Mon.Oct 30, 2023

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UPDATED: Pfizer plans to shutter New Jersey site, discloses layoffs amid $3.5B cost-cutting drive

Fierce Pharma

Editor's note: This story has been updated with a comment from Pfizer. An earlier version of the story stated that nearly 800 jobs would be affected. | After plunging COVID revenues prompted Pfizer to embark on a cost-cutting crusade, more details about the company's savings efforts are coming into focus.

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Health Exec: 97% of Healthcare Data Isn’t Used

MedCity News

The vast majority of healthcare data isn’t used because it’s difficult to work with, according to Beth Andrews, chief digital health officer of life sciences and healthcare at Dell Technologies. Andrews made these comments during a session at the MedCity News INVEST Digital Health conference.

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Sarepta's Elevidys fails on primary endpoint, but executives see path to wider DMD approval anyway

Fierce Pharma

After Sarepta overcame several regulatory hurdles to finally win | After Sarepta overcame several regulatory hurdles to finally win FDA approval for its DMD gene therapy Elevidys, the company now faces the prospect of more FDA scrutiny because a pivotal study on the drug has failed on the primary endpoint.

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What Excites Health Execs About the Evolution of Employee Benefits

MedCity News

Value-based care and data are areas to be excited about in the employee benefits space, executives shared during a panel discussion at the MedCity News INVEST Digital Health conference.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Eli Lilly, Redwire head to space to explore next frontier of drug development

Fierce Pharma

After Bristol Myers Squibb’s space odyssey earlier this year, another pharmaceutical major is pushing drug development to the fringes of Earth’s gravitational pull. | Eli Lilly is entering the orbit of Redwire Corporation to test the latter company's in-space drug manufacturing platform. The technology will be sent to the International Space Station aboard a SpaceX mission set to launch sometime after Nov. 5.

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Improving Hypertension Care for Underserved Populations with Remote Patient Monitoring

MedCity News

Given the impact that RPM can have in addressing chronic conditions like hypertension, there is a distinct need for more funding to ensure all people have access to proven, digital health interventions. Regulations must be revamped so FQHCs, RHCs and CHCs are able to bill for RPM, much like other hospitals and health centers.

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Multilocation Healthcare Marketing: Minimum Daily Requirements

Healthcare Success

Do you want to compete in each of your local markets? Do you want to position your healthcare products and services where your target audience actively seeks them? If so, you need a custom digital marketing strategy and budget for each location. We like to call this budget the “minimum daily requirement.” Why is this so important? Unless you have a solid local strategy, your business will not show up online where and when it matters most.

Marketing 118
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Amgen, Regeneron and AbbVie join Lilly and Novo Nordisk in posting largest Q3 market-cap gains: report

Fierce Pharma

As sales of their GLP-1 diabetes and obesity drugs have surged, Eli Lilly and Novo Nordisk have become the most valuable biopharma companies in the United States and Europe, respectively. That didn | It was no surprise that GLP-1 drugmakers Eli Lilly and Novo Nordisk saw market-cap gains of 16.1% and 13.9% in the third quarter. But much less expected were the market-cap rallies of Amgen (22.1%), Regeneron (14.9%) and AbbVie (13.1%), according to figures compiled by GlobalData.

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How the Millions of Americans Losing Medicaid Can Stay Insured

MedCity News

In all, up to 18 million Americans could lose Medicaid coverage through June 2024. Fortunately, the vast majority of these folks have a number of options for obtaining affordable coverage. They just have to know where to look.

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Bluebird inks deal to sell its next FDA priority review voucher to Novartis for $103M

Fierce Pharma

As an FDA decision draws closer on bluebird bio’s sickle cell disease gene therapy, the company has lined up a potential sale of a priority review voucher (PRV). | The company entered an advance agreement for a priority review voucher ahead of the FDA's decision on the sickle cell disease gene therapy prospect. Bluebird expects the FDA to decide on its drug by December 20.

FDA 223
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Novartis Drug From $3.2B Deal Succeeds in Phase 3, 2024 FDA Filing Is Planned

MedCity News

Novartis drug candidate atrasentan met the main goal of a pivotal study in the chronic kidney disease IgA nepropathy. It’s one of two drugs added via the multi-billion dollar acquisition of Chinook Therapeutics; together with a homegrown therapeutic candidate, they give Novartis three different approaches to treat the rare disorder.

FDA 112
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Metformin helps manage weight gain side effect of SGAs

European Pharmaceutical Review

A large-scale study led by researchers at the University of Cincinnati and New York’s largest health care provider, Northwell Health, suggests that metformin can help prevent or reduce weight gain in youth taking second-generation antipsychotics (SGAs) to treat bipolar disorder. SGAs used to treat bipolar disorder are often effective at helping young patients’ mental health improve but can have significant side effects including elevated blood pressure and glucose, increased appetite, as w

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Merck KGaA Puts Up €160M for Drug to Rival DNA Damage Cancer Meds From AstraZeneca, Gilead

MedCity News

A Hengrui drug that interferes with a cancer cell’s DNA damage response is heading to Merck KGaA for €160 million up front and up to €1.4 billion tied to milestones. The deal also gives the German company an option to license a Hengrui antibody drug conjugate.

