Sat.Mar 04, 2023 - Fri.Mar 10, 2023

article thumbnail

Pfizer hopes to nose out competition with approval for new migraine nasal spray Zavzpret

Fierce Pharma

Pfizer hopes to nose out competition with approval for new migraine nasal spray Zavzpret kdunleavy Fri, 03/10/2023 - 10:22

article thumbnail

First nasal monoclonal antibody COVID-19 treatment shows potential

European Pharmaceutical Review

A pilot study has demonstrated that a nasal version of the drug Foralumab, an anti-CD3 monoclonal antibody suppressed the inflammatory T cell response and decreased lung inflammation in patients with COVID-19. “This is the first nasal monoclonal antibody—other monoclonal antibody treatments were delivered intravenously and are no longer given as treatment because they are not effective against currently circulating viral variants,” explained Dr Howard Weiner, founder and Director of the Brigham

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Cybersecurity in the Connected Medical Future

MedCity News

The healthcare industry of the future will be defined by interoperable systems that need to securely share critical data across devices, distributed applications, and networks.

Medical 122
article thumbnail

Smartphone Photos to Detect Anemia

Medgadget

Researchers at University College London and at the University of Ghana have developed a smartphone-based system that can detect anemia through simple photos taken using the phone’s camera. The technology is intended for use in low- and middle-income countries where access to routine medical diagnostics may be unreliable. The process involves obtaining images of areas of the body which are least pigmented, including the white of the eye, the lower eyelid, and the lip.

article thumbnail

Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

article thumbnail

'The Top Line': Why pharma needs to ramp up its use of AI and machine learning, plus this week's headlines

Fierce Pharma

'The Top Line': Why pharma needs to ramp up its use of AI and machine learning, plus this week's headlines tcarey Thu, 03/09/2023 - 15:25

Pharma 247
article thumbnail

New NHS cell and gene therapy centre opens

European Pharmaceutical Review

Today marks the opening the NHS Blood and Transplant (NHSBT)’s new Clinical Biotechnology Centre (CBC) in Bristol. The state-of-the-art facility was part-funded by a £9.43 million Government grant and is designed to expand the UK’s ability to manufacture new gene and cell therapies. The CBC will help the UK grow its cell and gene therapy industry in a rapidly growing international market.” “The CBC will help the UK grow its cell and gene therapy industry in a rapidly growing international

More Trending

article thumbnail

New facility boosts UK’s cell and gene therapy manufacturing capacity

Pharmaceutical Technology

On 10 March, the National Health Service Blood and Transplant (NHSBT) opened a new Clinical Biotechnology Centre (CBC) with the aim of improving the UK’s ability to develop and manufacture cell and gene therapies. A £9.3 million ($11 million) grant is being used to build the facility in Bristol where therapies for currently incurable diseases, such as some forms of cancer, sickle cell disease, and cystic fibrosis can be manufactured.

article thumbnail

FDA calls expert hearing for Intercept’s high-profile NASH application for Ocaliva

Fierce Pharma

FDA calls expert hearing for Intercept’s high-profile NASH application for Ocaliva aliu Fri, 03/10/2023 - 10:49

FDA 272
article thumbnail

An Inside Look at Pharma Revenue Management

PharmExec

According to the 2023 State of Revenue Report, pharma companies are prioritizing digital transformation while struggling with inflation and supply chain disruptions.

