article thumbnail

After a slow start for expensive CAR-T therapies, drug developers revisit oral therapies for blood cancer

pharmaphorum

But along with strong efficacy come some considerable risks and costs: cytokine release syndrome (CRS), where a patient’s immune system becomes dangerously over-stimulated, and neurotoxicity are potential side effects that need to be managed. Side effects and cost implications.

article thumbnail

Ethnopharmacology: traditional medicine and modern drug discovery

Pharmaceutical Technology

While 80% of the world’s population practices some form of traditional medicine, according to the World Health Organization (WHO), the practice is regularly discredited due to a lack of scientific support and regulation as well as evidence of negative side effects with certain medicines.

Medicine 105
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Understanding the evidence used in drug product withdrawals

European Pharmaceutical Review

They enable a range of observational study designs to be used where researchers study a period of exposure to a particular medicine and compare it with a control period of non-exposure in the same patient to establish any changes in the risk of adverse side effects. EMA/95098/2010. Internet] European Medicines Agency.

Medicine 111
article thumbnail

Pharmaceutical Patents: A Challenge for Malaysia

Contrarian Sales Techniques

There was an article that examine the market for generic medicines in the Malaysia, following the introduction of the first generic patent in 2010 and the introduction of generic patent law in 2012. There are some countries in the world that do not require waiting for patent expiration to produce a generic version of a drug.

article thumbnail

Leading innovators in anti-inflammatory anaesthetics for the pharmaceutical industry

Pharmaceutical Technology

Innovation S-curve for the pharmaceutical industry Anti-inflammatory anaesthetics is a key innovation area in pharmaceuticals Local anaesthetics have potent anti-inflammatory properties, with fewer side effects compared with traditional anti-inflammatory agents of the NSAID and steroid groups.

article thumbnail

Leading innovators in ssRNA virus peptides for the pharmaceutical industry

Pharmaceutical Technology

Peptide-based therapies are versatile, highly efficacious, and have a tolerable side effect profile. Patent volumes related to ssRNA virus peptides Company Total patents (2010 - 2021) Premium intelligence on the world's largest companies Johnson & Johnson 419 Unlock company profile GSK 419 Unlock company profile C.