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HDA Launches New Communications Initiative

Pharmaceutical Commerce

Effort displays the diverse perspectives, skills, and people involved with the healthcare supply chain, as industry aims to continue to push DE&I forward.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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BioLabs Pegasus Park Cultivates Life Science Ecosystem [Sponsored]

MedCity News

Gabby Everett, the site director for BioLabs Pegasus Park, offered a tour of the space and shared some examples of why early-stage life science companies should choose North Texas.

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Are we globally prepared for the next pandemic?

European Pharmaceutical Review

Echoes of the global health challenges we faced during the COVID-19 pandemic still linger as new variants emerge and COVID continues to make headlines. A question that continues to sit in the back of many people’s minds is what happens if there is another outbreak or global pandemic? Are we preparing and how ready are we for the next one? Vaccitech’s Chief Business Officer, Graham Griffiths, discusses key learnings in drug and vaccine development , the challenges of preparing for the unknown, an

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Future-Proofing Healthcare Delivery [Sponsored]

MedCity News

In a fireside chat at INVEST Digital Health in Dallas, Polsinelli Healthcare M&A Co-chair Jonathan Henderson and Jim Walton, President of JWalton LLC discussed the healthcare preferences of different generations and how they will impact caregiving.

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Gene therapy for rare muscular dystrophy presents preliminary promise

European Pharmaceutical Review

Atamyo Therapeutics ’ one-time gene therapy for fukutin-related protein (FKRP) limb-girdle muscular dystrophy Type 2I/R9 (LGMD2I/R9) has enabled clinical trial patients to experience symptom relief, as well as a correction of centronucleation. LGMD2I/R9 is a rare genetic disease caused by mutations in the gene that produces fukutin-related protein (FKRP).

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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What’s next for COVID dark horse Novavax?

PharmaVoice

Novavax scored a new COVID vaccine go-ahead for the 2023-24 season, but is it the boost the company needs?

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FDA warns of infection risks from over-the-counter eye drops 

Pharmaceutical Technology

The US FDA has issued a warning against the use of 26 over-the-counter eye drop products due to potential eye infection risks.

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Five top tips for advancing DEI in research environments

Clarivate

Academic experts share how they’re shifting the cultural dial in favor of diversity, equity and inclusion There is now widespread acknowledgement that diversity strengthens research environments, creating a fairer, more equitable culture in which people from all backgrounds can thrive. But the growing attention paid to diversity, equity and inclusion (DEI or EDI) has not yet translated into the scale or pace of change needed to unlock research careers for many people from groups under-represente

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EMA dismisses thyroid cancer link with anti-obesity GLP-1 receptor agonists

Pharmaceutical Technology

An EMA safety panel concluded that available evidence does not prove that GLP-1 receptor agonists cause thyroid cancer.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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NIHR data reveals commercial study set up times reduce by a third

PharmaTimes

Over 600 commercial studies have been reviewed in the past 12 months - News - PharmaTimes

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AI skills can increase worker salary as much as 40%, says study

Pharmaceutical Technology

A new study published by the Oxford Internet Institute has found that AI skills and knowledge can increase a worker’s salary as much as 40%.

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NHS roaming trucks identify over 2000 people at risk of liver cancer

PharmaTimes

The NHS has been visiting at-risk communities to detect liver cancer earlier - News - PharmaTimes

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Implementing Sustainable Business Practices

Pharmaceutical Commerce

Raphael Chin Fo Sieeuw offers his insight on how to address the sector’s most prominent issues, including how to limit the industry’s carbon footprint.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Coherus and Junshi’s PD-1 inhibitor approved for nasopharyngeal carcinoma

Pharmaceutical Technology

A Loqtorzi/chemotherapy combination has been approved as a first-line therapy in adults with metastatic or recurrent locally advanced NPC.

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Atrasentan data backs up Novartis’ $3.5bn Chinook deal

pharmaphorum

Atrasentan data backs up Novartis’ $3.5bn Chinook deal Phil.

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10 Best Sales Tracking Apps

Spotio

How many leads are in your sales pipeline right now? Which sales activities produced these leads? Do any of them move prospects through the funnel more consistently than others? As a sales manager, you need to know the answer to these questions. If you don’t, you’ll never build an effective sales strategy that achieves real results for your organization.

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Navigating the Digital Landscape: SEO Best Practices for Pharma Websites

Pharma Marketing Network

As digital technology continues to rapidly evolve, companies in the pharmaceutical industry must remain competitive by adapting to the changing landscape. Search engine optimization (SEO) is an essential component of any successful digital marketing strategy, and it is crucial for pharma websites to understand and apply SEO best practices. This article will cover the basics of navigating the digital landscape, SEO strategies for pharma websites, optimizing content for SEO, and measuring SEO succ

Pharma 52
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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.