Tue.Dec 26, 2023

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AstraZeneca Goes With Gracell to Gain an Edge in Next-Generation Cell Therapies

MedCity News

AstraZeneca is paying $1 billion up front to acquire Gracell Biotechnologies, a clinical-stage cell therapy developer. The deal is the latest in a series of AstraZeneca moves intended to expand its presence in the burgeoning cell therapy field.

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BMS agrees to acquire Karuna Therapeutics for $14bn

Pharmaceutical Technology

Bristol Myers Squibb (BMS) has signed a definitive agreement for the acquisition of Karuna Therapeutics for $14bn in cash.

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Trending Sources

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Inside Planned Parenthood’s Partnership-Centric Approach to Expanding Abortion Access

MedCity News

Ambreen Molitor, Planned Parenthood’s national director of venture and innovation, discussed three partnerships her organization has launched this year to address barriers to abortion care. These partnerships tackle barriers such as cost, changing state laws and lack of emotional support.

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8 Tips to Build an Effective Manufacturing Sales Strategy

Spotio

Manufacturing sales is anything but simple. Fortunately, it’s far from impossible. You just need to implement an effective manufacturing sales strategy to meet your company’s revenue goals. We can help you with that! Once you equip your sales team with the strategy and technology they need to close deals, they’ll do so at a consistent clip.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Bristol Myers Squibb Makes Another M&A Move, Striking $4B Deal for RayzeBio

MedCity News

By acquiring RayzeBio, Bristol Myers Squibb gains a pipeline of radiopharmaceuticals and the infrastructure for manufacturing these targeted cancer therapies. In the second half of 2023 alone, BMS has committed about $24 billion to business development deals.

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How To Break Into Trauma Med Sales With Joseph Hutchison

Evolve Your Success

There is a myth that medical sales are very hard to get into, but if you put the time and effort into this program, you will get the job that you want. This is what Joseph “Joey” Hutchison learned from his successful journey in medical sales. After going through the Medical Sales Career Builder program, he was able to break into trauma med sales in just three months.

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More Trending

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Navigating the Complexities of Medical Sales Staff Recruitment: A Comprehensive Guide

Rep-Lite

Recruiting medical staff, including non-clinical roles such as device equipment specialists, department managers, or medical sales representatives, involves several complexities due to the unique nature of the healthcare industry. Medical sales staff recruitment firms may face challenges such as finding the right talent, ensuring compliance, incorporating innovation, and others.

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Report: The Top 4 Contributors To Food Insecurity

MedCity News

The contributors to food insecurity include age, having a disability, being on a fixed income and being a single parent, according to a recent report from FarmboxRx.

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Top 5 AI Stories of 2023

PharmExec

As this exciting technology exploded in 2023, Pharm Exec was there to cover it all.

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New Healthcare Climate Initiatives Lack Teeth, But They’re Paving the Way

MedCity News

Hospitals and hospital systems need to make clearer and more consistent demands for climate accountability from their suppliers, and they need to follow through with preferred green vendor programs and the like.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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ABBV-400 by AbbVie for Head And Neck Squamous Cell Carcinoma (HNSC): Likelihood of Approval

Pharmaceutical Technology

ABBV-400 is under clinical development by AbbVie and currently in Phase I for Head And Neck Squamous Cell Carcinoma (HNSC).

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Top 5 Most Popular Cold Chain Articles of 2023

Pharmaceutical Commerce

Items in this sector ranged touched on topics such as pharma shipping, container technology, and sustainability.

Pharma 52
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Exarafenib by Kinnate Biopharma for Non-Small Cell Lung Cancer: Likelihood of Approval

Pharmaceutical Technology

Exarafenib is under clinical development by Kinnate Biopharma and currently in Phase I for Non-Small Cell Lung Cancer.

