Watch These 4 Large Drug Stocks Amid the Booming Industry

Image showing an investor looking at his pharma stocks performance
The biotechnology and drug sectors performed well in the second half of 2022 after struggling in the first six months. This was largely due to the improving regulatory environment and the uptick in M&A activity. Moreover, the companies' pipeline successes and positive clinical data have helped lift the market's performance. Despite the uncertainty surrounding the global economy, the pharmaceutical industry has continued to deliver positive regulatory updates and clinical data.


Despite the uncertainty surrounding the global economy, the drug and biotechnology sectors have continued to perform well in the second half of 2022. This is due to the positive clinical data and the improving regulatory environment. In addition, the companies' pipeline successes and the potential for innovation are expected to continue driving the market in the next few years. Some of the prominent drugmakers that are worth keeping an eye on are Johnson & Johnson, Novo Nordisk, Merck and Astra Zeneca.



Industry Picture

The large-cap pharmaceutical companies that are part of the industry are known for developing multi-million dollar drugs for a wide range of therapeutic areas, such as neurology, oncology, and cardiovascular and metabolism. Some of these also make vaccines, medical devices, and animal health products.


These companies spend a lot of money on their pipeline and development programs. They are committed to continuous innovation, which is a key characteristic of the pharmaceutical industry. The continuous development of new medicines is also a major factor that drives the industry's performance.



What Influence the Future of the Large-Cap Pharma Industry?

The continuous development of new medicines is also a key factor that drives the industry's performance. Large-cap pharmaceutical companies are constantly investing in their R&D programs to improve their product pipeline. Successful product line extensions and the positive clinical study results of new medicines are some of the factors that can help boost the stock price of these companies.


The collaboration and acquisition activity of the pharmaceutical industry is also a major factor that drives the industry's performance. Due to the time it takes to develop new medicines, large pharmaceutical companies are constantly acquiring small and mid-sized biotechnology firms to build their pipeline.


The acquisition activity of large pharmaceutical companies is also a result of the lackluster sales of older drugs, the government's scrutiny of the pricing of drugs, and the emergence of new tech firms such as Google and Apple. These factors have prompted many companies to focus their M&A efforts on lucrative areas such as cancer and gene therapy.


In addition, the increasing number of collaborations and partnerships between large pharmaceutical companies and smaller firms has also prompted many companies to focus their acquisition efforts on lucrative areas. The most prominent deal of the year was the acquisition of Horizon Therapeutics by Genentech.


A number of factors affect the performance of the pharmaceutical industry, such as the failure of key pipeline candidates and the delays in the approval of certain new medicines. This can lead to significant losses for large companies. Other factors such as the generic competition for older drugs and the pricing pressure are also contributing to the industry's decline.


The various factors that affect the pharmaceutical industry's performance are also contributing to the uncertainty surrounding the global economy. The rising interest rates, the weakening dollar, and the war in Europe are making the situation even more unpredictable.


The pandemic has caused uncertainty about the future of the pharmaceutical industry. In 2021, the demand for physician-administered drugs decreased due to the outbreak. However, in the last quarter of that year, the infection rates spiked due to the emergence of the Omicron variant. In 2022, the different waves of concern started to dominate the market. There is still a lot of uncertainty about the impact of the pandemic on the industry's performance.



Bright Prospects Indicates by Zacks Industry Rank 

The large-cap pharmaceutical industry, which is a part of the Medical sector, has a favorable Industry rank of A. The industry's average rating is computed on the basis of all the stocks in the group.


The large-cap pharmaceutical industry carries a solid Industry rank of 83. This sector is currently in the top 33% of all the 250 industries on the basis of the number of companies in the group. According to our research, the top 50% of the industries that have a favorable Industry rank perform better than the bottom 50%.


Before we discuss the various factors that affect the pharmaceutical industry's performance, let's first take a look at its current valuation and compare it with the market.



Industry Versus S&P 500 & Sector

The pharmaceutical industry has performed well this year, as it has outperformed the broader market's S&P 500 and the medical sector. It has gained 12.0% so far this year, against the 17.6 decline of the S&P 500 and the 16.9% decline of the medical sector.



 Keep an Eye On These 4 Large Drugmakers


  • Merck

The multiple blockbusters of drugmaker, Merck, such as Keytruda, are expected to drive the company's sales in the next few years. The company's sales have been supported by the ongoing recovery in the global economy and strong demand for its vaccines against HPV-related cancers.


The company's Keytruda is expected to continue driving its top-line growth as it continues to expand into new markets and indications. In addition, its Animal Health business is expected to continue contributing to the company's sales in the next few years. The multiple cancer pipeline of the company, which includes Keytruda, should help drive its long-term growth.


The stock of this company has gained 44.7% so far this year. The current year's earnings estimate has risen from $7.31 to $7.38, while that for the next year has increased from $7.21 to $7.34. Currently, the company has a three-year long-term earnings estimate of $7.34 per share.


  • Johnson & Johnson

The diversified business model of Johnson & Johnson is its biggest strength. The company, which is a global healthcare company, operates through different divisions such as pharmaceuticals, medical devices, and consumer products. Its ability to withstand various economic cycles helps it maintain its profitability.


The company's pharmaceutical unit has been performing well, as it has been supported by the multiple blockbusters, such as Darzalex and Stelara, as well as the contributions from newer drugs, such as Erleada and Tremfya. J&J's outlook for the business remains positive, as it continues to expect its pharmaceutical business to grow at a high rate in 2023.


The company's MedTech division has been performing well, as it is focused on growing this business through the launch of new products. J&J is also making progress on its pipeline and line extensions. It has taken significant steps to resolve its opioid and talc litigation.


The current year's earnings estimate for Johnson & Johnson has been improving over the past 60 days. The firm's earnings per share are now expected to be $10.04 in 2022.


  • Novo Nordisk

One of the leading diabetes portfolios of Novo Nordisk is Ozempic, which is an once-weekly injection of semaglutide. The drug has been performing well since its launch. It is expected to continue driving the company's top-line growth in the coming years. Another product, Rybelsus, is also gaining popularity.


The US Food and Drug Administration (FDA) has approved Wegovy, which is a 2.4-mg injection for the treatment of obesity. Other products, such as Xultophy and Saxenda, are also gaining popularity. Label expansion for these drugs is expected to boost sales.


The current year's earnings estimate for Novo Nordisk has dropped from $3.07 to $3.06. The same for the next year has decreased from $4.01 to $3.76. Novo Nordisk, which is a #3 ranked stock, has gained 18.6% this year.


  • AstraZeneca

AstraZeneca's key products, such as Imfinzi and Lynparza, are expected to continue driving its revenues. Its pipeline is strong, and it has been engaging in strategic collaborations and external acquisitions to boost its pipeline. The company's cost-cutting efforts are also expected to drive earnings. Alexion's acquisition of AstraZeneca strengthens its immunotherapies franchise, adding several new products to the company's top line.


The current year's earnings estimate for Anglo-Swedish drugmaker AstraZeneca has been improving over the past 60 days. The firm's earnings per share are now expected to be $3.36 in 2022 and $3.66 in 2023.


**The opinions and views expressed here are those of the author, and do not necessarily reflect the views and opinions of the company or its subsidiary, or those of Nasdaq, Inc.**

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