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Japan's Ono pays $2.4B for Qinlock-maker Deciphera as biotech readies another approval run

Fierce Pharma

The price tag includes both the approved cancer drug Qinlock and another Deciphera candidate heading to the FDA’s desk in the coming months.

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Lutris wins FDA orphan drug tag for EGFR inhibitor-induced rash candidate

Pharmaceutical Technology

LUT014 is being investigated in an ongoing Phase II trial as a first-line treatment for EGFR inhibitor-induced acneiform rash, for which there is no approved drug.

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CEPI provides $30m to advance novel coronavirus vaccine

European Pharmaceutical Review

Many current COVID-19 vaccine candidates work by presenting fragments of the SARS-CoV?2 These coronavirus RBDs are attached to a nanoparticle by protein tags, enabling the structure to display fragments from multiple viruses on a single nanoparticle. . How the novel coronavirus vaccine works. 2 is the virus that causes COVID-19.).

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Axsome bounces back as FDA clears depression drug

pharmaphorum

There’s no word yet on its pricing, but for comparison Spravato was launched with an annual price tag of around $32,400, which the Institute for Clinical and Economic Review (ICER) concluded was around 25% to 52% too high to be cost effective. Following after is AXS-12 (reboxetine) for narcolepsy, which could be filed in 2023.

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The True Cost of a Bad Sales Hire and How to Avoid It

CloserIQ

With that kind of a price tag, avoiding a bad sales hire is imperative. Follow these best practices to help you prevent this from happening: 1) Create a profile of the ideal job candidate for each position. Compare all job candidates against the profile. 3) Beware of candidates who have hopped between jobs extensively.

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Actualising the power of antibody-drug conjugates as cancer therapeutics

European Pharmaceutical Review

tag ® , inspired by the unique features of microtubule biology and perfectly suited for DAR 2 and DAR 4 ADCs. This is based on ethynylphosphonamidates that prevent premature cleavage of the linker payload during circulation and increasing hydrophilicity of the ADC while keeping the distance between antibody and payload to a minimum.

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bluebird unveils $2.8m price for gene therapy Zynteglo on FDA approval

pharmaphorum

million price tag attached to the therapy when it was first made available in Europe, and is also well above the proposed $2.1 Zynteglo is a customised, one-time treatment created using a patient’s own bone marrow stem cells hat are genetically modified to produce functional beta-globin, which is mutated in the disease.

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