European Pharmaceutical Review

JULY 13, 2023

While this is essential in the interrogation of novel compounds for which we know very little about their efficacy and safety, it is also true that some biomedical research is highly wasteful. An observational study of safety and clinical outcome measures across patient groups in the United Kingdom Medical Cannabis Registry.

Medical 86

Medical Food and Drug Administration Pharmacology Medicine 86

Contrarian Sales Techniques

FEBRUARY 25, 2023

During my pharmacology class, I learned that there are no safe drugs, only safe patients. Clinical studies play an essential role in determining the safety and efficacy of new drugs before they can be approved for the public. This includes potential side effects or adverse reactions to medications.

Side effects 52

Side effects Medical sales reps Insurance Pharmacology 52

European Pharmaceutical Review

JULY 19, 2023

The data “are compelling, particularly the significant improvements observed in both depressive and anhedonic symptoms,” stated Dr Roger S McIntyre, FRCPC, Professor of psychiatry and pharmacology, University of Toronto and Executive Director of the Brain and Cognition Discovery Foundation in Toronto, Canada.

Pharmacology 94

Pharmacology Patients Safety Medicine 94

PM360

NOVEMBER 29, 2022

Drug labels hold value for life sciences companies because they are rich, extensive documents that can be used across labeling, regulatory, safety, and medical affairs. Typically, a drug label refers to any information provided with prescription drugs, as requested by regulators such as the U.S.

Food and Drug Administration 98

Food and Drug Administration Competition Safety Pharmacology 98

Pharmaceutical Technology

SEPTEMBER 14, 2022

Victoza, Copaxone, Lupron, Zoladex, Sandostatin, and Somatuline are some of the popularly marketed peptide API therapeutic drugs while more than 600 peptide-based pharmacological leads are being investigated worldwide, across various phases of development.

Leads 52

Leads Marketing Pharmacology Retail 52

pharmaphorum

SEPTEMBER 9, 2022

Prior to the launch of those drugs, pharmacological therapy for obesity was something of a backwater, constrained by tolerability and safety issues for older, generic drugs, and lacklustre take-up of newer therapies with limited efficacy. Novo Nordisk recently predicted its obesity sales could reach $3.7 billion in 2025.

Pharmacology 95

Pharmacology Patients Management Consulting 95

Pharmaceutical Technology

AUGUST 16, 2022

Recently, Q32 concluded a Phase I clinical trial to evaluate the pharmacokinetics, pharmacodynamics and safety of ADX-914, which showed a pharmacological effect on T cells in healthy subjects. antibody, ADX-914 re-regulates adaptive immune function by hindering IL-7 and TSLP-facilitated signalling.

Food and Drug Administration 52

Food and Drug Administration Pharmacology Food Safety 52

Pharmaceutical Representative Training

JANUARY 11, 2021

Next, pharma reps need to have a strong foundation in basic science and pharmacology. Pharmacology is the science of medications and the role they play in the body. A great way to distinguish yourself from other candidates is to complete the Pharmaceutical Representative Certification (PRC) program.

Pharmaceutical Sales 52

Pharmaceutical Sales Pharma sales reps Pharma sales representatives Pharma sales representative 52

pharmaphorum

JANUARY 17, 2023

Angion chalked up a series of trial failures for its hepatocyte growth factor (HGF) mimetic ANG-3777 over the last couple of years, and turned its attention to tyrosine kinase receptor inhibitor ANG-3070 in kidney diseases and fibrotic disorders, before abandoning the drug due to safety concerns in the middle of 2022.

Pharmacology 71

Pharmacology Engineering Consulting Leads 71

pharmaphorum

DECEMBER 22, 2022

Pfizer reckons the pharmacology of etrasimod – including its engagement with S1P 1, 4 and 5 receptor subtypes – differentiates the drug from its rival, which binds mainly to subtypes 1 and 5. “We believe that etrasimod, if approved, has the potential to be a best-in-class, first-line advanced therapy.”

Pharmacology 52

Pharmacology Safety Patients Marketing 52

Legacy MEDSearch

DECEMBER 12, 2022

” Clinical studies have shown Nerivio to be as effective as standard of care pharmacological options for acute migraine treatment. Theranica recently published topline results of a pivotal trial demonstrating the efficacy and safety of Nerivio® also for the preventive treatment of migraine, currently under FDA review.

Side effects 98

Side effects Insurance FDA Pharmacology 98

Legacy MEDSearch

AUGUST 25, 2022

The primary safety endpoint is a performance goal for device and procedure related adverse events at 30 days. The FDA-approved randomized IDE trial has been designed to validate the safety and effectiveness of PiCSO.” Major adverse cardiac events and heart failure endpoints will be captured acutely and for up to 3 years.

