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FDA approves Ipsen’s Bylvay for cholestatic pruritus due to ALGS

Pharmaceutical Technology

Bylvay is a once-a-day, non-systemic ileal bile acid transport inhibitor (IBATi) that acts locally in the small intestine and has minimal systemic exposure. The findings showed that odevixibat provided statistically significant and clinically meaningful sustained improvement in pruritis, beginning soon after treatment commenced.

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Delivery systems for biologics

European Pharmaceutical Review

Therefore, biologics identification and characterisation poses unparalleled challenges, as does their manufacturing processes and routes of administration while maintaining patient safety and clinical efficacy. Notably, LNPs facilitate the transportation of large payloads, have limited immunogenicity, and allow for scalable manufacturing.

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The Caregiver Vertical: How Pharma Engages

Pharma Marketing Network

Members of a multidisciplinary care team may include physicians, nurses, pharmacists, radiologists, dieticians…the list goes on. 80% provide transportation 1. Caregiver observations of the patient experience over the progression of the disease may inform the safety and efficacy of a particular therapeutic.

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T2D market growth driven by novel GLP-1RAs and once-weekly basal insulin therapies

Pharmaceutical Technology

The erosion of Januvia is due to patent expiry in that had been expected in 2022 and physicians’ preference for sodium-glucose linked transporter-2 inhibitor (SGLT-2I) therapies such as Farxiga (dapagliflozin) and Jardiance (empagliflozin) due to their ability to improve glycemic control and address cardiorenal comorbidities.

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Merck, Bristol-Myers Squibb, and Clarify discuss diversity in clinical trials

Clarify Health

Additionally, RWE that delivers comprehensive social determinants of health insights encompassing gender, race, ethnicity, income level, transportation access, housing stability, education level, and health literacy can be used to assess diversity criteria among eligible patients.

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How one pharma “family business” places patients first

pharmaphorum

There are many challenges in the development of therapies for rare diseases due to several unique factors, including small target patient populations, lack of long-term safety and efficacy data or natural history data, and often complex administration, dosing, and patient monitoring requirements,” Chiesi says.

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From Europe To The U.S.: A Medtech Executive’s Career Chronicle With Fred Colen

Evolve Your Success

The patient is in control of giving the basic command, but the whole system is set up by the physician in terms of optimizing all the specific individual interactions. You also have to keep reaching out to the people in the field that is your colleagues and the physicians as well as financial people out there. Take us back.