Thu.Aug 04, 2022

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Tapping into pharma’s growing opportunities in digital health

Pharmaceutical Technology

Soaring patient numbers are stretching hospital capacity across the globe, forcing healthcare providers and their partners to think laterally about how to meet the demand without doubling their resources. Smarter diagnostic tools and more sophisticated remote- and self-care models will have an increasingly important role to play, as long as any advances are seen to deliver excellent outcomes and a better patient experience.

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3 reasons you should use NLP to make sense of SDOH

MedCity News

Obtaining an understanding of how specific SDOH factors affect individuals is extremely difficult because SDOH data is not methodically collected by clinicians.

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North America is seeing a hiring boom in pharmaceutical industry machine learning roles

Pharmaceutical Technology

North America extended its dominance for machine learning hiring among pharmaceutical industry companies in the three months ending May. The number of roles in North America made up 63.9% of total machine learning jobs - up from 62.6% in the same quarter last year. That was followed by Europe, which saw a 0.6 year-on-year percentage point change in machine learning roles.

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FlipMD launches physician hiring platform to eliminate recruiting’s ‘spray and pray’ approach

MedCity News

FlipMD recently launched a recruiting platform designed to help healthcare providers, drugmakers and digital health companies find qualified physicians to fill a variety of roles — whether they’re clinical, nonclinical, full time or part time. Physicians on flipMD’s platform can also get paid to refer qualified candidates for positions.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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3 Ways to Build More Trust With Customers

Salesforce

For many companies, being seen as trustworthy by customers is an ultimate goal. But what does it really mean to have trust and build trust with customers? In a recent conversation on the Blazing Trails podcast , marketing guru Seth Godin and Salesforce vice president and global innovation evangelist Brian Solis discussed the issues around trust and how companies can get to know their customers better.

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Disappointing data lead Pfizer to drop heart drug acquired as part of $11B deal

MedCity News

Pfizer is stopping work on a drug for a rare heart disease after an interim look at Phase 3 data indicated that the study was unlikely to succeed. The small molecule came to Pfizer’s drug pipeline as part of the $11.4 billion acquisition of Array Biopharma in 2019.

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Most Medicare beneficiaries concerned about healthcare cost inflation, survey finds

MedCity News

About 95% of Medicare beneficiaries are anxious about inflation’s impact on healthcare costs, with 45% saying costs have already increased because of inflation, the eHealth survey discovered.

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Keytruda fluffs its lines in prostate, liver cancer trials

pharmaphorum

Two phase 3 trials of Merck & Co’s Keytruda in metastatic castration-resistant prostate cancer (CRPC) and advanced liver cancer have ended in failure, proving once again that cancer immunotherapy studies can be a hit-and-miss affair. The CRPC trial – KEYNOTE-921 – looked at the combination of Keytruda (pembrolizumab) with docetaxel in more than 1,000 patients who had not been treated with chemotherapy before, but who had seen disease progression despite earlier treatment with an anti-h

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NYC Health + Hospitals adds mental health services to virtual urgent care platform with $3.9 grant

MedCity News

NYC Health + Hospitals recently received a $3.9 million grant from Helmsley Charitable Trust to incorporate mental health services into ExpressCare, the health system’s virtual urgent care platform. The health system will also launch a version of its new tele-behavioral health services that is tailored to the New York City’s homeless residents.

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How can the pharma industry address the gap in talent recruitment and development?

pharmaphorum

Across the economy, several industries have seen a significant increase in staff turnover due to several factors including the COVID-19 pandemic, burnout, and increasing demand for workplace flexibility. This has resulted in staff and talent shortages, meaning that industries have been forced to respond quickly to stay afloat. In particular, for the pharmaceutical industry, these talent shortages bring about a host of difficult challenges.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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CareFirst, Headway partner to improve access to mental healthcare

MedCity News

Through the collaboration, CareFirst’s individual behavioral health practitioners can join Headway’s platform so members can filter, choose a provider, book and pay in one spot.

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Amgen splashes out on ChemoCentryx and its blockbuster hopeful

pharmaphorum

Ten months after ChemoCentryx scored an unexpected FDA approval for autoimmune disease therapy Tavneos, Amgen has swooped in with a $3.7 billion bid to buy out the company. The $52-per-share offer would give Amgen a drug that some analysts have described as a pipeline in a pill with $1 billion-plus sales potential, and is a sizeable premium on ChemoCentryx’ pre-deal announcement share price of just over $24.

