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Tackling the complex development landscape of pain medicines

European Pharmaceutical Review

The current medications (opioid and non-opioid) often force the patients to make an unfortunate choice between efficacy and debilitating side effects, leading to a cycling through multiple different therapies and suboptimal treatment response. The present unmet needs within chronic pain are not met with opioid therapies.

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How to Get into Pharmaceutical Sales

Rep-Lite

Getting into pharmaceutical sales and selling pharmaceutical products may require patience and persistence, but for individuals with the right qualifications and a passion for the field, it can be a rewarding and financially lucrative career. What is Pharmaceutical Sales? Why Pursue a Career in Pharmaceutical Sales?

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NICE to update endometriosis guidelines to improve diagnosis and surgical management

Pharmaceutical Technology

This delay in diagnosis ultimately leads to disease progression and associated complications, such as chronic pelvic pain and infertility, which greatly affects the patients’ quality of life. The post NICE to update endometriosis guidelines to improve diagnosis and surgical management appeared first on Pharmaceutical Technology.

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Paving the way for anti-Abeta active immunotherapy

European Pharmaceutical Review

Targeting toxic species of Abeta, such as multimers (with aducanumab and lecanemab) or pyroglutamate Abeta3-42 (with donanemab), induced significant removal of Abeta plaque load in the brains of Alzheimer’s patients, leading to the delay in cognitive decline. Treatment with the mAbs delayed cognitive decline by 2.6 months for lecanemab and 5.5

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FDA drug dosage optimisation guidelines signal clinical trial reform

Pharmaceutical Technology

However, Amgen and other pharmaceutical companies have been criticised when they opted to choose the drug’s dosage based on the MTD model, which is commonly used in dose-finding trials. The demand came amid concerns that the drug causes a slew of side effects such as nausea, diarrhea, and liver issues.

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