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First RNA CAR-T therapy autoimmunity trial shows potential

European Pharmaceutical Review

Study data from a major trial has demonstrated RNA CAR-T (rCAR-T) therapy Descartes-08 facilitated significant and long-lasting clinical improvement in generalised myasthenia gravis (gMG). This is the first clinical trial using rCAR-T to treat autoimmunity.

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Clinical Overview: Asceniv IVIG for Primary Humoral Immunodeficiency Disease

Pharmacy Times

Asceniv is a plasma-derived polyclonal IVIG drug product designed to prevent serious bacterial infections in patients with primary humoral immunodeficiency disease.

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argenx enrols new cohort in Phase II multifocal motor neuropathy study

Pharmaceutical Technology

It involves an IVIg dependency and monitoring period, with two cohorts being dosed over 16 weeks. ARDA (NCT05225675) is a randomised, double-blind, placebo-controlled, multicentre study evaluating the effects of two dose regimens of ARGX-117 in MMN-diagnosed adults. MMN is a rare, progressive muscle disorder primarily affecting men.

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