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Amgen’s $3.7B ChemoCentryx acquisition adds a new piece to autoimmune strategy

MedCity News

Amgen’s drug portfolio boasts several biologic drugs that are blockbuster sellers. In acquiring ChemoCentryx for $3.7 billion, the pharmaceutical giant gains a company entirely focused on developing small molecule alternatives to biologic medicines.

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The 2022 Field Sales Benchmark Report is Now Available

Map My Customers

The 2022 Field Sales Benchmark Report is now available! This second annual survey by Map My Customers reveals the state of the field sales profession, trends in sales roles, sales time management, key sales statistics, and how technology impacts the way teams operate. Unlocking the ability to streamline your processes, maximize productivity, and close more deals starts first with understanding how sales professionals operate in their roles.

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Roles and Responsibilities of Specialized Clinical Supply Experts

When selecting a clinical supply provider, consideration often focuses upon the manufacturing, packaging, storage and distribution capabilities available that will, at face-value, be sufficient to meet the needs of the sponsor and their trial. However, there are human-based and knowledge-driven factors that are often overlooked that go beyond these basic physical capabilities and are integral to the development and delivery of high performing clinical supply chains.

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Exploring strategies and innovations that deliver balance and wellbeing, expand access to health care, and dramatically improve health outcomes

MedCity News

Recognizing the symbiotic relationship between chronic diseases and mental wellbeing highlights a need for common sense solutions that embrace a holistic, more balanced-oriented approach that has proven successful in nature for hundreds of thousands of years.

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Embracing the Renaissance of Small Molecule Drug Discovery

PharmExec

Pharma companies may benefit from meeting challenges and embracing small molecule drug discovery.

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Sinovac’s Covid-19 vaccine gets approval for use in children in Hong Kong

Pharmaceutical Technology

Sinovac Biotech has reported that its Covid-19 vaccine, CoronaVac, obtained approval from the Health Bureau of the Government of the Hong Kong Special Administrative Region of the People's Republic of China for usage in children of the age six months to three years. The consensus interim recommendations on Covid-19 vaccine use in children aged six months or above in Hong Kong were released by the Scientific Committee on Vaccine Preventable Diseases and the Scientific Committee on Emerging and Zo

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Top Priority for Califf is Combating Health Misinformation

PharmExec

Better clinical data needed, as well as strategies for tackling opioid abuse, tobacco use, and food safety.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Open Orphan to commence influenza human challenge study

PharmaTimes

Candidate exhibits a novel mechanism of action and differs considerably from previously approved drugs

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Pfizer takes pipeline blow as it abandons cardiomyopathy drug

pharmaphorum

Pfizer has stopped development of a drug to treat cardiomyopathy caused by a rare form of heart disease, after it proved ineffective in a phase 3 trial. PF-07265803 – a p38 mitogen-activated protein kinase (MAPK) antagonist also known as emprumapimod – was being tested as a treatment for symptomatic dilated cardiomyopathy (DCM) due to a mutation in the LMNA gene in the REALM-DCM trial.

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Poseida and Roche to develop cell therapies for hematologic cancers

Pharmaceutical Technology

Poseida Therapeutics and Roche have signed a strategic partnership and licence agreement to develop allogeneic CAR-T cell therapies for hematologic malignancies. The research and development (R&D) of various present and new ‘off-the-shelf’ cell therapies against targets in B-cell lymphomas, multiple myeloma and other hematologic indications are included in this alliance.

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Micro-targeted Provider Incentives to Reduce Total Cost of Care

Clarify Health

Principles of behavioral economics, including inertia, loss aversion, choice overload, and relative social ranking, have been applied to motivate personal health decisions, retirement planning, and savings behavior. However, they have been largely ignored in healthcare, specifically in regard to the design of physician incentive programs. Can behavioral economics be applied in healthcare?

