European Pharmaceutical Review

NOVEMBER 24, 2023

Amgen’s new immunotherapeutic agent Tarlatamab has been shown in a Phase II trial to provide sustained anti-tumour activity in 40 percent of the small cell lung cancer patients. The international DeLLphi-301study was investigated as a new anti-cancer treatment option for patients previously considered to be beyond treatment.

Side effects 107

Side effects Patients Medicine Leads 107

European Pharmaceutical Review

OCTOBER 9, 2023

A new drug, part of a class of chemicals called potassium-channel openers, has demonstrated potential in offering relief to patients with focal epilepsy. Comparatively, patients given a placebo had on average 18 percent fewer seizures during the treatment phase of the trial, which lasted eight weeks.

Side effects 95

Side effects Recruitment Safety Medicine 95

European Pharmaceutical Review

OCTOBER 21, 2022

Clinical trial results presented at the US IDWeek conference, revealed a three-dose series of the HEPLISAV-B vaccine prevents hepatitis B virus (HBV) in HIV patients not previously vaccinated against or infected with the virus. A breakdown of the data showed: HbsAb levels were greater than 1000mIU/ml in 88 percent of patients.

Patients 76

Patients Food and Drug Administration Side effects Food 76

Rep-Lite

DECEMBER 7, 2023

Getting into pharmaceutical sales and selling pharmaceutical products may require patience and persistence, but for individuals with the right qualifications and a passion for the field, it can be a rewarding and financially lucrative career. What is Pharmaceutical Sales? Why Pursue a Career in Pharmaceutical Sales?

Pharmaceutical Sales 52

Pharmaceutical Sales Pharmaceutical Sales Interpersonal Skills 52

European Pharmaceutical Review

MARCH 9, 2023

A pilot study has demonstrated that a nasal version of the drug Foralumab, an anti-CD3 monoclonal antibody suppressed the inflammatory T cell response and decreased lung inflammation in patients with COVID-19. Foralumab’s immune modulating response In 2020, Moreira researched how Foralumab modulates the immune response to reduce inflammation.

Side effects 145

Side effects Patients Leads Medical 145

European Pharmaceutical Review

DECEMBER 22, 2023

The deal includes Karuna’s lead asset KarXT (xanomeline-trospium), a potential first-in-class treatment for schizophrenia. It has demonstrated improvements in cognition and is not associated with common side effects of currently approved treatments like weight gain.

Food and Drug Administration 95

Food and Drug Administration Side effects Safety Food 95

European Pharmaceutical Review

NOVEMBER 9, 2023

Following her presentation on age-related disease at BioFuture 2023, Executive Vice President of Drug Development for MyMD Pharmaceuticals ® , Jenna Brager, shares with EPR why the company’s next-generation tumour necrosis factor (TNF)-alpha inhibitor has potential in inflammatory and autoimmune disorders.

Food and Drug Administration 106

Food and Drug Administration Side effects Pharmaceutical Leads 106

European Pharmaceutical Review

JULY 5, 2022

The availability of oral chemotherapy treatments would provide stomach cancer patients with the option of more efficacious drugs with improved tolerability in a more convenient dosage format” The poor clinical outcomes of stomach cancer make it a key target for drug development. New hope for stomach cancer patients.

Patients 85

Patients Food and Drug Administration Side effects Safety 85

European Pharmaceutical Review

MARCH 30, 2023

Intrathecal (IT) (directly into the spinal fluid) and intravenous (IV) nivolumab (anti-PD-1) immunotherapy was found to be safe and improved survival in a subset of melanoma patients with leptomeningeal disease (LMD). Results of the immunotherapy study Across 25 patients, the median overall survival (OS) was 4.9

Side effects 81

Side effects Patients Medicine Leads 81

European Pharmaceutical Review

MARCH 8, 2023

If the orally-delivered drug is confirmed have similar in safety and efficiency as the injectable forms, researchers stated that a PCSK9 inhibitor in a pill form could lower costs, increase convenience and expand patient access to the treatment. This is a highly effective compound that was well tolerated,” stated Dr Christie M.

Side effects 88

Side effects Safety Medicine Patients 88

World of DTC Marketing

FEBRUARY 22, 2021

Jazz Pharmaceuticals has introduced a new prescription medication for patients with sleep apnea/narcolepsy that “helped adults get up to 9 hours of improved wakefulness in clinical studies at 12 weeks” and they’re using a flying pig on their DTC. billion by 2026. This DTC is an embaressment.