Pharma 105
article thumbnail

Consumerism, Customer Experience at Healthcare’s Forefront

MedCity News

Healthcare consumerism and prioritizing the customer experience to boost loyalty are key focus areas for providers and payers in the months and years ahead.

article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Eli Lilly places price cap of $35 on out-of-pocket insulin cost

Pharmaceutical Technology

Eli Lilly has announced that it will reduce the price of its most commonly used insulin, Humalog, in the US, by 70% and cap the out-of-pocket cost for those on commercial insurance at $35. This follows on from recent US federal action, the Inflation Reduction Act, that legislated reducing the Medicare beneficiary insulin out-of-pocket costs at $35 a month.

article thumbnail

Bucking FDA, independent panel backs Roche's lucrative lymphoma expansion bid for Polivy

Fierce Pharma

Bucking FDA, independent panel backs Roche's lucrative lymphoma expansion bid for Polivy aliu Thu, 03/09/2023 - 17:22

FDA 265
article thumbnail

Congress Probes PBM Link to Higher Drug Prices

PharmExec

Latest investigation signals more scrutiny of pharmacy benefit managers and their role in treatment cost and coverage.

article thumbnail

Elevance Health: Long Covid Patients Are at Increased Risk for Cardiovascular Problems, Mortality

MedCity News

A recent Elevance Health study found that long Covid patients are 2.35 times more likely to experience cardiac arrhythmia and 3.64 times more likely to experience pulmonary embolism. The study also discovered higher mortality rates among long Covid patients.

Patients 114
article thumbnail

How to Stay Competitive in the Evolving State of Martech

Marketing technology is essential for B2B marketers to stay competitive in a rapidly changing digital landscape — and with 53% of marketers experiencing legacy technology issues and limitations, they’re researching innovations to expand and refine their technology stacks. To help practitioners keep up with the rapidly evolving martech landscape, this special report will discuss: How practitioners are integrating technologies and systems to encourage information-sharing between departments and pr

article thumbnail

Incannex partners with Catalent to manufacture psilocybin

Pharmaceutical Technology

Incannex Healthcare has collaborated with New Jersey-based pharma company Catalent for the development and manufacturing of a cGMP-grade psilocybin drug product for clinical trials and potential commercial use. The drug product is designed for use in the psilocybin-assisted psychotherapy drug development programme of Incannex for generalised anxiety disorder.

article thumbnail

Sanofi's site modernization spree rolls on with plan to shift 2,000 staffers to new flexible workspace in New Jersey

Fierce Pharma

Sanofi's site modernization spree rolls on with plan to shift 2,000 staffers to new flexible workspace in New Jersey fkansteiner Tue, 03/07/2023 - 10:50

216
216
article thumbnail

Promoting health equity for women: Highlights from scientific literature

Clarivate

As the world celebrates International Women’s Day, the Institute for Scientific Information at Clarivate explores an area of disproportionate inequality for women: health equity. Today is International Women’s Day. Each year, the United Nations acknowledges International Women’s Day as a day to not only honor women, but also bring awareness to prevailing challenges faced by women and girls around the world [1].

article thumbnail

Gen Z-Focused Mental Health Platform Founded by Stanford Psychologist Raises $6M

MedCity News

Wave Life — a mental health platform designed for Gen Z — recently closed a $6 million seed investment led by Santé Ventures. The company — which was founded by Sarah Adler, a clinical psychologist and clinical associate professor at Stanford’s psychiatry department — will use the funding to move further into the employer market and conduct research on its care model’s outcomes.

Marketing 114
article thumbnail

What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

article thumbnail

CNM-Au8 could address vision problems in multiple sclerosis

Pharmaceutical Technology

Clene has presented updated trial results for its Visionary MS Phase II clinical trial for its lead pipeline candidate, CNM-Au8. The trial is investigating CNM-Au8 as a treatment for patients with relapsing forms of multiple sclerosis (MS) with chronic optic neuropathy. The agent has a first-in-class mechanism of action within the MS portfolio, as it is a first drinkable treatment based on a nanocrystalline gold suspension that has reached late-stage development for MS.

article thumbnail

Sarissa's overhaul of Amarin's board is complete with resignation of 7 holdover members

Fierce Pharma

Sarissa's overhaul of Amarin's board is complete with resignation of 7 holdover members kdunleavy Tue, 03/07/2023 - 09:41

246
246
article thumbnail

Targeting the new ‘Golden Girls’

PharmaVoice

With unprecedented buying power, women over 50 wield a lot of influence — but are still underserved by pharma. Urovant hopes to change that with its potential blockbuster drug.

