Sun.Sep 11, 2022

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Many preventive medical services cost patients nothing. Will a Texas court decision change that?

MedCity News

A key part of the ruling by Judge Reed O’Connor of the U.S. District Court for the Northern District of Texas says one way that preventive services are selected for the no-cost coverage is unconstitutional. Another portion of his ruling says a requirement that an HIV prevention drug therapy be covered without any cost to patients violates the religious freedom of an employer who is a plaintiff in the case.

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ESMO: TIL therapy improves on Yervoy in melanoma trial

pharmaphorum

A personalised cell therapy based on tumour-infiltrating lymphocyte (TIL) cells has been shown to be more effective at improving progression-free survival than Bristol-Myers Squibb’s immunotherapy Yervoy in patients with advanced melanoma. It is the first time that a cell therapy for solid tumours has been tested in a phase 3 trial, and the first time that the approach has been directly compared with standard second-line immunotherapy in melanoma.

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Report: More than 11M middle-income seniors won’t be able to afford long-term care by 2033

MedCity News

Middle-income seniors are those who are unlikely to qualify for Medicaid but do not have adequate resources to pay for the housing and care options they need. The lead author called for efforts to be taken to improve the affordability of long-term care for seniors, particularly for those of lower income.

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ESMO: SpringWorks notches up a win in desmoid tumours

pharmaphorum

Hard on the heels of a new $575 million partnership with GSK, US biotech SpringWorks Therapeutics has reported phase 3 data at ESMO that sets up regulatory filings for its lead drug nirogacestat in a rare and aggressive form of soft tissue cancer. The results of the DeFi trial of nirogacestat in 142 adults with progressing desmoid tumours showed a significant 71% improvement with the drug on progression-free survival (PFS) compared to placebo, with an overall response rate of 41% and 8%, respect

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Reducing burnout among mental health workers: How community behavioral health clinics support their clinician teams

MedCity News

Here are some of the principles we have seen that effective organizations embrace to reduce burnout that could serve as a guide for the larger mental health clinic community.

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BMS scores first approval for psoriasis therapy Sotyktu

pharmaphorum

Bristol-Myers Squibb’s deucravacitinib– one of the main pipeline assets in its $74 billion takeover of Celgene in 2019 – has been approved in its first market as a treatment for moderate-to-severe plaque psoriasis. The US FDA has cleared the first-in-class tyrosine kinase 2 (Tyk2) inhibitor as Sotyktu , and BMS says it now plans to launch the new drug later this month, aiming to mount a challenge to Amgen’s $2.3 billion oral psoriasis therapy Otezla (apremilast).

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Sell More Through Internal and External Motivation

Contrarian Sales Techniques

At first glance, it may seem better for a salesperson to be intrinsically motivated than extrinsically motivated, but in fact, it is not. Intrinsic motivation is in every possible way in opposition to external motivation, because it refers to an inner desire that drives a person's behaviour. 1. What is Internal and External Motivation? 1.1 Internal motivation occurs when an impulse is exerted in response to a specific stimulation such as the desire for a new sales deal, a new prospect, or an opp

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How to Sell More with Confidence

Contrarian Sales Techniques

Self-confidence is a belief in how well you can do something, but it is not a measure of your actual abilities. Self-confidence can mean different things to different people, but for me, it means believing in myself. For instance, you can have zero confidence in your cooking ability, and still you believe that you’ll do just fine if you get started.

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