Pharma 181

Pharma Doctors Side effects Prescription 181

European Pharmaceutical Review

NOVEMBER 3, 2023

The Medicines and Healthcare products Regulatory Agency (MHRA) has authorised Pfizer’s Litfulo (ritlecitinib) for treatment for severe alopecia areata in patients 12 years and older. The post MHRA authorises alopecia treatment appeared first on European Pharmaceutical Review. Results from this pivotal study showed that 13.4

Food and Drug Administration 87

Food and Drug Administration Side effects Medicine Food 87

European Pharmaceutical Review

APRIL 12, 2023

Patients treated with blood pressure-lowering drugs can experience greater improvements from changing medication compared to doubling the dose of their current medication, a study from Sweden has shown. Four different blood pressure-lowering drugs were tested in 280 Swedish patients over one year.

Side effects 91

Side effects Medical Patients Leads 91

European Pharmaceutical Review

MAY 31, 2023

coli which can cause life-threatening bloodstream infections in vulnerable haematological cancer patients. It has potential to prevent these infections in over 35,000 cancer patients annually across Europe and the US, according to the researchers. coli infections in high-risk cancer patients.

Side effects 86

Side effects Patients Leads Pharmaceutical 86

pharmaphorum

JULY 14, 2022

In a statement , the health technology assessment (HTA) organisation said that the two drugs were backed after an agreement with the two developers on pricing that will make them an option for around 3,450 NHS patients. NICE estimates that around 2,800 people are eligible for treatment with Piqray plus fulvestrant.

Side effects 95

Side effects Medicine Patients Government 95

Pharmaceutical Technology

NOVEMBER 14, 2022

In September, a group from Friedrich Alexander University Erlangen-Nuremberg reported that five patients with lupus achieved remission after an infusion of autologous chimeric antigen receptor (CAR)-T cells led to a deep depletion of B cells. All five patients achieved remission after three months.

Side effects 144

Side effects Patients Manufacturing Safety 144

European Pharmaceutical Review

SEPTEMBER 20, 2022

This interchangeability refers to the fact that a reference medicine can be substituted by a biosimilar, without risk, side effects or outcomes different to the original drug. Clinically, it is common practice for doctors to rotate patients between different biologics. New regulatory guidance could lead to UK biosimilar boom.

Medicine 91

Medicine Side effects Safety Doctors 91

PM360

MAY 25, 2023

ChatGPT is poised to revolutionize the pharmaceutical industry by providing innovative communication and marketing strategies. With AI-powered chatbots and services, patients can access the information they need more efficiently. Integrating AI tools with communication between parties can lead to better results when used correctly.

Marketing 98

Marketing Pharma Healthcare Provider Healthcare 98

Pharmaceutical Technology

JUNE 1, 2023

It will also help predict any potential side effects of these medicines. This could prove to be beneficial for patients and the health system by providing increased access to advanced, cost-effective drugs. Cell & Gene Therapy coverage on Pharmaceutical Technology is supported by Cytiva.

Medicine 97

Medicine Side effects Manufacturing Leads 97

European Pharmaceutical Review

JANUARY 30, 2023

Ultimately, this can lead to a progressive decrease in mobility and other severe impairments. This medicine was intended for the treatment of severe malaria caused by the parasite Plasmodium falciparum in patients in the EU. These side effects include cardiovascular conditions, blood clots, cancer and serious infections.

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Side effects Medicine Marketing Patients 75

Silver Line CRM

NOVEMBER 11, 2020

Reading time: 7 minutes As we all look to 2021, what are the pharmaceutical industry trends to build into your life sciences marketing strategy? Pharmaceutical, biotech, and life sciences companies bring life-changing medicines to a highly regulated market. 2021 pharmaceutical industry trends — and how you can implement them.

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Marketing Pharmaceutical Side effects Insurance 52

pharmaphorum

SEPTEMBER 16, 2022

Atopic dermatitis (AD) is a highly prevalent chronic dermatological disease, with symptoms which include itching, dry skin, severe pain, and inflammation – all of which create considerable stress in the daily lives of patients and often negatively affect their day-to-day and long-term well-being. However, side effects do happen.

Management 85

Management Side effects Patients Safety 85

European Pharmaceutical Review

DECEMBER 21, 2022

Already, the course of their illness is so much better than with the typical treatment,” stated Dr Mort Cowan, UCSF paediatrics professor and the trial’s lead investigator. Artemis-SCID patients usually respond more poorly to standard bone marrow transplants. Having patients in the trial achieve full T-cell immunity is outstanding.

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Side effects Patients Leads Medicine 103

PM360

MAY 25, 2023

Carl Marci, Chief Psychiatrist and Managing Director of Mental Health and Neuroscience at OM1 , about how the company is using its Mental Health and Neuroscience Real-World Data Network to help improve personalized treatment for mental health patients and increase awareness about issues related to mental health disorders.

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Side effects Medical Patients Networking 95

Pharmaceutical Technology

MARCH 7, 2023

Clene has presented updated trial results for its Visionary MS Phase II clinical trial for its lead pipeline candidate, CNM-Au8. The trial is investigating CNM-Au8 as a treatment for patients with relapsing forms of multiple sclerosis (MS) with chronic optic neuropathy.

