Sat.Nov 04, 2023

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QL-325 by QLSF Biotherapeutics for Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia): Likelihood of Approval

Pharmaceutical Technology

QL-325 is under clinical development by QLSF Biotherapeutics and currently in Phase I for Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia).

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Various Cancer Types, Drugs May Cause Thrombotic Microangiopathy, Impact Kidney Health

Pharmacy Times

Leung discusses that various cancer types and drugs can cause thrombotic microangiopathy and impact kidney health and the renal complications connected to hematologic malignancies.

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MBX-1416 by MBX Biosciences Inc for Hypoglycemia: Likelihood of Approval

Pharmaceutical Technology

MBX-1416 is under clinical development by MBX Biosciences Inc and currently in Phase II for Hypoglycemia.

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New Weight Loss Drugs May Have Cardiorenal Benefits for Patients with Kidney Disease

Pharmacy Times

Understanding the mechanisms leading to weight loss could help identify potential benefits for cardiorenal health in patients with chronic kidney disease.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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D3L-001 by D3 Bio for Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (HER2+ Breast Cancer): Likelihood of Approval

Pharmaceutical Technology

D3L-001 is under clinical development by D3 Bio and currently in Phase I for Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (HER2+ Breast Cancer).

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Navigating Medication Challenges in Kidney Disease, Updating Prior Drug Dosing Consensus

Pharmacy Times

Awdishu describes the implementation of new equations to accurately drug dose in patients as well as provide updated guidance on the dosing of older medications.

Medical 57

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Exercise May Reduce Mortality Among Patients on Dialysis, But Low Compliance Makes Concrete Recommendations Difficult

Pharmacy Times

Exercise has the potential to improve physical performance and fitness at the very least, but a multidisciplinary intervention may work better for patients with chronic kidney disease.

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Debio-4127 by Debiopharm International for Neuroendocrine Gastroenteropancreatic Tumors (GEP-NET): Likelihood of Approval

Pharmaceutical Technology

Debio-4127 is under clinical development by Debiopharm International and currently in Phase II for Neuroendocrine Gastroenteropancreatic Tumors (GEP-NET).

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Common Medications for Diabetic Kidney Disease May Be Linked to Increased Risk of Hyperkalemia

Pharmacy Times

Sodium-glucose cotransporter-2 inhibitors and sodium zirconium cyclosilicate may be paired with these kidney disease medications to reduce high serum potassium.

Medical 52
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Debio-4127 by Debiopharm International for Neuroendocrine Gastroenteropancreatic Tumors (GEP-NET): Likelihood of Approval

Pharmaceutical Technology

Debio-4127 is under clinical development by Debiopharm International and currently in Phase II for Neuroendocrine Gastroenteropancreatic Tumors (GEP-NET).

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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QL-325 by QLSF Biotherapeutics for Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia): Likelihood of Approval

Pharmaceutical Technology

QL-325 is under clinical development by QLSF Biotherapeutics and currently in Phase I for Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia).

52
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D3L-001 by D3 Bio for Gastroesophageal (GE) Junction Carcinomas: Likelihood of Approval

Pharmaceutical Technology

D3L-001 is under clinical development by D3 Bio and currently in Phase I for Gastroesophageal (GE) Junction Carcinomas.

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D3L-001 by D3 Bio for Gastroesophageal (GE) Junction Carcinomas: Likelihood of Approval

Pharmaceutical Technology

D3L-001 is under clinical development by D3 Bio and currently in Phase I for Gastroesophageal (GE) Junction Carcinomas.

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HUC-3443 by Huons for Idiopathic (Essential) Hypertension: Likelihood of Approval

Pharmaceutical Technology

HUC-3443 is under clinical development by Huons and currently in Phase II for Idiopathic (Essential) Hypertension.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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HUC-3443 by Huons for Idiopathic (Essential) Hypertension: Likelihood of Approval

Pharmaceutical Technology

HUC-3443 is under clinical development by Huons and currently in Phase II for Idiopathic (Essential) Hypertension.

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RPA-601 by Rocket Pharmaceuticals for Cardiomyopathy: Likelihood of Approval

Pharmaceutical Technology

RPA-601 is under clinical development by Rocket Pharmaceuticals and currently in Phase I for Cardiomyopathy.

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RPA-601 by Rocket Pharmaceuticals for Cardiomyopathy: Likelihood of Approval

Pharmaceutical Technology

RPA-601 is under clinical development by Rocket Pharmaceuticals and currently in Phase I for Cardiomyopathy.

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MBX-1416 by MBX Biosciences Inc for Hypoglycemia: Likelihood of Approval

Pharmaceutical Technology

MBX-1416 is under clinical development by MBX Biosciences Inc and currently in Phase II for Hypoglycemia.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Melpida by Elpida Therapeutics for Paraplegia: Likelihood of Approval

Pharmaceutical Technology

Melpida is under clinical development by Elpida Therapeutics and currently in Phase II for Paraplegia.

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PHIN-214 by PharmaIN for Portal Hypertension: Likelihood of Approval

Pharmaceutical Technology

PHIN-214 is under clinical development by PharmaIN and currently in Phase I for Portal Hypertension.

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PHIN-214 by PharmaIN for Portal Hypertension: Likelihood of Approval

Pharmaceutical Technology

PHIN-214 is under clinical development by PharmaIN and currently in Phase I for Portal Hypertension.

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HUC-3443 by Huons for Hypercholesterolemia: Likelihood of Approval

Pharmaceutical Technology

HUC-3443 is under clinical development by Huons and currently in Phase II for Hypercholesterolemia.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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HUC-3443 by Huons for Hypercholesterolemia: Likelihood of Approval

Pharmaceutical Technology

HUC-3443 is under clinical development by Huons and currently in Phase II for Hypercholesterolemia.

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