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Accelerating Clinical Supply Through Integrated Drug Development

As the development pipeline for new drugs continues to grow, biopharmaceutical companies are re-evaluating how to best manage and balance resources across an increasing number of development projects and complex clinical trials. There are two approaches that can be used to speed a drug from development to clinic faster: timeline compression and parallel processing, but only one that considers the benefits of integrating clinical supply into the overall drug development process.

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COVID-19 health concern increases in July: Poll

Pharmaceutical Technology

The health concern over COVID-19 in July 2022 increased averaging at 27.7%, compared to 23.9% recorded in June 2022 , shows the COVID-19 concern index, which is measured by responses to an ongoing poll Verdict launched in March 2020. The poll has been tracking how the concerns over coronavirus have been changing over time. The poll asked how concerned the respondents were about the spread of coronavirus and included five options to choose from - very concerned, slightly concerned, neither concer

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Micro-targeted Provider Incentives to Reduce Total Cost of Care

Clarify Health

Principles of behavioral economics, including inertia, loss aversion, choice overload, and relative social ranking, have been applied to motivate personal health decisions, retirement planning, and savings behavior. However, they have been largely ignored in healthcare, specifically in regard to the design of physician incentive programs. Can behavioral economics be applied in healthcare?

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B2B Sales Strategy: 9 Key Steps For Success

Spotio

B2B sales is different than it was a few years ago. There are more decision-makers for sales reps to meet and touchpoints for them to navigate through than ever before. These things lead to longer sales cycles. The average B2B buyer in 2022 is so much more educated than they would have been in the early 2000s, which further complicating matters. Here are a few stats to prove the complexity of modern B2B sales: There are now an average of 6.8 people involved in every B2B purchase. 74% of B2B bu

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Business optimism declines in July 2022: Poll

Pharmaceutical Technology

Business optimism declined in July 2022 compared to June 2022, amid concerns over inflation as the cost-of-living pressures on households continued to grow in countries such as the UK, revealed the analysis of an ongoing poll by Verdict. Verdict has been conducting the poll to study the trends in business optimism during COVID-19 as reflected by the views of companies on their future growth prospects amid the pandemic.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Industry Perspective on API Quality–A Conversation with Niamh Lynch of Lonza

PharmaTech

Pharmaceutical Technology spoke with Niamh Lynch, Executive Director, Global Head of Quality, Lonza Small Molecules, Basel about best practices for API quality and the impact of the nitrosamine contamination situation.

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Moderna reports total revenues of $4.7bn in Q2 2022

Pharmaceutical Technology

Moderna has reported total revenues of $4.7bn in the second quarter (Q2) of the fiscal year 2022 as against $4.4bn in the year-ago quarter. For the first half (H1) of the year, total revenue stood at $10.8bn, a growth from $6.3bn in the same period in 2021. The revenue growth was attributed to the rise in sales of the company's Covid-19 vaccine. For the three months ended on 30 June 2022, the basic earnings per share (EPS) stood at $5.55, a decline from $6.93 in Q2 last year.

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Star OUTiCO involvement in COVID Infection Survey concludes

Star OUTiCO

The end of July coincided with the conclusion of the Star OUTiCO contribution to the COVID-19 Infection Survey project, and what an incredible contribution we have made. Some of the stats that showcase our efforts are superb, but they only tell some of the story of a project that has grown to a size no one could have imagined when we started during lockdown April 2020.

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Validcare announces the integration of Real-World Research (RWR) Ltd into the Validcare Digital 1st CRO platform

Pharma Leaders

Denver, CO. – August 2, 2022. Today, Validcare announces the integration of Real-World Research (RWR) Ltd into the Validcare Digital 1 st CRO platform. RWR is a global leader in providing Real-World Evidence solutions to the pharmaceutical, biotech and medical device industries. Dr. Stuart McCully, CEO of RWR said “Until now we’ve provided sponsors with the regulatory intelligence needed to run real-world evidence (RWE) studies.

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The New Clinical Trial Supply Chain: Resilient, Flexible, and Patient-Centric

The global landscape of clinical trials is rapidly changing as studies become more complex. An increasing number of sponsors are seeking enhanced flexibility in their supply chains to address a variety of clinical supply challenges, including patient demand and reducing delays. Demand-led supply and direct-to-patient distribution are next-generation solutions that are helping to meet these growing needs, allowing for more streamlined processes and patient-centric studies.