical ingredient and where potency and shelf-life is typically associated with viable cell quantification, poses unique challenges when compared to both small and large molecule development therapeutics.

Food and Drug Administration 87

Food and Drug Administration Manufacturing Engineering Pharmacology 87

European Pharmaceutical Review

MARCH 6, 2024

The facility will also have capacity to conduct non-clinical pharmacology studies for detailed characterisation of its first-in-class development candidates, according to Ariceum. Internet] European Pharmaceutical Review, Issue 3 2023. 1 References Jaafar-Thiel. Meeting rising demands of a new radiotheranostic era. cited 2024Mar].

Pharmacology 98

Pharmacology Leads Pharmaceutical Patients 98

Rep-Lite

JUNE 28, 2023

Medical sales encompasses various sectors, including pharmaceuticals, medical devices, biotechnology, diagnostics, and healthcare IT. Some common roles include pharmaceutical sales representative medical device sales representative clinical specialist territory manager and account executive.

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Medical sales Medical Sales Medical sales reps 52

European Pharmaceutical Review

SEPTEMBER 29, 2022

Most ISRs were mild to moderate in severity and none lead to premature discontinuation from the study. There were no life threatening TEAEs, TEAEs leading to premature discontinuation of study, serious adverse events (SAEs) or deaths. PPD is an extremely common psychological condition affecting women after labour.

Pharmacology 100

Pharmacology Leads Patients Management 100

European Pharmaceutical Review

JULY 27, 2023

Cardiovascular diseases are the leading cause of death globally with over 18.5 Cardiovascular diseases are the leading cause of death globally with over 18.5 Meta‑analyses of these trials have shown that the therapy is safe and can lead to a reduction in incidences of death and recurrent myocardial infarction. to 1 percent).

Pharmacology 97

Pharmacology Manufacturing Leads Medicine 97

Pharmaceutical Technology

FEBRUARY 8, 2023

The recent town hall, titled “Clinical Development of Gene Therapy Products for Rare Diseases”, was meant to further that dialogue with those in pharmaceutical industry developing new gene therapies for underserved patient groups. GlobalData is the parent company of Pharmaceutical Technology.

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FDA Pharmacology Patients Pharmaceutical 105

pharmaphorum

JANUARY 16, 2023

Across swathes of primary care, pharmacological innovation has stalled; the last new antihypertensive class was introduced in 2007 and new antibiotics have trickled in at a dangerously slow pace. Alzheimer’s is currently the seventh-leading cause of death globally and growing fast.

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FDA Healthcare Healthcare Medicine 83

European Pharmaceutical Review

JANUARY 18, 2024

GlobalData’s Analyst covering Neurology and Ophthalmology, Thomas Parker, MPharmacol, predicted that Belsomra would lead the market by 2023. The post Market outlook to 2032: future trends across the seven major markets appeared first on European Pharmaceutical Review. million in sales by 2032.

Marketing 96

Marketing Sales Pharmacology Pharma 96

European Pharmaceutical Review

DECEMBER 11, 2023

Known linkers in the RNA field are used to bond together the two pharmacologically active molecular entities and can be applied to multiple oligonucleotide modalities. Research advances are also helping us learn more about how RNA is processed, potentially leading to new strategies to alter dysfunctional RNA. 2019 ;42:385-406.

Pharmacology 92

Pharmacology Safety Engineering Medical 92

Pharmaceutical Technology

FEBRUARY 13, 2023

However, there is a high level of attrition during the pharmaceutical research and development process, which is an indicator of the vast number of potential drug substances considered for progression. Therefore, it is vital to choose molecules for pharmaceutical development very carefully.

Food and Drug Administration 52

Food and Drug Administration Leads Pharmaceutical Pharmaceutical research 52

European Pharmaceutical Review

SEPTEMBER 22, 2023

Targeting toxic species of Abeta, such as multimers (with aducanumab and lecanemab) or pyroglutamate Abeta3-42 (with donanemab), induced significant removal of Abeta plaque load in the brains of Alzheimer’s patients, leading to the delay in cognitive decline. Treatment with the mAbs delayed cognitive decline by 2.6 months for lecanemab and 5.5

Food and Drug Administration 87

Food and Drug Administration Safety Patients Leads 87

Pharmaceutical Technology

NOVEMBER 3, 2022

Drug shortages have been a global problem for a decade and are increasingly affecting the EU, said an EMA spokesperson to Pharmaceutical Technology in an email. But these substitutions do not come without complications, as these drugs can vary in their pharmacologic properties, states Page.

Medicine 111

Medicine Manufacturing Pharmacology Healthcare 111

Quantified

JUNE 28, 2022

The reality is that leading companies are looking for ways to drive impact that go beyond optimizing reach and frequency. To do this, they will not only need new knowledge but a substantially better ability to engage, connect and influence the HCP, leading to more meaningful interactions and increased conversion.

Sales 52

Sales Pharma Training Management 52

Map My Customers

MARCH 31, 2022

Pharmaceutical sales representatives will be the face of the company for drug and treatment manufacturers. As a pharmaceutical sales rep, there are appointments and meetings with doctors and professionals that need to stay up to date with the latest pharmacology treatment options for their patients.

Medical sales reps 52

Medical sales reps Medical sales Medical Sales 52

Pharmaceutical Technology

AUGUST 8, 2022

The digital pill, now marketed by Otsuka Pharmaceuticals, is forecasted to make $27 million in sales in 2022, as per GlobalData. GlobalData is the parent company of Pharmaceutical Technology. But the pharmacology to quantify adherence also depends on race, gender, weight, and other factors.

Food and Drug Administration 122

Food and Drug Administration FDA Medicine Patients 122

Pharmaceutical Technology

FEBRUARY 17, 2023

However, Amgen and other pharmaceutical companies have been criticised when they opted to choose the drug’s dosage based on the MTD model, which is commonly used in dose-finding trials. However, this would also lead to a revaluation of Amgen’s financial predictions for the drug, as a lower recommended drug dosage may generate less revenue.

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FDA Side effects Pharmacology Patients 115

Pharmaceutical Technology

JUNE 15, 2023

Entering into select, high-value collaborations allows us to efficiently deploy our platform together with leading companies while we continue to build out our own pipeline of innovative and impactful medicines.” Early R&D projects coverage on Pharmaceutical Technology is supported by Mimotopes.

Pharmacology 52

Pharmacology Medicine Sales Leads 52