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Medical imaging modalities: A spotlight on the liver

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2022 Jan;161:108-118 [7] Marrero JA, Ahn J, Rajender Reddy K; Americal College of Gastroenterology. CA Cancer J Clin. 2021 May;71(3):209-249 [6] Rumgay H, Ferlay J, de Martel C, Georges D, Ibrahim AS, Zheng R, Wei W, Lemmens VEPP, Soerjomataram I. Global, regional and national burden of primary liver cancer by subtype. Eur J Cancer.

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The imperative of fridge-free vaccines

European Pharmaceutical Review

Li AB, Kluge JA, Guziewicz NA, et al. Long-term thermostabilization of live poxviral and adenoviral vaccine vectors at supraphysiological temperatures in carbohydrate glass. Sci Transl Med. 2010;2(19):ra12. Silk-based stabilization of biomacromolecules. J Control Release. 2015;10(219):416-430.

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Novel oral chemotherapeutic holds potential for stomach cancer patients

European Pharmaceutical Review

Perez EA, Hillman DW, Mailliard JA, et al. Direct translation of a protracted irinotecan schedule from a xenograft model to a phase I trial in children. J Clin Oncol, 1999; 17(6):1815-1824. Randomized Phase II Study of Two Irinotecan Schedules for Patients with Metastatic Breast Cancer Refractory to an Anthracycline, a Taxane, or both.

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NITROSAMINES: Where now?

European Pharmaceutical Review

López-Rodríguez R, McManus JA, Murphy NS, et al. Questions and Answers for marketing authorisation holders/applicants on the CHMP Opinion for the Article 5(3) of Regulation (EC) No 726/2004 referral on nitrosamine impurities in human medicinal products. EMA/409815/2020 Rev.13. Org Proc Res Dev. 2020; 24(9): 1558–1585. Cross KP, Ponting DJ.

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ESMO 2022: Ten key takeaways on Europe’s top oncology event

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14] Bex A, Uzzo R, Karam JA, et al. Adjuvant nivolumab plus ipilimumab (NIVO+IPI) vs placebo (PBO) for localized renal cell carcinoma (RCC) at high risk of relapse after nephrectomy: Results from the randomized, phase III CheckMate 914 trial. Annals of Oncology. 2022;33(suppl_7): S808-S869. DOI: 10.1016/annonc/annonc1089. [14]

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Anatomy of a ‘correlate of protection’ for T-cell vaccines

European Pharmaceutical Review

Zwart MP, Hemerik L, Cory JS, de Visser JA, Bianchi FJ, Van Oers MM, et al. Characterization of H5N1 influenza virus quasispecies with adaptive hemagglutinin mutations from single-virus infections of human airway cells. 2018;92(11):e02004-17. An experimental test of the independent action hypothesis in virus-insect pathosystems.