Pharma 98
article thumbnail

The Healthcare Interoperability Policies Driving the Conversation at ViVE [Sponsored]

MedCity News

Sandy Vance, HLTH’s senior adviser, Interoperability, offered a preview of the interoperability pavilion at ViVE and what she hopes to achieve at the conference this year.

article thumbnail

Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

article thumbnail

US FDA approves Pfizer’s migraine nasal spray Zavzpret

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has granted approval for Pfizer ’s Zavzpret (zavegepant) for the acute treatment of migraine in adult patients with or without aura. Zavzpret is claimed to be the first and only calcitonin gene-related peptide (CGRP) receptor antagonist nasal spray approved to treat migraine. It is a third-generation, selective and structurally unique, small molecule CGRP receptor antagonist and is currently under clinical development with oral and intranasal formulation

article thumbnail

AbbVie CEO Gonzalez scored $26M in 2022 pay as cash cow Humira neared patent cliff

Fierce Pharma

AbbVie CEO Gonzalez scored $26M in 2022 pay as cash cow Humira neared patent cliff aliu Tue, 03/07/2023 - 10:54

246
246
article thumbnail

Ultrasound Catheter to Treat Hypertension

Medgadget

Researchers at Columbia University Irving Medical Center and the Université de Paris, France, have tested an ultrasound denervation catheter in its potential to treat hypertension. The technology is called the Paradise ultrasound denervation device and it has been developed by ReCor Medical , a medtech company with offices in California and the UK. The concept is based on the phenomenon whereby overactive neural activity in the kidney can lead to increases in sodium and water retention, underlyi

Medical 95
article thumbnail

Lawmakers Are Cracking Down on Companies Using Health Data for Advertising

MedCity News

Three senators recently introduced legislation that would ban the use of health data for advertising and marketing purposes. The proposed legislation comes amid media reports claiming that data brokers are selling social media companies patients’ location data, as well as reports that hospitals and digital health startups are collecting patients’ online data and sharing it with tech giants such as Facebook and Google.

Media 117
article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

US FDA approves Shorla’s oncology drug for T-cell leukaemia

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has granted approval for Shorla Oncology’s Nelarabine Injection, an oncology drug, to treat T-cell leukaemia, an aggressive blood and bone marrow cancer that progresses quickly. The oncology drug has been approved to treat T-cell Lymphoblastic Lymphoma (T-LBL) and T-cell Acute Lymphoblastic Leukemia (T-ALL).

article thumbnail

In SCOTUS filing, Amgen claps back at Sanofi and Regeneron in long-running patent feud

Fierce Pharma

In SCOTUS filing, Amgen claps back at Sanofi and Regeneron in long-running patent feud fkansteiner Thu, 03/09/2023 - 08:45

230
230
article thumbnail

Drug Solutions Podcast: How CROs Adapt Themselves in the Ever-Changing Landscape of Cell and Gene Therapies

PharmaTech

In this episode, Rhonda Henry and Adam Mendizabal from Emmes discuss the role CROs play in cell and gene therapies undergoing clinical trials at all stages.

98
article thumbnail

Zocdoc Partners With Zaya Care for Pregnancy, Postpartum Services

MedCity News

Through the partnership, patients can find and book appointments with Zaya’s providers via Zocdoc’s website or app. The partnership represents the first time Zocdoc will have lactation consultants available on its marketplace, said Dr. Oliver Kharraz, Zocdoc founder and CEO.

article thumbnail

ABM Evolution: How Top Marketers Are Using Account-Based Strategies

In times of economic uncertainty, account-based strategies are essential. According to several business analysts and practitioners, ABM is a necessity for creating more predictable revenue. Research shows that nearly three-quarters of marketers (74%) already have the resources needed to build successful ABM programs.