Medical 52

Medical FDA Recruitment Pharmacology 52

pharmaphorum

DECEMBER 20, 2022

That’s impressive, as it has proved exceedingly difficult for pharmacological therapies to show an impact on fibrosis in prior studies. Similarly, a one-stage or greater improvement in liver fibrosis was seen in 24% and 26% of the resmetirom groups, respectively, versus 14% of patients taking placebo.

Pharmacology 52

Pharmacology Pharma Marketing Biopharma 52

European Pharmaceutical Review

MARCH 11, 2024

With therapeutic expertise in HIV, hepatology and rare diseases, Sherene has additional expertise in clinical pharmacology and drug safety. Sherene has worked in the healthcare sector for more than 20 years, including in several leadership roles at GSK.

Medicine 91

Medicine Pharmacology Healthcare Healthcare 91

European Pharmaceutical Review

MAY 2, 2023

By collaborating with several stakeholders and authorities, multiple stages of development can take place concurrently to speed up R&D without compromising safety protocols. The COVID-19 blueprint has shown a way forward. Previously, he spent more than 10 years at Roche in multiple positions within medical affairs.

Patients 100

Patients Medicine Marketing Medical 100

European Pharmaceutical Review

DECEMBER 11, 2023

mAbs have well-established safety profiles, high specificity and affinity and long half-lives – they have been used in drug development for more than 30 years. Known linkers in the RNA field are used to bond together the two pharmacologically active molecular entities and can be applied to multiple oligonucleotide modalities.

Pharmacology 84

Pharmacology Safety Engineering Medical 84

European Pharmaceutical Review

JULY 27, 2023

Pharmacological therapies mainly address symptoms and unfortunately a significant number of patients do not respond adequately, progressing to congestive heart failure and eventually needing a heart transplant. Despite these trials varying in design, they confirmed the feasibility and safety of the procedure. Frontiers in Pharmacology.

Pharmacology 92

Pharmacology Manufacturing Leads Medicine 92

European Pharmaceutical Review

SEPTEMBER 22, 2023

7 It is currently being evaluated in a Phase Ib/IIa clinical study, demonstrating to date a good safety profile. While favourable safety has been reported up to the Phase II, the relevance of targeting the C-terminal portion of Abeta still needs to be confirmed.

Food and Drug Administration 78

Food and Drug Administration Safety Patients Leads 78

Pharmaceutical Technology

FEBRUARY 8, 2023

Still, Blank suggested that companies enroll the patient population that is most likely to benefit, because early phase studies contain the most safety risks. Blank acknowledged that in many cases, an exclusively paediatric patient population could lead to difficulties with drawing consent for early phase trials.

FDA 105

FDA Pharmacology Patients Pharmaceutical 105

Pharmaceutical Technology

FEBRUARY 13, 2023

As well as presenting an acceptable PK profile and demonstrating in-vivo efficacy, it becomes important to show that the candidate drug has a good safety pharmacology margin with an acceptable drug-drug interaction (DDI) profile.

Food and Drug Administration 52

Food and Drug Administration Leads Pharmaceutical Pharmaceutical research 52

Medgadget

MAY 2, 2023

While for other patients the possible adverse side effects from medication may prevent them from finding pharmacological therapies effective. During this time, two additional studies ended successfully and were published, further validating the clinical safety and effectiveness.

Side effects 87

Side effects Prescription Healthcare Healthcare 87

Pharmaceutical Technology

AUGUST 8, 2022

But the pharmacology to quantify adherence also depends on race, gender, weight, and other factors. In addition to ensuring safety and data transparency, it is important that patient access is not affected, says Haga.

Food and Drug Administration 122

Food and Drug Administration FDA Medicine Patients 122

Quantified

JUNE 28, 2022

Equally, certification can support compliance, fair balance and consistent inclusion of important safety information. Mark holds degrees in Medicine and Pharmacology from the University of Manchester and studied business at Manchester Business School.

Sales 52

Sales Pharma Training Management 52

Pharmaceutical Technology

OCTOBER 10, 2022

Despite the recognized need and demand for options to treat female sexual dysfunction, several safety and access issues associated with the use of available options. All this development comes in the backdrop of a wider sense of stigma against the use of pharmacologic options for female sexual function, says Kingsberg.

Pharmacology 59

Pharmacology Side effects FDA Safety 59

Pharmaceutical Technology

FEBRUARY 17, 2023

In January, amidst calls to improve patient safety by optimizing licensed drug formulations, the FDA released a draft guidance that signalled a departure from the most commonly used method of identifying a new therapy’s ideal dosage. The clinical pharmacology knowledge also isn’t present at smaller companies, he adds.

FDA 115

FDA Side effects Pharmacology Patients 115

Pharmaceutical Technology

MARCH 16, 2023

However, health specialists refute most safety concerns for the use of drug classes as part of gender affirming care, citing years of research and care. As these drugs are not licensed for the specific indication of gender-affirming care, collecting safety data on off-label use is not viewed as a priority.

Ethics 144

Ethics Prescription Safety Healthcare 144