European Pharmaceutical Review

MARCH 1, 2023

The authors explained that these are commonly used for tagging proteins for study or attaching protein drugs to drug-delivering nanoparticles. To create the surface required, the team coated gold nanoparticles with bioconjugates maleimide (MAL) and N -hydroxysuccinimide ester (NHS).

Manufacturing 93

Manufacturing Engineering Leads Pharmaceutical 93

European Pharmaceutical Review

AUGUST 24, 2022

tag ® , inspired by the unique features of microtubule biology and perfectly suited for DAR 2 and DAR 4 ADCs. European Journal of Organic Chemistry. The post Actualising the power of antibody-drug conjugates as cancer therapeutics appeared first on European Pharmaceutical Review. New England Journal of Medicine. and Antibody?Drug?Conjugates.

Engineering 82

Engineering Side effects Marketing Patients 82

Healthcare Success

JULY 11, 2022

In 2018, Europe launched new privacy and security regulations to protect European citizens in Europe and on any website they browse—regardless of where the site is hosted. Google Analytics 4 captures data very differently than UA, so things like tagging, data fields, and interfaces will all need updating. Why is Google doing this?

Healthcare 95

Healthcare Healthcare Patients Marketing 95

Pharmaceutical Technology

MARCH 22, 2023

The pharmaceutical industry began using radio frequency identification (RFID) tags in the early 2000s. Pfizer was the first to use the tech, adding RFID tags to track a Viagra (sildenafil) shipment circa 2006. Twenty years ago, the cost of implementing RFID tags and the ecosystem (software) was much more expensive than today.

Food and Drug Administration 105

Food and Drug Administration Electronics Pharma FDA 105

pharmaphorum

NOVEMBER 16, 2022

Only a few years later, bluebird bio’s gene therapy, Zynteglo (betibeglogene autotemcel), was approved in the European market for the treatment of the rare blood disorder, beta thalassaemia. However, with a price tag of €1.58 How to navigate the new climate. At more than $2.1

Medicine 125

Medicine Marketing Healthcare Healthcare 125

Pharmaceutical Technology

JUNE 21, 2023

The high price tag may be hard to defend , but with lifetime treatment costs for haemophilia B reaching as high as $23m for some, the single-dose treatment could prove far more cost-effective. Despite the limited market, the price tags of haemophilia make it potentially lucrative. Haemophilia B is a rare condition.

Patients 98

Patients Food and Drug Administration Engineering Sales 98

pharmaphorum

AUGUST 26, 2022

The US biotech claimed conditional marketing approval from the European Commission for Roctavian (valoctocogene roxaparvovec) as a treatment for adults with severe haemophilia A, who don’t have a history of developing the antibodies that inhibit the activity of blood-clotting protein Factor VIII. million spread over five years.

FDA 109

FDA Marketing Competition Patients 109

European Pharmaceutical Review

MAY 11, 2023

1 This is assuming a $1M price tag for all gene therapies. Catherine Eckford is Editorial Assistant at European Pharmaceutical Review. Available from: [link] The post Realising milestones with gene therapy for SMA appeared first on European Pharmaceutical Review. What are the emerging modalities in the gene therapy sector?

Food and Drug Administration 70

Food and Drug Administration Government Healthcare Healthcare 70

European Pharmaceutical Review

JULY 11, 2022

These coronavirus RBDs are attached to a nanoparticle by protein tags, enabling the structure to display fragments from multiple viruses on a single nanoparticle. . The post CEPI provides $30m to advance novel coronavirus vaccine appeared first on European Pharmaceutical Review. The innovative protein ?“glue”

Manufacturing 93

Manufacturing Engineering Leads Medicine 93

European Pharmaceutical Review

NOVEMBER 10, 2022

BT-474 cell line was gene-edited to incorporate a green fluorescent protein (GFP) tag into late endosomes/lysosomes (green). The post Putting complex medicines under the microscope appeared first on European Pharmaceutical Review. Physical characterisation. Journal of Extracellular Vesicles, 10, e12130.

Medicine 96

Medicine Distribution Engineering Electronics 96

European Pharmaceutical Review

DECEMBER 27, 2023

This data has been captured by CAR T-cell registries that were established first by the Center for International Blood and Marrow Transplant Research (CIBMTR) and later by the European Society for Blood and Marrow Transplantation (EBMT). This is in addition to its considerable price tag. Annals of Oncology. 2022;33(3):259–75.

Manufacturing 83

Manufacturing Food and Drug Administration Patients Pharma 83