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Side effects Patients Leads Safety 100

European Pharmaceutical Review

MARCH 10, 2023

Ocular suspensions and emulsions can deliver hydrophobic drugs, but may lead to blurred vision. However, high viscous eye drops are irritating for many patients, do not provide an accurate dose and result in blurred vision. The post Enhancing bioavailability in ocular drug delivery appeared first on European Pharmaceutical Review.

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Side effects Management Leads Safety 77

Pharmaceutical Technology

APRIL 24, 2023

While 80% of the world’s population practices some form of traditional medicine, according to the World Health Organization (WHO), the practice is regularly discredited due to a lack of scientific support and regulation as well as evidence of negative side effects with certain medicines.

Medicine 105

Medicine Side effects Healthcare Healthcare 105

European Pharmaceutical Review

MARCH 14, 2024

This month, new data from Novo Nordisk has revealed that semaglutide could become the first GLP-1 treatment option for patients with type 2 diabetes and chronic kidney disease (CKD). This leads to the formation of immune complexes that deposit in the glomerulus and result in haematuria, proteinuria, and decline in kidney function.

Food and Drug Administration 95

Food and Drug Administration Side effects Leads Patients 95

European Pharmaceutical Review

OCTOBER 7, 2022

Slow-release formulations were a popular choice for manufacturers, as these varieties reduce the traditional dosage frequency for patients, who only need to take these medications say, once a week. This is especially beneficial as a way of decreasing potential side effects.

Manufacturing 85

Manufacturing Marketing Side effects Transportation 85

European Pharmaceutical Review

MARCH 14, 2024

This month, new data from Novo Nordisk has revealed that semaglutide could become the first GLP-1 treatment option for patients with type 2 diabetes and chronic kidney disease (CKD). This leads to the formation of immune complexes that deposit in the glomerulus and result in haematuria, proteinuria, and decline in kidney function.

Food and Drug Administration 94

Food and Drug Administration Side effects Leads Patients 94

Pharmaceutical Technology

APRIL 14, 2023

Madrigal Pharmaceuticals’ resmetirom for nonalcoholic steohepatitis (NASH) could be fairly priced at a higher range than Intercept Pharmaceuticals’ obeticholic acid, based on a revised evidence report published by the Institute for Clinical and Economic Review (ICER). Caveats surrounding side effects for obeticholic acid remain.

Side effects 52

Side effects Patients Leads Pharmaceutical 52

European Pharmaceutical Review

JANUARY 11, 2024

The current medications (opioid and non-opioid) often force the patients to make an unfortunate choice between efficacy and debilitating side effects, leading to a cycling through multiple different therapies and suboptimal treatment response. The present unmet needs within chronic pain are not met with opioid therapies.

Medicine 80

Medicine Pharmacology Management Side effects 80

European Pharmaceutical Review

JANUARY 25, 2024

Within the EU, patient information leaflets (PILs) are not merely a regulatory requirement but a cornerstone of patient safety. They detail the medication’s intended use, proper administration, potential side effects and precautions. percent as EU average with some Member States as high as 25 percent).

Healthcare 84

Healthcare Healthcare Electronics Safety 84

Pharmaceutical Technology

JUNE 16, 2023

Belgium-headquartered ANeuroTech is participating in a Series B round, which will raise up to $150m to power the pivotal programme of its lead candidate ANT01 for use as an adjunctive treatment for major depressive disorder (MDD). Due to this, adjunctive treatments are used as part of a patient’s treatment regimen.

Food and Drug Administration 52

Food and Drug Administration Side effects Safety Recruitment 52

Pharmaceutical Technology

AUGUST 26, 2022

The Bill and Melinda Gates Medical Research Institute (Gates MRI) has previously teamed up with major pharmaceutical companies to advance TB research, but the development of these new drug regimens is a new step in their collaborative efforts. Each trial will recruit approximately 500 patients. Challenges of current TB treatment.

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Side effects Pharmaceutical Patients Recruitment 98

Pharmaceutical Technology

JUNE 15, 2023

But before pharmaceutical companies can go to market with a breakthrough drug, they need to ensure safety and efficacy through clinical trials. Clinical trials are divided into phases evaluating drug safety, side effects and effectiveness from increasingly larger pools of candidates and patients.

Food and Drug Administration 52

Food and Drug Administration Side effects Recruitment Safety 52

European Pharmaceutical Review

MARCH 24, 2023

In NASH, excess fat in the liver can lead to progressive disease, including inflammation, liver cell injury and fibrosis, which are associated with increased risk for cardiovascular disease and liver morbidity and mortality. Pegozafermin also has a favourable safety and tolerability profile, with few gastrointestinal (GI) side effects.

Medical 85

Medical Side effects Safety Pharmaceutical 85