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AZ makes another cell therapy play with $1.2bn Gracell buy

pharmaphorum

AstraZeneca agrees a $1.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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MRTX-1719 by Mirati Therapeutics for Biliary Tumor: Likelihood of Approval

Pharmaceutical Technology

MRTX-1719 is under clinical development by Mirati Therapeutics and currently in Phase II for Biliary Tumor.

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Top Social Media Trends of 2023

PharmExec

Five trends in pharmaceutical marketing from the past year.

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Difficult biotech investment ecosystem forces focus on value

Pharmaceutical Technology

In 2023, investors pursued pharmaceutical assets with value amidst an unstable economic environment.

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A Record Year for Disease Elimination

PharmaTech

WHO provides a look at the world’s health as the agency turns 75.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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NVG-111 by NovalGen for Mantle Cell Lymphoma: Likelihood of Approval

Pharmaceutical Technology

NVG-111 is under clinical development by NovalGen and currently in Phase I for Mantle Cell Lymphoma.

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Top 5 Pharmacy Times Clostridioides difficile Articles of 2023

Pharmacy Times

From newsworthy moments to groundbreaking research, these were the most-read Clostridioides difficile-related articles on Pharmacy Times in 2023.

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AWT-020 by Anwita Biosciences for Sarcomas: Likelihood of Approval

Pharmaceutical Technology

AWT-020 is under clinical development by Anwita Biosciences and currently in Phase II for Sarcomas.

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Top 5 Pharmacy Times Cardiovascular Articles of 2023

Pharmacy Times

From newsworthy moments to groundbreaking research, these were the most-read cardiovascular-related articles on Pharmacy Times in 2023.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Sacituzumab tirumotecan by Merck for Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer (HER2- Breast Cancer): Likelihood of Approval

Pharmaceutical Technology

Sacituzumab tirumotecan is under clinical development by Merck and currently in Phase II for Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer (HER2- Breast Cancer).

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Top 5 Pharmacy Times Heart Failure Articles of 2023

Pharmacy Times

From newsworthy moments to groundbreaking research, these were the most-read heart failure-related articles on Pharmacy Times in 2023.

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KSQ-4279 by F. Hoffmann-La Roche for Ovarian Cancer: Likelihood of Approval

Pharmaceutical Technology

KSQ-4279 is under clinical development by F. Hoffmann-La Roche and currently in Phase I for Ovarian Cancer.

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Streamlining bioprocessing for gene therapy

European Pharmaceutical Review

The number of approved gene therapies for the treatment of monogenetic disorders and diseases has increased in recent years, reflecting the field’s rapid advances and the development of revolutionary new technologies and techniques. The increasing adoption of technologies promoting safety, efficacy and reduced production costs has been a persistent trend that will continue to benefit the industry and help to treat a broader patient population.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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BI-765179 by Boehringer Ingelheim International for Head And Neck Squamous Cell Carcinoma (HNSC): Likelihood of Approval

Pharmaceutical Technology

BI-765179 is under clinical development by Boehringer Ingelheim International and currently in Phase I for Head And Neck Squamous Cell Carcinoma (HNSC).

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BI-765179 by Boehringer Ingelheim International for Cutaneous Squamous Cell Carcinoma (cSCC): Likelihood of Approval

Pharmaceutical Technology

BI-765179 is under clinical development by Boehringer Ingelheim International and currently in Phase I for Cutaneous Squamous Cell Carcinoma (cSCC).

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BR-790 by Jiangxi Qingfeng Pharmaceutical for Head And Neck Squamous Cell Carcinoma (HNSC): Likelihood of Approval

Pharmaceutical Technology

BR-790 is under clinical development by Jiangxi Qingfeng Pharmaceutical and currently in Phase I for Head And Neck Squamous Cell Carcinoma (HNSC).

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Sacituzumab tirumotecan by Merck for Metastatic Transitional (Urothelial) Tract Cancer: Likelihood of Approval

Pharmaceutical Technology

Sacituzumab tirumotecan is under clinical development by Merck and currently in Phase II for Metastatic Transitional (Urothelial) Tract Cancer.

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.